Genes (23)
Species: human : 23 | |
Human | PPP1R13L | 10848 | protein phosphatase 1, regulatory subunit 13 like | neither polymorphisms in several DNA repair genes nor alleles of several polymorphisms in the chromosomal of region 19q13.2-3, encompassing the genes ASE, ERCC1, RAI and XPD, were associated with risk of testicular cancer in Danish patients | Human | KDM5B | 10765 | lysine (K)-specific demethylase 5B | Our results suggest that the PLU-1 protein may belong to the class of testis/cancer antigens. | Human | RAI1 | 10743 | retinoic acid induced 1 | Title:Polymorphisms in RAI and in genes of nucleotide and base excision repair are not associated with risk of testicular cancer.|Association:Not Found|Conclusion:To our knowledge this is the first study of DNA repair gene polymorphisms and risk of testicular cancer. | Human | BCL10 | 8915 | B-cell CLL/lymphoma 10 | Title:|Association:Not Found|Conclusion:Not Found | Human | TFRC | 7037 | transferrin receptor (p90, CD71) | Transferrin receptor expression in testis cancer. | Human | SELL | 6402 | selectin L | The yield of CD34+ PBPC and colony-forming units-granulocyte-macrophage (CFU-GM) in leukapheresis products and the expression of the adhesion molecules CD11a, CD31, CD49d, CD49e, CD54, CD58, CD62L, c-kit (CD117), Thy-1 (CD90), CD33, CD38, and HLA-DR on CD34+ PBPC were analyzed in patients with cancer of the testis (n = 10), breast cancer (n = 10), Hodgkins disease (n = 20), high-grade (n = 20) and low-grade (n = 20) non-Hodgkins lymphoma, and healthy donors (n = 20) undergoing G-CSF (filgrastim)-stimulated PBPC mobilization. | Human | RELA | 5970 | v-rel avian reticuloendotheliosis viral oncogene homolog A | Title:Polymorphisms in RAI and in genes of nucleotide and base excision repair are not associated with risk of testicular cancer.|Association:Not Found|Conclusion:To our knowledge this is the first study of DNA repair gene polymorphisms and risk of testicular cancer. | Human | MGMT | 4255 | O-6-methylguanine-DNA methyltransferase | inactivation of MGMT contributes to development of nonseminomatous testicular cancer | Human | KIT | 3815 | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | The yield of CD34+ PBPC and colony-forming units-granulocyte-macrophage (CFU-GM) in leukapheresis products and the expression of the adhesion molecules CD11a, CD31, CD49d, CD49e, CD54, CD58, CD62L, c-kit (CD117), Thy-1 (CD90), CD33, CD38, and HLA-DR on CD34+ PBPC were analyzed in patients with cancer of the testis (n = 10), breast cancer (n = 10), Hodgkins disease (n = 20), high-grade (n = 20) and low-grade (n = 20) non-Hodgkins lymphoma, and healthy donors (n = 20) undergoing G-CSF (filgrastim)-stimulated PBPC mobilization. | Human | ITGAL | 3683 | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) | The yield of CD34+ PBPC and colony-forming units-granulocyte-macrophage (CFU-GM) in leukapheresis products and the expression of the adhesion molecules CD11a, CD31, CD49d, CD49e, CD54, CD58, CD62L, c-kit (CD117), Thy-1 (CD90), CD33, CD38, and HLA-DR on CD34+ PBPC were analyzed in patients with cancer of the testis (n = 10), breast cancer (n = 10), Hodgkin;s disease (n = 20), high-grade (n = 20) and low-grade (n = 20) non-Hodgkin;s lymphoma, and healthy donors (n = 20) undergoing G-CSF (filgrastim)-stimulated PBPC mobilization. | Human | ITGA4 | 3676 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | The yield of CD34+ PBPC and colony-forming units-granulocyte-macrophage (CFU-GM) in leukapheresis products and the expression of the adhesion molecules CD11a, CD31, CD49d, CD49e, CD54, CD58, CD62L, c-kit (CD117), Thy-1 (CD90), CD33, CD38, and HLA-DR on CD34+ PBPC were analyzed in patients with cancer of the testis (n = 10), breast cancer (n = 10), Hodgkin;s disease (n = 20), high-grade (n = 20) and low-grade (n = 20) non-Hodgkin;s lymphoma, and healthy donors (n = 20) undergoing G-CSF (filgrastim)-stimulated PBPC mobilization. Correspondingly, expression of CD49d on CD34+ PBPC was significantly lower in the same