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Details
Link-It Detail - Disease - Malignant neoplasm of gallbladder
Debug Stats
  • ### Total Build Time: 22 ms 34.539 KB
  • CONCEPT_NAME gt=8 ms Completed: 8 ms rowSize= 364 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 1.177 KB
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=11 ms Completed: 11 ms rowSize= 31.666 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.167 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Malignant neoplasm of gallbladder C0153452
Definition (1)

Your gallbladder is a pear-shaped organ under your liver. It stores bile, a fluid made by your liver to digest fat. As your stomach and intestines digest food, your gallbladder releases bile through a tube called the common bile duct. The duct connects your gallbladder and liver to your small intestine.

Cancer of the gallbladder is rare. It is more common in women and Native Americans. Symptoms include

  • Jaundice (yellowing of the skin and whites of the eyes)
  • Pain above the stomach
  • Fever
  • Nausea and vomiting
  • Bloating
  • Lumps in the abdomen

It is hard to diagnose gallbladder cancer in its early stages. Sometimes doctors find it when they remove the gallbladder for another reason. But people with gallstones rarely have gallbladder cancer. Because it is often found late, it can be hard to treat gallbladder cancer. Treatment options include surgery, chemotherapy, radiation or a combination.

NIH: National Cancer Institute

Genes (25)

Species:
human : 25
SpeciesGeneGeneIdGene NameEvidence
HumanSH3GLB151100SH3-domain GRB2-like endophilin B1
img GENERIF, Score=1000, Pubmed Id: 18752120, UMLKSK CUI: C0153452
HumanKEAP19817kelch-like ECH-associated protein 1
img GENERIF, Score=1000, Pubmed Id: 18692501, UMLKSK CUI: C0153452
HumanVEGFC7424vascular endothelial growth factor C
img GENERIF, Score=1000, Pubmed Id: 12469214, UMLKSK CUI: C0153452
HumanTP537157tumor protein p53
img GENERIF, Score=1000, Pubmed Id: 17531965, UMLKSK CUI: C0153452
img GENERIF, Score=1000, Pubmed Id: 16686942, UMLKSK CUI: C0153452
HumanTOP2A7153topoisomerase (DNA) II alpha 170kDa
img GENERIF, Score=901, Pubmed Id: 18824850, UMLKSK CUI: C0153452
HumanTNF7124tumor necrosis factor
img GENERIF, Score=1000, Pubmed Id: 18260730, UMLKSK CUI: C0153452
HumanTGFB17040transforming growth factor, beta 1
img GENERIF, Score=1000, Pubmed Id: 18571008, UMLKSK CUI: C0153452
img GENERIF, Score=861, Pubmed Id: 12579267, UMLKSK CUI: C0153452
HumanOGG149688-oxoguanine DNA glycosylase
img GENERIF, Score=734, Pubmed Id: 17417784, UMLKSK CUI: C0153452
HumanNFE2L24780nuclear factor, erythroid 2-like 2
img GENERIF, Score=1000, Pubmed Id: 18692501, UMLKSK CUI: C0153452
HumanMTHFR4524methylenetetrahydrofolate reductase (NAD(P)H)
img GENERIF, Score=1000, Pubmed Id: 17979520, UMLKSK CUI: C0153452
HumanMGMT4255O-6-methylguanine-DNA methyltransferase
img GENERIF, Score=861, Pubmed Id: 15809756, UMLKSK CUI: C0153452
HumanIL1RN3557interleukin 1 receptor antagonist
img GENERIF, Score=1000, Pubmed Id: 18940468, UMLKSK CUI: C0153452
HumanGSTT12952glutathione S-transferase theta 1
img GENERIF, Score=1000, Pubmed Id: 16760134, UMLKSK CUI: C0153452
HumanGALNT32591UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
img GENERIF, Score=1000, Pubmed Id: 15041730, UMLKSK CUI: C0153452
HumanESR22100estrogen receptor 2 (ER beta)
img GENERIF, Score=734, Pubmed Id: 15492781, UMLKSK CUI: C0153452
HumanERBB22064v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
img GENERIF, Score=1000, Pubmed Id: 16686942, UMLKSK CUI: C0153452
HumanEGF1950epidermal growth factor
img GENERIF, Score=1000, Pubmed Id: 18571008, UMLKSK CUI: C0153452
HumanCYP7A11581cytochrome P450, family 7, subfamily A, polypeptide 1
img GENERIF, Score=734, Pubmed Id: 18178499, UMLKSK CUI: C0153452
HumanCYP1A11543cytochrome P450, family 1, subfamily A, polypeptide 1
img GENERIF, Score=1000, Pubmed Id: 12071517, UMLKSK CUI: C0153452
img GENERIF, Score=1000, Pubmed Id: 18287863, UMLKSK CUI: C0153452
HumanCTNNB11499catenin (cadherin-associated protein), beta 1, 88kDa
img GENERIF, Score=901, Pubmed Id: 17341890, UMLKSK CUI: C0153452
HumanCTGF1490connective tissue growth factor
img GENERIF, Score=1000, Pubmed Id: 18451226, UMLKSK CUI: C0153452
HumanCDKN2A1029cyclin-dependent kinase inhibitor 2A
img GENERIF, Score=1000, Pubmed Id: 18081229, UMLKSK CUI: C0153452
HumanCDH1999cadherin 1, type 1, E-cadherin (epithelial)
img GENERIF, Score=1000, Pubmed Id: 12532418, UMLKSK CUI: C0153452
img GENERIF, Score=901, Pubmed Id: 11683173, UMLKSK CUI: C0153452
img GENERIF, Score=901, Pubmed Id: 17341890, UMLKSK CUI: C0153452
HumanAPOB338apolipoprotein B
img GAD, Score=1000, Pubmed Id: 14618390, UMLKSK CUI: C0153452
img GENERIF, Score=1000, Pubmed Id: 17696941, UMLKSK CUI: C0153452
img GENERIF, Score=1000, Pubmed Id: 14618390, UMLKSK CUI: C0153452
HumanNAT210N-acetyltransferase 2 (arylamine N-acetyltransferase)
img GENERIF, Score=1000, Pubmed Id: 17224641, UMLKSK CUI: C0153452
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0153452Malignant neoplasm of gallbladder0self