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Details
Link-It Detail - Disease - Malignant neoplasm of testis
Debug Stats
  • ### Total Build Time: 18 ms 34.320 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 354 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 1.095 KB
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=12 ms Completed: 12 ms rowSize= 31.544 KB
  • CONCEPT_XREFS gt=3 ms Completed: 3 ms rowSize= 1.162 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Malignant neoplasm of testis C0153594
Definition (1)

Testicular cancer forms in a man's testicles, the two egg-shaped glands that produce sperm and testosterone. Testicular cancer mainly affects young men between the ages of 20 and 39. It is also more common in men who

  • Have had abnormal testicle development
  • Have had an undescended testicle
  • Have a family history of the cancer

Symptoms include pain, swelling or lumps in your testicles or groin area. Most cases can be treated, especially if it is found early. Treatment options include surgery, radiation and/or chemotherapy. Regular exams after treatment are important. Treatments may also cause infertility. If you may want children later on, you should consider sperm banking before treatment.

NIH: National Cancer Institute

Genes (23)

Species:
human : 23
SpeciesGeneGeneIdGene NameEvidence
HumanPPP1R13L10848protein phosphatase 1, regulatory subunit 13 like
img GENERIF, Score=1000, Pubmed Id: 15885892, UMLKSK CUI: C0153594
HumanKDM5B10765lysine (K)-specific demethylase 5B
img NCI, Score=801, Pubmed Id: 12237901, UMLKSK CUI: C0153594
HumanRAI110743retinoic acid induced 1
img GAD, Score=1000, Pubmed Id: 15885892, UMLKSK CUI: C0153594
HumanBCL108915B-cell CLL/lymphoma 10
img GAD, Score=1000, Pubmed Id: 16229939, UMLKSK CUI: C0153594
HumanTFRC7037transferrin receptor (p90, CD71)
img NCI, Score=801, Pubmed Id: 8145279, UMLKSK CUI: C0153594
HumanSELL6402selectin L
img NCI, Score=801, Pubmed Id: 10791904, UMLKSK CUI: C0153594
HumanRELA5970v-rel avian reticuloendotheliosis viral oncogene homolog A
img GAD, Score=1000, Pubmed Id: 15885892, UMLKSK CUI: C0153594
HumanMGMT4255O-6-methylguanine-DNA methyltransferase
img GENERIF, Score=901, Pubmed Id: 12483540, UMLKSK CUI: C0153594
HumanKIT3815v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
img NCI, Score=801, Pubmed Id: 10791904, UMLKSK CUI: C0153594
HumanITGAL3683integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
img NCI, Score=801, Pubmed Id: 10791904, UMLKSK CUI: C0153594
HumanITGA43676integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
img NCI, Score=801, Pubmed Id: 10791904, UMLKSK CUI: C0153594
img NCI, Score=801, Pubmed Id: 10791904, UMLKSK CUI: C0153594
HumanINSL33640insulin-like 3 (Leydig cell)
img NCI, Score=801, Pubmed Id: 15755855, UMLKSK CUI: C0153594
HumanIGF1R3480insulin-like growth factor 1 receptor
img GENERIF, Score=734, Pubmed Id: 17065200, UMLKSK CUI: C0153594
HumanERCC22068excision repair cross-complementing rodent repair deficiency, complementation group 2
img GAD, Score=1000, Pubmed Id: 15885892, UMLKSK CUI: C0153594
HumanCYP3A51577cytochrome P450, family 3, subfamily A, polypeptide 5
img GAD, Score=1000, Pubmed Id: 14961555, UMLKSK CUI: C0153594
img GAD, Score=1000, Pubmed Id: 16172230, UMLKSK CUI: C0153594
img GAD, Score=1000, Pubmed Id: 16207150, UMLKSK CUI: C0153594
HumanCYP3A41576cytochrome P450, family 3, subfamily A, polypeptide 4
img GAD, Score=1000, Pubmed Id: 16172230, UMLKSK CUI: C0153594
img GAD, Score=1000, Pubmed Id: 15684873, UMLKSK CUI: C0153594
img GAD, Score=1000, Pubmed Id: 16207150, UMLKSK CUI: C0153594
HumanCYP1B11545cytochrome P450, family 1, subfamily B, polypeptide 1
img GAD, Score=1000, Pubmed Id: 16172230, UMLKSK CUI: C0153594
HumanCYP1A21544cytochrome P450, family 1, subfamily A, polypeptide 2
img GENERIF, Score=1000, Pubmed Id: 14976127, UMLKSK CUI: C0153594
img GAD, Score=1000, Pubmed Id: 16172230, UMLKSK CUI: C0153594
HumanCYP1A11543cytochrome P450, family 1, subfamily A, polypeptide 1
img GENERIF, Score=673, Pubmed Id: 18415690, UMLKSK CUI: C0153594
HumanCD38952CD38 molecule
img NCI, Score=801, Pubmed Id: 10791904, UMLKSK CUI: C0153594
HumanCD33945CD33 molecule
img NCI, Score=801, Pubmed Id: 10791904, UMLKSK CUI: C0153594
HumanALOX5240arachidonate 5-lipoxygenase
img GENERIF, Score=734, Pubmed Id: 14767568, UMLKSK CUI: C0153594
HumanALOX12239arachidonate 12-lipoxygenase
img GENERIF, Score=734, Pubmed Id: 14767568, UMLKSK CUI: C0153594
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0153594Malignant neoplasm of testis0self