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Details
Link-It Detail - Disease - Proliferative diabetic retinopathy
Debug Stats
  • ### Total Build Time: 132 ms 29.523 KB
  • CONCEPT_NAME gt=12 ms Completed: 12 ms rowSize= 366 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 407 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=83 ms Completed: 83 ms rowSize= 8.342 KB
  • CONCEPT_GENES gt=29 ms Completed: 29 ms rowSize= 19.188 KB
  • CONCEPT_XREFS gt=6 ms Completed: 6 ms rowSize= 1.168 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Proliferative diabetic retinopathy C0154830
Definition (1)
Advanced retinopathy due to diabetes mellitus characterized by the formation of new vessels in the retina. The new vessels are abnormal and fragile. If hemorrhage occurs due to the vascular fragility, there is increased risk of vision loss or blindness.
Relationships (18)

Relation Types:
diso_​to_​anat : 4
diso_​to_​diso : 14


Relationships:
associated_​with : 1
classifies : 2
clinically_​similar : 1
is_​associated_​anatomic_​site_​of : 4
isa : 9
mapped_​to : 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_associated_anatomic_site_ofimg Cardiovascular System C0007226
DISO_to_ANATis_associated_anatomic_site_ofimg Eye C0015392
DISO_to_ANATis_associated_anatomic_site_ofimg Retina C0035298
DISO_to_ANATis_associated_anatomic_site_ofimg Vascular System C0489903
DISO_to_DISOassociated_withimg Diabetes Mellitus C0011849
DISO_to_DISOclinically_similarimg Diabetic Retinopathy C0011884
DISO_to_DISOisaimg Early PDR C0730279
DISO_to_DISOisaimg High risk PDR C0730280
DISO_to_DISOisaimg Non-high risk PDR with CSME C1275954
DISO_to_DISOisaimg Non-high-risk PDR with no macular edema C1275414
DISO_to_DISOisaimg O/E - left eye proliferative diabetic retinopathy C1319542
DISO_to_DISOisaimg O/E - right eye proliferative diabetic retinopathy C1319541
DISO_to_DISOclassifiesimg Other retinal disorders C0339438
DISO_to_DISOisaimg PDR - NVD C0339474
DISO_to_DISOisaimg PDR - NVE C0339475
DISO_to_DISOisaimg PDR iris neovascularisation C0730282
DISO_to_DISOmapped_toimg Proliferative diabetic retinopathy C0154830
DISO_to_DISOclassifiesimg Retinal detachments; defects; vascular occlusion; and retinopathy C0809995
Genes (15)

Species:
human : 15
SpeciesGeneGeneIdGene NameEvidence
HumanVEGFA7422vascular endothelial growth factor A
img GENERIF, Score=1000, Pubmed Id: 18682813, UMLKSK CUI: C0154830
img GENERIF, Score=1000, Pubmed Id: 12453985, UMLKSK CUI: C0154830
img GENERIF, Score=1000, Pubmed Id: 14988276, UMLKSK CUI: C0154830
HumanTNF7124tumor necrosis factor
img GENERIF, Score=1000, Pubmed Id: 18413212, UMLKSK CUI: C0154830
HumanCCL26347chemokine (C-C motif) ligand 2
img GENERIF, Score=1000, Pubmed Id: 16730843, UMLKSK CUI: C0154830
HumanPGF5228placental growth factor
img GENERIF, Score=1000, Pubmed Id: 12453985, UMLKSK CUI: C0154830
HumanNFKB14790nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
img GENERIF, Score=1000, Pubmed Id: 12743697, UMLKSK CUI: C0154830
HumanMMP94318matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
img GENERIF, Score=1000, Pubmed Id: 18552985, UMLKSK CUI: C0154830
HumanMME4311membrane metallo-endopeptidase
img GENERIF, Score=1000, Pubmed Id: 16943769, UMLKSK CUI: C0154830
HumanIL63569interleukin 6 (interferon, beta 2)
img GENERIF, Score=1000, Pubmed Id: 18988929, UMLKSK CUI: C0154830
HumanICAM13383intercellular adhesion molecule 1
img GENERIF, Score=1000, Pubmed Id: 18942221, UMLKSK CUI: C0154830
HumanFGF22247fibroblast growth factor 2 (basic)
img GENERIF, Score=1000, Pubmed Id: 18279437, UMLKSK CUI: C0154830
img GENERIF, Score=1000, Pubmed Id: 17997184, UMLKSK CUI: C0154830
HumanEPO2056erythropoietin
img GENERIF, Score=1000, Pubmed Id: 16123502, UMLKSK CUI: C0154830
img GENERIF, Score=1000, Pubmed Id: 18458324, UMLKSK CUI: C0154830
HumanCTGF1490connective tissue growth factor
img GENERIF, Score=1000, Pubmed Id: 14988298, UMLKSK CUI: C0154830
HumanCORT1325cortistatin
img GENERIF, Score=1000, Pubmed Id: 16043736, UMLKSK CUI: C0154830
HumanALDRL2233
img GENERIF, Score=1000, Pubmed Id: 17563730, UMLKSK CUI: C0154830
HumanAGER177advanced glycosylation end product-specific receptor
img GENERIF, Score=1000, Pubmed Id: 17560613, UMLKSK CUI: C0154830
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0154830Proliferative diabetic retinopathy0self