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Details
Link-It Detail - Disease - POEMS Syndrome
Debug Stats
  • ### Total Build Time: 46 ms 18.983 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 376 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 697 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=26 ms Completed: 26 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 1.395 KB
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=3 ms Completed: 3 ms rowSize= 5.390 KB
  • CONCEPT_RELATIONSHIPS gt=7 ms Completed: 7 ms rowSize= 7.499 KB
  • CONCEPT_GENES gt=2 ms Completed: 2 ms rowSize= 2.285 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.148 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
POEMS Syndrome C0085404
Crow Fukase Syndrome
Definition (1)
A multisystemic disorder characterized by a sensorimotor polyneuropathy (POLYNEUROPATHIES), organomegaly, endocrinopathy, monoclonal gammopathy, and pigmentary skin changes. Other clinical features which may be present include EDEMA; CACHEXIA; microangiopathic glomerulopathy; pulmonary hypertension (HYPERTENSION, PULMONARY); cutaneous necrosis; THROMBOCYTOSIS; and POLYCYTHEMIA. This disorder is frequently associated with osteosclerotic myeloma. (From Adams et al., Principles of Neurology, 6th ed, p1335; Rev Med Interne 1997;18(7):553-62)
Semantic Types (1)
Disease or Syndrome (T047)
Parents (3)
img Polyneuropathies C0152025
img Paraproteinemias C0030489
img Abnormalities, Multiple C0000772
Ancestral Roots
RootRoot Plus OneDepthParent
img Nervous System Diseases C0027765img Neuromuscular Diseases C00278685img Polyneuropathies C0152025
img Immune System Diseases C0021053img Immunoproliferative Disorders C00210704img Paraproteinemias C0030489
img Hemic and Lymphatic Diseases C0018981img Hematologic Diseases C00189395img Paraproteinemias C0030489
img Congenital, Hereditary, and Neonatal Diseases and Abnormalities C0027612img Congenital Abnormalities C00007684img Abnormalities, Multiple C0000772
Relationships (18)

Relation Types:
diso_​to_​anat : 2
diso_​to_​chem : 5
diso_​to_​diso : 11


Relationships:
none : 17
permuted_​term_​of : 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO69img Complication Aspects C1171258
DISO_to_DISO40img Complication Aspects C1171258
DISO_to_ANAT25img In Blood C0005768
DISO_to_CHEM22img Vascular Endothelial Growth Factor A C0078058
DISO_to_ANAT17img In Blood C0005768
DISO_to_CHEM15img (+)-Thalidomide C0039736
DISO_to_DISO13img Angiolymphoid hyperplasia C0017531
DISO_to_DISO11img Cutaneous tumor C0037286
DISO_to_DISO11img Hemangioma C0018916
DISO_to_DISO9img Hemangioma C0018916
DISO_to_DISO8img Cutaneous tumor C0037286
DISO_to_DISO7img Multiple Myeloma C0026764
DISO_to_CHEM6img ANGIOGENESIS INHIB C0596087
DISO_to_CHEM6img Acids, Boronic C0006032
DISO_to_CHEM6img Pyrazines C0034240
DISO_to_DISO6img Plasmacytoma C0032131
DISO_to_DISO6img Polyradiculoneuropathy, Chronic Inflammatory Demyelinating C0393819
DISO_to_DISOpermuted_term_ofimg Crow Fukase Syndrome C0085404
Genes (1)

Species:
human : 1
SpeciesGeneGeneIdGene NameEvidence
HumanVEGFA7422vascular endothelial growth factor A
img GENERIF, Score=1000, Pubmed Id: 17277913, UMLKSK CUI: C0085404
img GENERIF, Score=827, Pubmed Id: 17895817, UMLKSK CUI: C0085404
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0085404POEMS Syndrome0self