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Details
Link-It Detail - Disease - Acute leukemia
Debug Stats
  • ### Total Build Time: 73 ms 58.374 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 326 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 563 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=22 ms Completed: 22 ms rowSize= 11.253 KB
  • CONCEPT_GENES gt=48 ms Completed: 48 ms rowSize= 45.034 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.148 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Acute leukemia C0085669
Definition (1)
A clonal (malignant) hematopoietic disorder affecting the bone marrow and the peripheral blood. The malignant cells show minimal differentiation and are called blasts, either myeloid blasts (myeloblasts) or lymphoid blasts (lymphoblasts). According to the type of blasts present, acute leukemias are classified as acute myeloid leukemia (AML) and precursor lymphoblastic or acute lymphoblastic leukemia (ALL).
Relationships (22)

Relation Types:
diso_​to_​anat : 7
diso_​to_​diso : 13
diso_​to_​gene : 2


Relationships:
associated_​with : 1
classifies : 1
gene_​associated_​with_​disease : 2
is_​abnormal_​cell_​of_​disease : 3
is_​normal_​cell_​origin_​of_​disease : 1
is_​normal_​tissue_​origin_​of_​disease : 1
is_​not_​finding_​of_​disease : 2
is_​primary_​anatomic_​site_​of_​disease : 2
isa : 5
mapped_​to : 3
use : 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Bone Marrow C0005953
DISO_to_ANATis_normal_tissue_origin_of_diseaseimg HEMOLYMPHORETICULAR TISSUE C1512398
DISO_to_ANATis_primary_anatomic_site_of_diseaseimg Hematopoietic and Lymphatic System C1512394
DISO_to_ANATis_normal_cell_origin_of_diseaseimg Hematopoietic and Lymphoid Cell C1512385
DISO_to_ANATis_abnormal_cell_of_diseaseimg Leukemic Cell C1517806
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Cell C0597032
DISO_to_ANATis_abnormal_cell_of_diseaseimg Neoplastic Hematopoietic and Lymphoid Cell C1513983
DISO_to_DISOisaimg Act leuk uns cl w rmson C0686586
DISO_to_DISOisaimg Acute Leukemia of Ambiguous Lineage C1301357
DISO_to_DISOassociated_withimg Acute leukaemia, NOS, without mention of remission C0686587
DISO_to_DISOmapped_toimg Acute leukemia C0085669
DISO_to_DISOisaimg Acute lymphocytic leukemia C0023449
DISO_to_DISOisaimg Burkitt Lymphoma C0006413
DISO_to_DISOis_not_finding_of_diseaseimg Chronic Clinical Course C1333035
DISO_to_DISOmapped_toimg LEUKAEMIA NEONATAL C0235813
DISO_to_DISOclassifiesimg Leukemia C0023418
DISO_to_DISOisaimg Leukemia, Myelocytic, Acute C0023467
DISO_to_DISOuseimg Precursor T-Cell Lymphoblastic Leukemia-Lymphoma C1961099
DISO_to_DISOis_not_finding_of_diseaseimg Solid Growth Pattern C1336028
DISO_to_DISOmapped_toimg Undifferentiated leukemia C1378511
DISO_to_GENEgene_associated_with_diseaseimg TLX1 gene C0920270
DISO_to_GENEgene_associated_with_diseaseimg TLX1 wt Allele C1705271
Genes (251)

