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Details
Link-It Detail - Disease - ERYTHEMA MARGINATUM
Debug Stats
  • ### Total Build Time: 6 ms 5.970 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 336 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 1.428 KB
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=2 ms Completed: 2 ms rowSize= 1.623 KB
  • CONCEPT_GENES gt=1 ms Completed: 1 ms rowSize= 1.367 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.153 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
ERYTHEMA MARGINATUM C0085659
Definition (1)
WHAT: Erythema marginatum. Erythema Marginatum: an evanescent, erythematous rash characteris- tically (though not commonly) seen in the early stages of rheumatic fever. The rash is not limited to rheumatic fever, however, and has also been reported in patients with allergic drug reactions, sepsis and glomerulonephritis. WHY: Although the rash is not pathognomonic of rheumatic fever, its presence is helpful in conjunction with other manifestations of rheumatic fever, particularly carditis with which it is most often associated. HOW: The rash is characterized by pink, evanescent, slightly raised small macules with a sharply demarcated and irregular border. The erythematous areas often have pale centers. The rash commonly occurs over the trunk and inner aspects of the upper arms and thighs, but never on the face. It is non-painful and rarely pruritic, may appear and disappear in a matter of hours only to return, and may be brought out by a hot bath or shower. The rash blanches on pressure, and is a transient rash which tends to migrate from place to place. REFS: 1) Jones criteria (revised) for guidance in the diagnosis of rheumatic fever. Circulation 32:664, 1965. 2) Dictionary of the Rheumatic Diseases, Volume I: Signs and Symptoms. American Rheumatism Association, 1982. (Descriptor #133).
Relationships (2)

Relation Types:
diso_​to_​diso : 2


Relationships:
none : 1
isa : 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISOisaimg Erythema marginatum in acute rheumatic fever C0451910
DISO_to_DISOimg Rheumatic Fever C0035436
Genes (1)

Species:
human : 1
SpeciesGeneGeneIdGene NameEvidence
HumanSERPING1710serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
img OMIM, Score=1000, UMLKSK CUI: C0085659
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0085659ERYTHEMA MARGINATUM0self