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Details
Link-It Detail - Disease - Cholesteatoma, Middle Ear
Debug Stats
  • ### Total Build Time: 26 ms 34.468 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 402 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 419 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=2 ms Completed: 2 ms rowSize= 979 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 2.775 KB
  • CONCEPT_RELATIONSHIPS gt=10 ms Completed: 10 ms rowSize= 12.752 KB
  • CONCEPT_GENES gt=8 ms Completed: 8 ms rowSize= 15.805 KB
  • CONCEPT_XREFS gt=3 ms Completed: 3 ms rowSize= 1.159 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
Cholesteatoma, Middle Ear C0155490
Middle Ear Cholesteatoma
Definition (1)
A mass of KERATIN-producing squamous EPITHELIUM that resembles an inverted (suck-in) bag of skin in the MIDDLE EAR. It arises from the eardrum (TYMPANIC MEMBRANE) and grows into the MIDDLE EAR causing erosion of EAR OSSICLES and MASTOID that contains the INNER EAR.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (2)
img Cholesteatoma C0008373
img Ear Diseases C0013447
Ancestral Roots
RootRoot Plus OneDepthParent
img Skin and Connective Tissue Diseases C0175166img Skin Diseases C00372745img Cholesteatoma C0008373
img Otorhinolaryngologic Diseases C0029896img Ear Diseases C00134473img Ear Diseases C0013447
Relationships (40)

Relation Types:
diso_​to_​anat : 15
diso_​to_​diso : 23
diso_​to_​phen : 1
diso_​to_​phys : 1


Relationships:
none : 30
classifies : 1
is_​associated_​anatomic_​site_​of : 3
isa : 4
mapped_​to : 1
permuted_​term_​of : 1
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO87img Complication Aspects C1171258
DISO_to_DISO65img Complication Aspects C1171258
DISO_to_DISO59img Otitis Media C0029882
DISO_to_ANAT56img Mastoid C0446908
DISO_to_DISO47img Otitis Media C0029882
DISO_to_ANAT42img Mastoid C0446908
DISO_to_ANAT31img Ear, Middle C0013455
DISO_to_ANAT28img Ear, Middle C0013455
DISO_to_ANAT24img Ear Canal C0013444
DISO_to_ANAT22img Tympanic Membrane C0041445
DISO_to_DISO22img COMPL POSTOP C0032787
DISO_to_DISO21img Fistula C0016169
DISO_to_DISO21img Otitis Media, Suppurative C0029888
DISO_to_ANAT20img Ear Canal C0013444
DISO_to_PHEN20img genetic aspects C0017399
DISO_to_ANAT18img Temporal Bone C0039484
DISO_to_ANAT16img Ear Ossicles C0013450
DISO_to_DISO15img Labyrinth Diseases C0022890
DISO_to_ANAT14img Tympanic Membrane C0041445
DISO_to_DISO14img COMPL POSTOP C0032787
DISO_to_ANAT12img Petrous Bone C0031266
DISO_to_ANAT11img Cartilage C0007301
DISO_to_DISO10img Ear Diseases C0013447
DISO_to_DISO10img Mastoiditis C0024904
DISO_to_DISO10img Otitis Media with Effusion C0029883
Genes (9)

Species:
human : 9
SpeciesGeneGeneIdGene NameEvidence
HumanSLC3A26520solute carrier family 3 (amino acid transporter heavy chain), member 2
img NCI, Score=801, Pubmed Id: 8369083, UMLKSK CUI: C0155490
HumanS100A86279S100 calcium binding protein A8
img NCI, Score=801, Pubmed Id: 7888019, UMLKSK CUI: C0155490
HumanPGF5228placental growth factor
img GENERIF, Score=1000, Pubmed Id: 16864484, UMLKSK CUI: C0155490
HumanIVL3713involucrin
img NCI, Score=801, Pubmed Id: 2683803, UMLKSK CUI: C0155490
img NCI, Score=801, Pubmed Id: 2683803, UMLKSK CUI: C0155490
img NCI, Score=801, Pubmed Id: 10406309, UMLKSK CUI: C0155490
HumanICAM23384intercellular adhesion molecule 2
img NCI, Score=801, Pubmed Id: 7526720, UMLKSK CUI: C0155490
HumanEGF1950epidermal growth factor
img GENERIF, Score=1000, Pubmed Id: 15481560, UMLKSK CUI: C0155490
HumanDEFB4A1673defensin, beta 4A
img NCI, Score=801, Pubmed Id: 12701748, UMLKSK CUI: C0155490
img NCI, Score=801, Pubmed Id: 16001900, UMLKSK CUI: C0155490
img NCI, Score=801, Pubmed Id: 16001900, UMLKSK CUI: C0155490
img NCI, Score=801, Pubmed Id: 16001900, UMLKSK CUI: C0155490
img NCI, Score=801, Pubmed Id: 16001900, UMLKSK CUI: C0155490
img NCI, Score=801, Pubmed Id: 16001900, UMLKSK CUI: C0155490
HumanBCL2L1598BCL2-like 1
img NCI, Score=801, Pubmed Id: 10406309, UMLKSK CUI: C0155490
img NCI, Score=801, Pubmed Id: 10406309, UMLKSK CUI: C0155490
HumanANXA2302annexin A2
img NCI, Score=801, Pubmed Id: 9527111, UMLKSK CUI: C0155490
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0155490Cholesteatoma, Middle Ear0self