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Details
Link-It Detail - Disease - Lymphoma, Large B-Cell, Diffuse
Debug Stats
  • ### Total Build Time: 568 ms 64.100 KB
  • CONCEPT_NAME gt=18 ms Completed: 18 ms rowSize= 419 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 543 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=12 ms Completed: 12 ms rowSize= 552 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=8 ms Completed: 8 ms rowSize= 4.058 KB
  • CONCEPT_RELATIONSHIPS gt=432 ms Completed: 432 ms rowSize= 16.308 KB
  • CONCEPT_GENES gt=84 ms Completed: 84 ms rowSize= 40.873 KB
  • CONCEPT_XREFS gt=13 ms Completed: 13 ms rowSize= 1.165 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
Lymphoma, Large B-Cell, Diffuse C0079744
Diffuse Large B-Cell Lymphoma
Definition (1)
A type of B-cell non-Hodgkin lymphoma (cancer of the immune system) that is usually aggressive (fast-growing). It is the most common type of non-Hodgkin lymphoma, and is marked by rapidly growing tumors in the lymph nodes, spleen, liver, bone marrow, or other organs. Other symptoms include fever, night sweats, and weight loss. There are several subtypes of diffuse large B-cell lymphoma.
Semantic Types (1)
Neoplastic Process (T191)
Parents (1)
img Lymphoma, B-Cell C0079731
Ancestral Roots
RootRoot Plus OneDepthParent
img Immune System Diseases C0021053img Immunoproliferative Disorders C00210707img Lymphoma, B-Cell C0079731
img Hemic and Lymphatic Diseases C0018981img Lymphatic Diseases C00242287img Lymphoma, B-Cell C0079731
img Neoplasms C0027651img Neoplasms by Histologic Type C00276526img Lymphoma, B-Cell C0079731
Relationships (200)

Relation Types:
diso_​to_​anat : 30
diso_​to_​chem : 37
diso_​to_​diso : 115
diso_​to_​gene : 8
diso_​to_​phen : 2
diso_​to_​phys : 8


Relationships:
none : 125
eo_​disease_​maps_​to_​human_​disease : 8
gene_​associated_​with_​disease : 6
gene_​product_​malfunction_​associated_​with_​disease : 1
is_​abnormal_​cell_​of_​disease : 6
is_​finding_​of_​disease : 1
is_​normal_​cell_​origin_​of_​disease : 4
is_​normal_​tissue_​origin_​of_​disease : 2
is_​not_​abnormal_​cell_​of_​disease : 2
is_​not_​normal_​cell_​origin_​of_​disease : 3
is_​primary_​anatomic_​site_​of_​disease : 2
isa : 37
may_​be_​molecular_​abnormality_​of_​disease : 2
permuted_​term_​of : 1
Page Size
Current 25
  Page 1 of 8
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO773img Lymphoma, B-Cell C0079731
DISO_to_PHEN517img genetic aspects C0017399
DISO_to_PHEN350img genetic aspects C0017399
DISO_to_DISO334img Complication Aspects C1171258
DISO_to_DISO243img B-Cell Lymphomas C0079731
DISO_to_DISO174img Complication Aspects C1171258
DISO_to_CHEM173img Antibodies, Monoclonal C0003250
DISO_to_CHEM135img Antineoplastic Agents C0003392
DISO_to_CHEM104img Tumor Markers, Biological C0041366
DISO_to_DISO102img Cutaneous tumor C0037286
DISO_to_DISO102img Lymphoma, Follicular C0024301
DISO_to_DISO92img Vascular Neoplasms C0282607
DISO_to_CHEM82img Antibodies, Monoclonal, Murine-Derived C2916903
DISO_to_CHEM78img Antibodies, Monoclonal C0003250
DISO_to_ANAT72img In Blood C0005768
DISO_to_CHEM67img Protein Tyrosine Kinase C0033681
DISO_to_DISO65img Stomach Neoplasms C0038356
DISO_to_CHEM62img BIOCHEM TUMOR MARKERS C0041366
DISO_to_DISO62img Central Nervous System Neoplasms C0085136
DISO_to_DISO59img EBV INFECT C0149678
DISO_to_DISO59img Hodgkin Disease C0019829
DISO_to_DISO59img Mediastinal Neoplasms C0025063
DISO_to_PHYS58img Gene Expression Regulation, Neoplastic C0017268
DISO_to_ANAT57img B-Lymphocytes C0004561
DISO_to_DISO57img Brain Neoplasms C0006118
Genes (157)

