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Details
Link-It Detail - Disease - Lymphoma, Large-Cell, Anaplastic
Debug Stats
  • ### Total Build Time: 255 ms 87.019 KB
  • CONCEPT_NAME gt=8 ms Completed: 8 ms rowSize= 428 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 448 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=8 ms Completed: 8 ms rowSize= 991 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=9 ms Completed: 9 ms rowSize= 7.896 KB
  • CONCEPT_RELATIONSHIPS gt=153 ms Completed: 153 ms rowSize= 15.357 KB
  • CONCEPT_GENES gt=69 ms Completed: 69 ms rowSize= 60.559 KB
  • CONCEPT_XREFS gt=6 ms Completed: 6 ms rowSize= 1.166 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
Lymphoma, Large-Cell, Anaplastic C0206180
Ki-1+ Anaplastic Large Cell Lymphoma
Definition (1)
A systemic, large-cell, non-Hodgkin, malignant lymphoma characterized by cells with pleomorphic appearance and expressing the CD30 ANTIGEN. These so-called "hallmark" cells have lobulated and indented nuclei. This lymphoma is often mistaken for metastatic carcinoma and MALIGNANT HISTIOCYTOSIS.
Semantic Types (1)
Neoplastic Process (T191)
Parents (2)
img Lymphoma, T-Cell C0079772
img Lymphoma, Non-Hodgkin C0024305
Ancestral Roots
RootRoot Plus OneDepthParent
img Neoplasms C0027651img Neoplasms by Histologic Type C00276526img Lymphoma, T-Cell C0079772
img Immune System Diseases C0021053img Immunoproliferative Disorders C00210707img Lymphoma, T-Cell C0079772
img Hemic and Lymphatic Diseases C0018981img Lymphatic Diseases C00242287img Lymphoma, T-Cell C0079772
img Neoplasms C0027651img Neoplasms by Histologic Type C00276525img Lymphoma, Non-Hodgkin C0024305
img Immune System Diseases C0021053img Immunoproliferative Disorders C00210706img Lymphoma, Non-Hodgkin C0024305
img Hemic and Lymphatic Diseases C0018981img Lymphatic Diseases C00242286img Lymphoma, Non-Hodgkin C0024305
Relationships (80)

Relation Types:
diso_​to_​anat : 22
diso_​to_​chem : 11
diso_​to_​diso : 43
diso_​to_​phen : 2
diso_​to_​phys : 2


Relationships:
none : 30
eo_​disease_​maps_​to_​human_​disease : 1
is_​abnormal_​cell_​of_​disease : 7
is_​finding_​of_​disease : 2
is_​normal_​cell_​origin_​of_​disease : 5
is_​normal_​tissue_​origin_​of_​disease : 2
is_​not_​abnormal_​cell_​of_​disease : 2
is_​not_​normal_​cell_​origin_​of_​disease : 4
is_​primary_​anatomic_​site_​of_​disease : 2
isa : 21
may_​be_​molecular_​abnormality_​of_​disease : 2
parent_​is_​cdrh : 1
permuted_​term_​of : 1
Page Size
Current 25
  Page 1 of 4
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_PHEN95img genetic aspects C0017399
DISO_to_DISO71img Cutaneous tumor C0037286
DISO_to_CHEM64img Protein Tyrosine Kinase C0033681
DISO_to_DISO39img Complication Aspects C1171258
DISO_to_CHEM34img Antigens, CD30 C0054950
DISO_to_DISO33img Cutaneous tumor C0037286
DISO_to_CHEM31img Receptor Protein-Tyrosine Kinases C0206364
DISO_to_DISO31img Breast Neoplasms C1458155
DISO_to_PHEN27img genetic aspects C0017399
DISO_to_CHEM25img Protein Tyrosine Kinase C0033681
DISO_to_DISO25img Hodgkin Disease C0019829
DISO_to_CHEM18img Antigens, CD30 C0054950
DISO_to_CHEM15img Antineoplastic Agents C0003392
DISO_to_DISO14img Lymphomatoid Papulosis C0206182
DISO_to_DISO13img Complication Aspects C1171258
DISO_to_PHYS13img GENE EXPRESSION REG NEOPL C0017268
DISO_to_CHEM12img BIOCHEM TUMOR MARKERS C0041366
DISO_to_CHEM11img Immunoconjugates C0243020
DISO_to_CHEM10img Chimeric Oncogene Proteins C0029014
DISO_to_DISO10img HLH C0024291
DISO_to_DISO10img Hodgkin Disease C0019829
DISO_to_DISO9img Lymphoma, T-Cell C0079772
DISO_to_CHEM8img ACTIVIN RECEPT LIKE KINASES TYPE II C0676594
DISO_to_CHEM8img Activin Receptors, Type II C0676594
DISO_to_DISO8img Diffuse Large B-Cell Lymphoma C0079744
Genes (86)

