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Details
Link-It Detail - Disease - Fibroadenoma of breast
Debug Stats
  • ### Total Build Time: 82 ms 38.129 KB
  • CONCEPT_NAME gt=5 ms Completed: 5 ms rowSize= 342 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 642 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=39 ms Completed: 39 ms rowSize= 9.904 KB
  • CONCEPT_GENES gt=30 ms Completed: 30 ms rowSize= 26.037 KB
  • CONCEPT_XREFS gt=7 ms Completed: 7 ms rowSize= 1.156 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Fibroadenoma of breast C0178421
Definition (1)
A benign tumor of the breast characterized by the presence of stromal and epithelial elements. It presents as a painless, solitary, slow growing, firm, and mobile mass. It is the most common benign breast lesion. It usually occurs in women of childbearing age. The majority of fibroadenomas do not recur after complete excision. A slightly increased risk of developing cancer within fibroadenomas or in the breast tissue of patients previously treated for fibroadenomas has been reported.
Relationships (20)

Relation Types:
diso_​to_​anat : 8
diso_​to_​diso : 12


Relationships:
is_​abnormal_​cell_​of_​disease : 2
is_​associated_​anatomic_​site_​of : 1
is_​finding_​of_​disease : 4
is_​normal_​cell_​origin_​of_​disease : 2
is_​normal_​tissue_​origin_​of_​disease : 3
is_​not_​finding_​of_​disease : 1
isa : 5
may_​be_​finding_​of_​disease : 2
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Body tissue C0040300
DISO_to_ANATis_associated_anatomic_site_ofimg Breast C0006141
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Cell, Stromal C0162597
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Cells C0007634
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Lactiferous terminal bud C0929369
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg Mammary Gland Parenchyma C1521747
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Stromal Cell C1514104
DISO_to_DISOisaimg BREAST, FIBROADENOMA, INTRACANALICULAR C0334496
DISO_to_DISOis_finding_of_diseaseimg Biphasic Pattern C1332555
DISO_to_DISOmay_be_finding_of_diseaseimg Calcification C1533591
DISO_to_DISOisaimg Cellular Fibroadenoma C0346158
DISO_to_DISOisaimg Complex Fibroadenoma C1333137
DISO_to_DISOis_finding_of_diseaseimg Epithelial Component Present C1707933
DISO_to_DISOisaimg Giant fibroadenoma of breast C0346157
DISO_to_DISOis_not_finding_of_diseaseimg Malignant Glandular Epithelium Resembling the Normal Endometrium Present C1881556
DISO_to_DISOis_finding_of_diseaseimg Mesenchymal Component Present C1708981
DISO_to_DISOis_finding_of_diseaseimg Mixed Cellular Population C1513363
DISO_to_DISOisaimg Pericanalicular Breast Fibroadenoma C0334497
DISO_to_DISOmay_be_finding_of_diseaseimg Slow Growing Painless Mass C1710108
Genes (21)

Species:
human : 21
SpeciesGeneGeneIdGene NameEvidence
HumanTP638626tumor protein p63
img NCI, Score=801, Pubmed Id: 12203858, UMLKSK CUI: C0178421
HumanHMGA28091high mobility group AT-hook 2
img NCI, Score=801, Pubmed Id: 8739083, UMLKSK CUI: C0178421
HumanSCG27857secretogranin II
img NCI, Score=801, Pubmed Id: 11696168, UMLKSK CUI: C0178421
HumanTIMP27077TIMP metallopeptidase inhibitor 2
img NCI, Score=801, Pubmed Id: 8766524, UMLKSK CUI: C0178421
HumanTIMP17076TIMP metallopeptidase inhibitor 1
img NCI, Score=801, Pubmed Id: 8766524, UMLKSK CUI: C0178421
HumanSRD5A26716steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
img NCI, Score=801, Pubmed Id: 16608396, UMLKSK CUI: C0178421
HumanSNCG6623synuclein, gamma (breast cancer-specific protein 1)
img NCI, Score=801, Pubmed Id: 14504205, UMLKSK CUI: C0178421
HumanRHEB6009Ras homolog enriched in brain
img GENERIF, Score=1000, Pubmed Id: 18324915, UMLKSK CUI: C0178421
HumanPZP5858pregnancy-zone protein
img NCI, Score=801, Pubmed Id: 1700464, UMLKSK CUI: C0178421
HumanPTEN5728phosphatase and tensin homolog
img OMIM, Score=1000, UMLKSK CUI: C0178421
HumanPPP2CA5515protein phosphatase 2, catalytic subunit, alpha isozyme
img NCI, Score=801, Pubmed Id: 9066738, UMLKSK CUI: C0178421
HumanNME14830NME/NM23 nucleoside diphosphate kinase 1
img NCI, Score=801, Pubmed Id: 15604068, UMLKSK CUI: C0178421
img NCI, Score=801, Pubmed Id: 15604068, UMLKSK CUI: C0178421
img NCI, Score=801, Pubmed Id: 15604068, UMLKSK CUI: C0178421
HumanKRT163868keratin 16
img NCI, Score=801, Pubmed Id: 2458830, UMLKSK CUI: C0178421
HumanINHBA3624inhibin, beta A
img GENERIF, Score=1000, Pubmed Id: 15451571, UMLKSK CUI: C0178421
HumanHIF1A3091hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
img NCI, Score=801, Pubmed Id: 16080559, UMLKSK CUI: C0178421
HumanGJA12697gap junction protein, alpha 1, 43kDa
img GENERIF, Score=1000, Pubmed Id: 15948121, UMLKSK CUI: C0178421
HumanFGF12246fibroblast growth factor 1 (acidic)
img NCI, Score=801, Pubmed Id: 9756721, UMLKSK CUI: C0178421
img NCI, Score=801, Pubmed Id: 9756721, UMLKSK CUI: C0178421
HumanERBB22064v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
img GENERIF, Score=734, Pubmed Id: 18090908, UMLKSK CUI: C0178421
HumanEIF4EBP11978eukaryotic translation initiation factor 4E binding protein 1
img NCI, Score=801, Pubmed Id: 15501954, UMLKSK CUI: C0178421
HumanCTAG1B1485cancer/testis antigen 1B
img NCI, Score=801, Pubmed Id: 15026363, UMLKSK CUI: C0178421
HumanBMPR1A657bone morphogenetic protein receptor, type IA
img OMIM, Score=1000, UMLKSK CUI: C0178421
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0178421Fibroadenoma of breast0self