Species:
human : 244
mouse : 7
Page Size
Current 25
  Page 1 of 11
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
MouseLHX29355LIM homeobox 2
img NCI, Score=801, Pubmed Id: 14687986, UMLKSK CUI: C0085669
MouseCCL216366chemokine (C-C motif) ligand 21
img NCI, Score=801, Pubmed Id: 12172984, UMLKSK CUI: C0085669
MousePBX15087pre-B-cell leukemia homeobox 1
img NCI, Score=801, Pubmed Id: 8093327, UMLKSK CUI: C0085669
MouseMPL4352myeloproliferative leukemia virus oncogene
img NCI, Score=801, Pubmed Id: 2539212, UMLKSK CUI: C0085669
MouseAFF14299AF4/FMR2 family, member 1
img NCI, Score=801, Pubmed Id: 9365243, UMLKSK CUI: C0085669
MouseCDX41046caudal type homeobox 4
img NCI, Score=801, Pubmed Id: 17068127, UMLKSK CUI: C0085669
MouseCD80941CD80 molecule
img NCI, Score=801, Pubmed Id: 10918502, UMLKSK CUI: C0085669
HumanPPBPL1728045
img NCI, Score=801, Pubmed Id: 6158265, UMLKSK CUI: C0085669
img NCI, Score=801, Pubmed Id: 6180502, UMLKSK CUI: C0085669
img NCI, Score=801, Pubmed Id: 6158265, UMLKSK CUI: C0085669
HumanLOC644165644165
img NCI, Score=801, Pubmed Id: 2678002, UMLKSK CUI: C0085669
img NCI, Score=801, Pubmed Id: 1993310, UMLKSK CUI: C0085669
HumanFLJ42953400892
img NCI, Score=801, Pubmed Id: 2678002, UMLKSK CUI: C0085669
img NCI, Score=801, Pubmed Id: 3172840, UMLKSK CUI: C0085669
img NCI, Score=801, Pubmed Id: 1993310, UMLKSK CUI: C0085669
HumanP2RY8286530purinergic receptor P2Y, G-protein coupled, 8
img GENERIF, Score=1000, Pubmed Id: 17487742, UMLKSK CUI: C0085669
HumanFRYL285527FRY-like
img GENERIF, Score=861, Pubmed Id: 17854671, UMLKSK CUI: C0085669
HumanPIKFYVE200576phosphoinositide kinase, FYVE finger containing
img NCI, Score=801, Pubmed Id: 2976295, UMLKSK CUI: C0085669
HumanZNF384171017zinc finger protein 384
Click here to display 7 evidence detail records.
HumanFAM123B139285
img GENERIF, Score=694, Pubmed Id: 18452086, UMLKSK CUI: C0085669
HumanLRRC3B116135leucine rich repeat containing 3B
img NCI, Score=801, Pubmed Id: 14706139, UMLKSK CUI: C0085669
img NCI, Score=801, Pubmed Id: 15840217, UMLKSK CUI: C0085669
HumanSLC22A1685413solute carrier family 22 (organic cation/carnitine transporter), member 16
img NCI, Score=801, Pubmed Id: 15963465, UMLKSK CUI: C0085669
HumanBAALC79870brain and acute leukemia, cytoplasmic
img NCI, Score=801, Pubmed Id: 11707601, UMLKSK CUI: C0085669
img NCI, Score=801, Pubmed Id: 14585369, UMLKSK CUI: C0085669
img NCI, Score=801, Pubmed Id: 11707601, UMLKSK CUI: C0085669
img NCI, Score=801, Pubmed Id: 11707601, UMLKSK CUI: C0085669
HumanNOM164434nucleolar protein with MIF4G domain 1
img NCI, Score=801, Pubmed Id: 15715967, UMLKSK CUI: C0085669
img NCI, Score=801, Pubmed Id: 15715967, UMLKSK CUI: C0085669
HumanNOD264127nucleotide-binding oligomerization domain containing 2
img GENERIF, Score=1000, Pubmed Id: 17724347, UMLKSK CUI: C0085669
HumanAVEN57099apoptosis, caspase activation inhibitor
img NCI, Score=801, Pubmed Id: 12853345, UMLKSK CUI: C0085669
img NCI, Score=801, Pubmed Id: 12853345, UMLKSK CUI: C0085669
HumanDIABLO56616diablo, IAP-binding mitochondrial protein
img NCI, Score=801, Pubmed Id: 15505413, UMLKSK CUI: C0085669
img NCI, Score=801, Pubmed Id: 11964312, UMLKSK CUI: C0085669
img NCI, Score=801, Pubmed Id: 11675357, UMLKSK CUI: C0085669
img NCI, Score=801, Pubmed Id: 11675357, UMLKSK CUI: C0085669
HumanCHFR55743checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
img NCI, Score=801, Pubmed Id: 16029562, UMLKSK CUI: C0085669
img NCI, Score=801, Pubmed Id: 16029562, UMLKSK CUI: C0085669
img NCI, Score=801, Pubmed Id: 16029562, UMLKSK CUI: C0085669
HumanFBXW755294F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
img GENERIF, Score=694, Pubmed Id: 17992009, UMLKSK CUI: C0085669
HumanANKHD154882ankyrin repeat and KH domain containing 1
img NCI, Score=801, Pubmed Id: 16956752, UMLKSK CUI: C0085669
img NCI, Score=801, Pubmed Id: 16956752, UMLKSK CUI: C0085669
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0085669Acute leukemia0self