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Details
Link-It Detail - Disease - Lung Diseases, Interstitial
Debug Stats
  • ### Total Build Time: 348 ms 41.507 KB
  • CONCEPT_NAME gt=8 ms Completed: 8 ms rowSize= 352 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 1.219 KB
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=63 ms Completed: 63 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 549 bytes
  • CONCEPT_CHILDREN gt=23 ms Completed: 23 ms rowSize= 3.595 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.500 KB
  • CONCEPT_RELATIONSHIPS gt=199 ms Completed: 199 ms rowSize= 13.640 KB
  • CONCEPT_GENES gt=46 ms Completed: 46 ms rowSize= 19.302 KB
  • CONCEPT_XREFS gt=8 ms Completed: 8 ms rowSize= 1.161 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Lung Diseases, Interstitial C0206062
Definition (1)

Interstitial lung disease is the name for a large group of diseases that inflame or scar the lungs. The inflammation and scarring make it hard to get enough oxygen. The scarring is called pulmonary fibrosis.

Breathing in dust or other particles in the air are responsible for some types of interstitial lung diseases. Specific types include

  • Black lung disease among coal miners, from inhaling coal dust
  • Farmer's lung, from inhaling farm dust
  • Asbestosis, from inhaling asbestos fibers
  • Siderosis, from inhaling iron from mines or welding fumes
  • Silicosis, from inhaling silica dust

Other causes include autoimmune diseases or occupational exposures to molds, gases, or fumes. Some types of interstitial lung disease have no known cause.

Treatment depends on the type of exposure and the stage of the disease. It may involve medicines, oxygen therapy, or a lung transplant in severe cases.

Semantic Types (1)
Disease or Syndrome (T047)
Parents (1)
img Lung Diseases C0024115
Children (8)
img Sarcoidosis, Pulmonary C0036205
img Wegener Granulomatosis C0043092
img Radiation Pneumonitis C0206063
img Alveolitis, Extrinsic Allergic C0002390
img Pneumoconiosis C0032273
img Anti-Glomerular Basement Membrane Disease C0403529
img Histiocytosis, Langerhans-Cell C0019621
img Idiopathic Interstitial Pneumonias C2350236
Ancestral Roots
RootRoot Plus OneDepthParent
img Respiratory Tract Diseases C0035242img Lung Diseases C00241153img Lung Diseases C0024115
Relationships (114)

Relation Types:
diso_​to_​anat : 9
diso_​to_​chem : 27
diso_​to_​diso : 73
diso_​to_​phen : 2
diso_​to_​phys : 3


Relationships:
none : 83
associated_​with : 2
isa : 24
location_​of : 1
permuted_​term_​of : 1
related_​to : 3
Page Size
Current 25
  Page 1 of 5
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO282img Complication Aspects C1171258
DISO_to_DISO252img chemically induced C0007994
DISO_to_DISO180img Complication Aspects C1171258
DISO_to_DISO163img chemically induced C0007994
DISO_to_ANAT137img Lung C0024109
DISO_to_ANAT128img Lung C0024109
DISO_to_DISO121img Scleroderma, Systemic C0036421
DISO_to_DISO85img Lung Neoplasms C0024121
DISO_to_DISO81img Pulmonary Fibrosis C0034069
DISO_to_DISO76img Dermatomyositis C0011633
DISO_to_CHEM72img Immunosuppressive Agents C0021081
DISO_to_DISO72img Pulmonary Fibrosis C0034069
DISO_to_DISO69img Rheumatoid Arthritis C0003873
DISO_to_DISO65img Lung Neoplasms C0024121
DISO_to_DISO61img Pulmonary Hypertension C0020542
DISO_to_PHEN61img genetic aspects C0017399
DISO_to_ANAT57img In Blood C0005768
DISO_to_DISO56img Dermatomyositis C0011633
DISO_to_CHEM53img Antineoplastic Agents C0003392
DISO_to_CHEM52img Immunosuppressive Agents C0021081
DISO_to_ANAT46img Bronchoalveolar Lavage Fluid C0006279
DISO_to_ANAT45img In Blood C0005768
DISO_to_PHEN45img genetic aspects C0017399
DISO_to_CHEM39img Antineoplastic Agents C0003392
DISO_to_DISO38img Arthritis, Rheumatoid C0003873
Genes (122)