patients with cancer of the testis compared with high-grade and low-grade non-Hodgkin;s lymphoma and Hodgkins; disease and in patients with breast cancer compared with high-grade and low-grade non-Hodgkin;s lymphoma, Hodgkins;s disease, and healthy donors. | Human | INSL3 | 3640 | insulin-like 3 (Leydig cell) | In two unilaterally orchiectomized former testis cancer patients, who underwent hCG stimulation test, INSL3 serum levels were unchanged 72 and 96 h after hCG stimulation. | Human | IGF1R | 3480 | insulin-like growth factor 1 receptor | Luteolin inhibits IGF-1R/AKT signaling, these results provideing a new insight into the mechanisms that luteolin inhibits testicular cancer cells | Human | ERCC2 | 2068 | excision repair cross-complementing rodent repair deficiency, complementation group 2 | Title:Polymorphisms in RAI and in genes of nucleotide and base excision repair are not associated with risk of testicular cancer.|Association:Not Found|Conclusion:To our knowledge this is the first study of DNA repair gene polymorphisms and risk of testicular cancer. | Human | CYP3A5 | 1577 | cytochrome P450, family 3, subfamily A, polypeptide 5 | Title:Single nucleotide polymorphisms and haplotype frequencies of CYP3A5 in a Japanese population|Association:Not Found|Conclusion:Our findings suggest that CYP3A5*3 is the major defective allele and that other functional exonic SNPs are rare in the Japanese. Title:|Association:Not Found|Conclusion:Not Found Title:|Association:Not Found|Conclusion:Not Found | Human | CYP3A4 | 1576 | cytochrome P450, family 3, subfamily A, polypeptide 4 | Title:|Association:Not Found|Conclusion:Not Found Title:Screening of 12 SNPs of CYP3A4 in a Chinese population using oligonucleotide microarray.|Association:Not Found|Conclusion:The genotyping results of the 18 heterozygous subjects and 12 wild-type subjects were validated by direct sequencing. Title:|Association:Not Found|Conclusion:Not Found | Human | CYP1B1 | 1545 | cytochrome P450, family 1, subfamily B, polypeptide 1 | Title:|Association:Not Found|Conclusion:Not Found | Human | CYP1A2 | 1544 | cytochrome P450, family 1, subfamily A, polypeptide 2 | decrease in activity is associated with testicular cancer Title:|Association:Not Found|Conclusion:Not Found | Human | CYP1A1 | 1543 | cytochrome P450, family 1, subfamily A, polypeptide 1 | in testicular cancer two nonredundant SNPs in CYP1A1 (cytochrome P450 family 1 subfamily A polypeptide) were inversely associated with nonseminoma: CYP1A1 promoter SNP rs4886605 and rs2606345 intron 1 SNP | Human | CD38 | 952 | CD38 molecule | The yield of CD34+ PBPC and colony-forming units-granulocyte-macrophage (CFU-GM) in leukapheresis products and the expression of the adhesion molecules CD11a, CD31, CD49d, CD49e, CD54, CD58, CD62L, c-kit (CD117), Thy-1 (CD90), CD33, CD38, and HLA-DR on CD34+ PBPC were analyzed in patients with cancer of the testis (n = 10), breast cancer (n = 10), Hodgkins disease (n = 20), high-grade (n = 20) and low-grade (n = 20) non-Hodgkins lymphoma, and healthy donors (n = 20) undergoing G-CSF (filgrastim)-stimulated PBPC mobilization. | Human | CD33 | 945 | CD33 molecule | The yield of CD34+ PBPC and colony-forming units-granulocyte-macrophage (CFU-GM) in leukapheresis products and the expression of the adhesion molecules CD11a, CD31, CD49d, CD49e, CD54, CD58, CD62L, c-kit (CD117), Thy-1 (CD90), CD33, CD38, and HLA-DR on CD34+ PBPC were analyzed in patients with cancer of the testis (n = 10), breast cancer (n = 10), Hodgkin;s disease (n = 20), high-grade (n = 20) and low-grade (n = 20) non-Hodgkin;s lymphoma, and healthy donors (n = 20) undergoing G-CSF (filgrastim)-stimulated PBPC mobilization. | Human | ALOX5 | 240 | arachidonate 5-lipoxygenase | increased expressions of 5-LOX and 12-LOX were detected in testicular cancer tissues | Human | ALOX12 | 239 | arachidonate 12-lipoxygenase | increased expressions of 5-LOX and 12-LOX were detected in testicular cancer tissues |
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