Species:
human : 157
Page Size
Current 25
  Page 1 of 7
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanMIR17HG407975miR-17-92 cluster host gene (non-protein coding)
img NCI, Score=801, Pubmed Id: 15126345, UMLKSK CUI: C0079744
HumanSERPINA9327657serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9
img NCI, Score=801, Pubmed Id: 12819018, UMLKSK CUI: C0079744
img GENERIF, Score=1000, Pubmed Id: 12819018, UMLKSK CUI: C0079744
HumanGCET2257144
Click here to display 5 evidence detail records.
HumanPASD1139135PAS domain containing 1
img NCI, Score=801, Pubmed Id: 15162151, UMLKSK CUI: C0079744
img NCI, Score=801, Pubmed Id: 15162151, UMLKSK CUI: C0079744
HumanTNFRSF13C115650tumor necrosis factor receptor superfamily, member 13C
img NCI, Score=801, Pubmed Id: 16025281, UMLKSK CUI: C0079744
img NCI, Score=801, Pubmed Id: 16025281, UMLKSK CUI: C0079744
HumanMIR155HG114614MIR155 host gene (non-protein coding)
img NCI, Score=801, Pubmed Id: 16041695, UMLKSK CUI: C0079744
img NCI, Score=801, Pubmed Id: 16041695, UMLKSK CUI: C0079744
img NCI, Score=801, Pubmed Id: 16041695, UMLKSK CUI: C0079744
HumanMUM184939melanoma associated antigen (mutated) 1
img NCI, Score=801, Pubmed Id: 16918993, UMLKSK CUI: C0079744
img NCI, Score=801, Pubmed Id: 17327602, UMLKSK CUI: C0079744
img NCI, Score=801, Pubmed Id: 16918993, UMLKSK CUI: C0079744
img NCI, Score=801, Pubmed Id: 17335572, UMLKSK CUI: C0079744
HumanFCRLA84824Fc receptor-like A
img NCI, Score=801, Pubmed Id: 15491296, UMLKSK CUI: C0079744
img NCI, Score=801, Pubmed Id: 11891275, UMLKSK CUI: C0079744
HumanCARD1184433caspase recruitment domain family, member 11
Click here to display 5 evidence detail records.
HumanC7orf6379846chromosome 7 open reading frame 63
img GENERIF, Score=1000, Pubmed Id: 18288132, UMLKSK CUI: C0079744
HumanBACH260468BTB and CNC homology 1, basic leucine zipper transcription factor 2
img NCI, Score=801, Pubmed Id: 16258099, UMLKSK CUI: C0079744
img NCI, Score=801, Pubmed Id: 16258099, UMLKSK CUI: C0079744
img NCI, Score=801, Pubmed Id: 16258099, UMLKSK CUI: C0079744
img NCI, Score=801, Pubmed Id: 16258099, UMLKSK CUI: C0079744
HumanIL2159067interleukin 21
img NCI, Score=801, Pubmed Id: 11821949, UMLKSK CUI: C0079744
HumanRIPK454101receptor-interacting serine-threonine kinase 4
img GENERIF, Score=947, Pubmed Id: 18025152, UMLKSK CUI: C0079744
HumanBCL11A53335B-cell CLL/lymphoma 11A (zinc finger protein)
img NCI, Score=801, Pubmed Id: 12406872, UMLKSK CUI: C0079744
HumanGMNN51053geminin, DNA replication inhibitor
img NCI, Score=801, Pubmed Id: 15682442, UMLKSK CUI: C0079744
img NCI, Score=801, Pubmed Id: 15682442, UMLKSK CUI: C0079744
HumanIL21R50615interleukin 21 receptor
img NCI, Score=801, Pubmed Id: 11821949, UMLKSK CUI: C0079744
HumanMCTS128985malignant T cell amplified sequence 1
img NCI, Score=801, Pubmed Id: 12637315, UMLKSK CUI: C0079744
HumanFOXP127086forkhead box P1
Click here to display 16 evidence detail records.
HumanCKAP226586cytoskeleton associated protein 2
img NCI, Score=801, Pubmed Id: 11234418, UMLKSK CUI: C0079744
img NCI, Score=801, Pubmed Id: 11234418, UMLKSK CUI: C0079744
HumanSIRT123411sirtuin 1
img GENERIF, Score=1000, Pubmed Id: 18724249, UMLKSK CUI: C0079744
HumanSWAP7023075SWAP switching B-cell complex 70kDa subunit
img NCI, Score=801, Pubmed Id: 15163014, UMLKSK CUI: C0079744
HumanMETAP210988methionyl aminopeptidase 2
img NCI, Score=801, Pubmed Id: 12118091, UMLKSK CUI: C0079744
HumanMALT110892mucosa associated lymphoid tissue lymphoma translocation gene 1
Click here to display 5 evidence detail records.
HumanTNFSF13B10673tumor necrosis factor (ligand) superfamily, member 13b
img NCI, Score=801, Pubmed Id: 15251985, UMLKSK CUI: C0079744
HumanTXNIP10628thioredoxin interacting protein
img NCI, Score=801, Pubmed Id: 16081686, UMLKSK CUI: C0079744
img NCI, Score=801, Pubmed Id: 12594241, UMLKSK CUI: C0079744
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0079744Lymphoma, Large B-Cell, Diffuse0self