Species:
human : 122
Page Size
Current 25
  Page 1 of 5
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanSFTPA1653509surfactant protein A1
INFERRED, Score=800, UMLKSK CUI: C0206062
HumanHPS489781Hermansky-Pudlak syndrome 4
INFERRED, Score=800, UMLKSK CUI: C0206062
HumanNOD264127nucleotide-binding oligomerization domain containing 2
img GENERIF, Score=1000, Pubmed Id: 17393391, UMLKSK CUI: C0206062
img OMIM, Score=1000, UMLKSK CUI: C0206062
HumanACE259272angiotensin I converting enzyme 2
INFERRED, Score=800, UMLKSK CUI: C0206062
HumanBTNL256244butyrophilin-like 2 (MHC class II associated)
img OMIM, Score=1000, UMLKSK CUI: C0206062
HumanROBO454538roundabout, axon guidance receptor, homolog 4 (Drosophila)
INFERRED, Score=800, UMLKSK CUI: C0206062
HumanIL23A51561interleukin 23, alpha subunit p19
INFERRED, Score=800, UMLKSK CUI: C0206062
HumanCD20750489CD207 molecule, langerin
INFERRED, Score=800, UMLKSK CUI: C0206062
HumanCD20930835CD209 molecule
INFERRED, Score=800, UMLKSK CUI: C0206062
HumanSLC40A130061solute carrier family 40 (iron-regulated transporter), member 1
INFERRED, Score=800, UMLKSK CUI: C0206062
HumanTINF226277TERF1 (TRF1)-interacting nuclear factor 2
INFERRED, Score=800, UMLKSK CUI: C0206062
HumanHEY123462hairy/enhancer-of-split related with YRPW motif 1
INFERRED, Score=800, UMLKSK CUI: C0206062
HumanCOL4A3BP10087collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
INFERRED, Score=800, UMLKSK CUI: C0206062
HumanSLIT29353slit homolog 2 (Drosophila)
INFERRED, Score=800, UMLKSK CUI: C0206062
HumanCD1639332CD163 molecule
INFERRED, Score=800, UMLKSK CUI: C0206062
HumanCFLAR8837CASP8 and FADD-like apoptosis regulator
INFERRED, Score=800, UMLKSK CUI: C0206062
HumanFADD8772Fas (TNFRSF6)-associated via death domain
INFERRED, Score=800, UMLKSK CUI: C0206062
HumanAP3B18546adaptor-related protein complex 3, beta 1 subunit
INFERRED, Score=800, UMLKSK CUI: C0206062
HumanSCGB1A17356secretoglobin, family 1A, member 1 (uteroglobin)
INFERRED, Score=800, UMLKSK CUI: C0206062
HumanTP537157tumor protein p53
INFERRED, Score=800, UMLKSK CUI: C0206062
HumanTNFRSF1B7133tumor necrosis factor receptor superfamily, member 1B
INFERRED, Score=800, UMLKSK CUI: C0206062
HumanTNF7124tumor necrosis factor
INFERRED, Score=800, UMLKSK CUI: C0206062
HumanTIMP17076TIMP metallopeptidase inhibitor 1
INFERRED, Score=800, UMLKSK CUI: C0206062
HumanTGFB17040transforming growth factor, beta 1
INFERRED, Score=800, UMLKSK CUI: C0206062
HumanTERT7015telomerase reverse transcriptase
INFERRED, Score=800, UMLKSK CUI: C0206062
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0206062Lung Diseases, Interstitial0self