Species:
human : 86
Page Size
Current 25
  Page 1 of 4
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanRNF21357674ring finger protein 213
img GENERIF, Score=1000, Pubmed Id: 12112524, UMLKSK CUI: C0206180
HumanLEF151176lymphoid enhancer-binding factor 1
img NCI, Score=801, Pubmed Id: 12707037, UMLKSK CUI: C0206180
HumanPTPN2226191protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
img NCI, Score=801, Pubmed Id: 7611181, UMLKSK CUI: C0206180
HumanSWAP7023075SWAP switching B-cell complex 70kDa subunit
img NCI, Score=801, Pubmed Id: 15163014, UMLKSK CUI: C0206180
HumanCOPS510987COP9 signalosome subunit 5
img NCI, Score=801, Pubmed Id: 12631617, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 12631617, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 12631617, UMLKSK CUI: C0206180
HumanMALT110892mucosa associated lymphoid tissue lymphoma translocation gene 1
img NCI, Score=801, Pubmed Id: 14997743, UMLKSK CUI: C0206180
HumanTFG10342TRK-fused gene
img NCI, Score=801, Pubmed Id: 10556217, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 10556217, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 10556217, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 11280613, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 12800156, UMLKSK CUI: C0206180
HumanSOCS39021suppressor of cytokine signaling 3
img NCI, Score=801, Pubmed Id: 15385932, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 15385932, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 15385932, UMLKSK CUI: C0206180
img GENERIF, Score=1000, Pubmed Id: 15385932, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 15385932, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 15385932, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 15385932, UMLKSK CUI: C0206180
HumanNR0B28431nuclear receptor subfamily 0, group B, member 2
img GENERIF, Score=937, Pubmed Id: 16825495, UMLKSK CUI: C0206180
HumanTCL1A8115T-cell leukemia/lymphoma 1A
img NCI, Score=801, Pubmed Id: 10786666, UMLKSK CUI: C0206180
HumanCXCR47852chemokine (C-X-C motif) receptor 4
img NCI, Score=801, Pubmed Id: 12645345, UMLKSK CUI: C0206180
HumanTNFRSF47293tumor necrosis factor receptor superfamily, member 4
img NCI, Score=801, Pubmed Id: 12958063, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 11426518, UMLKSK CUI: C0206180
HumanTRAF27186TNF receptor-associated factor 2
img NCI, Score=801, Pubmed Id: 11110706, UMLKSK CUI: C0206180
HumanTRAF17185TNF receptor-associated factor 1
img NCI, Score=801, Pubmed Id: 12782762, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 15644776, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 15644776, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 12754742, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 12782762, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 15644776, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 15644776, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 12754742, UMLKSK CUI: C0206180
HumanTPM47171tropomyosin 4
img NCI, Score=801, Pubmed Id: 12800156, UMLKSK CUI: C0206180
HumanTIMP17076TIMP metallopeptidase inhibitor 1
img NCI, Score=801, Pubmed Id: 15161657, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 12174874, UMLKSK CUI: C0206180
img GENERIF, Score=906, Pubmed Id: 15161657, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 12174874, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 12174874, UMLKSK CUI: C0206180
HumanTIA17072TIA1 cytotoxic granule-associated RNA binding protein
img GENERIF, Score=1000, Pubmed Id: 17493234, UMLKSK CUI: C0206180
HumanTCF76932transcription factor 7 (T-cell specific, HMG-box)
img NCI, Score=801, Pubmed Id: 12707037, UMLKSK CUI: C0206180
HumanSTAT5A6776signal transducer and activator of transcription 5A
img GENERIF, Score=901, Pubmed Id: 17922009, UMLKSK CUI: C0206180
HumanSTAT36774signal transducer and activator of transcription 3 (acute-phase response factor)
img NCI, Score=801, Pubmed Id: 14506160, UMLKSK CUI: C0206180
img GENERIF, Score=1000, Pubmed Id: 15895073, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 15161657, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 14506160, UMLKSK CUI: C0206180
HumanSPN6693sialophorin
img NCI, Score=801, Pubmed Id: 10091777, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 10786813, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 9160083, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 15104308, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 16019518, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 9160307, UMLKSK CUI: C0206180
HumanS100A96280S100 calcium binding protein A9
img NCI, Score=801, Pubmed Id: 8305759, UMLKSK CUI: C0206180
HumanCLIP16249CAP-GLY domain containing linker protein 1
img NCI, Score=801, Pubmed Id: 8161933, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 8161933, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 8161933, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 8222754, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 1450414, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 1450414, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 1450414, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 1450414, UMLKSK CUI: C0206180
HumanREL5966v-rel avian reticuloendotheliosis viral oncogene homolog
img NCI, Score=801, Pubmed Id: 15644776, UMLKSK CUI: C0206180
img NCI, Score=801, Pubmed Id: 15644776, UMLKSK CUI: C0206180
HumanRB15925retinoblastoma 1
img GENERIF, Score=734, Pubmed Id: 15161658, UMLKSK CUI: C0206180
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0206180Lymphoma, Large-Cell, Anaplastic0self