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Details
Link-It Detail - Disease - Lymphoma, Large B-Cell, Diffuse
Debug Stats
  • ### Total Build Time: 424 ms 64.023 KB
  • CONCEPT_NAME gt=11 ms Completed: 11 ms rowSize= 419 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 477 bytes
  • CONCEPT_SYNONYM gt=NONE 1 ms Completed: 1 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=13 ms Completed: 13 ms rowSize= 552 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=5 ms Completed: 5 ms rowSize= 4.058 KB
  • CONCEPT_RELATIONSHIPS gt=293 ms Completed: 293 ms rowSize= 16.304 KB
  • CONCEPT_GENES gt=88 ms Completed: 88 ms rowSize= 40.865 KB
  • CONCEPT_XREFS gt=11 ms Completed: 11 ms rowSize= 1.165 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
Lymphoma, Large B-Cell, Diffuse C0079744
Diffuse Large B-Cell Lymphoma
Definition (1)
Malignant lymphoma composed of large B lymphoid cells whose nuclear size can exceed normal macrophage nuclei, or more than twice the size of a normal lymphocyte. The pattern is predominantly diffuse. Most of these lymphomas represent the malignant counterpart of B-lymphocytes at midstage in the process of differentiation.
Semantic Types (1)
Neoplastic Process (T191)
Parents (1)
img Lymphoma, B-Cell C0079731
Ancestral Roots
RootRoot Plus OneDepthParent
img Immune System Diseases C0021053img Immunoproliferative Disorders C00210707img Lymphoma, B-Cell C0079731
img Hemic and Lymphatic Diseases C0018981img Lymphatic Diseases C00242287img Lymphoma, B-Cell C0079731
img Neoplasms C0027651img Neoplasms by Histologic Type C00276526img Lymphoma, B-Cell C0079731
Relationships (200)

Relation Types:
diso_​to_​anat : 30
diso_​to_​chem : 37
diso_​to_​diso : 115
diso_​to_​gene : 8
diso_​to_​phen : 2
diso_​to_​phys : 8


Relationships:
none : 125
eo_​disease_​maps_​to_​human_​disease : 8
gene_​associated_​with_​disease : 6
gene_​product_​malfunction_​associated_​with_​disease : 1
is_​abnormal_​cell_​of_​disease : 6
is_​finding_​of_​disease : 1
is_​normal_​cell_​origin_​of_​disease : 4
is_​normal_​tissue_​origin_​of_​disease : 2
is_​not_​abnormal_​cell_​of_​disease : 2
is_​not_​normal_​cell_​origin_​of_​disease : 3
is_​primary_​anatomic_​site_​of_​disease : 2
isa : 37
may_​be_​molecular_​abnormality_​of_​disease : 2
permuted_​term_​of : 1
Page Size
Current 25
  Page 1 of 8
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO773img Lymphoma, B-Cell C0079731
DISO_to_PHEN517img genetic aspects C0017399
DISO_to_PHEN350img genetic aspects C0017399
DISO_to_DISO334img Complication Aspects C1171258
DISO_to_DISO243img B-Cell Lymphomas C0079731
DISO_to_DISO174img Complication Aspects C1171258
DISO_to_CHEM173img Antibodies, Monoclonal C0003250
DISO_to_CHEM135img Antineoplastic Agents C0003392
DISO_to_CHEM104img BIOCHEM TUMOR MARKERS C0041366
DISO_to_DISO102img Cutaneous tumor C0037286
DISO_to_DISO102img Lymphoma, Follicular C0024301
DISO_to_DISO92img Vascular Neoplasms C0282607
DISO_to_CHEM82img Antibodies, Monoclonal, Murine-Derived C2916903
DISO_to_CHEM78img Antibodies, Monoclonal C0003250
DISO_to_ANAT72img In Blood C0005768
DISO_to_CHEM67img Protein Tyrosine Kinase C0033681
DISO_to_DISO65img Stomach Neoplasms C0038356
DISO_to_CHEM62img BIOCHEM TUMOR MARKERS C0041366
DISO_to_DISO62img Central Nervous System Neoplasms C0085136
DISO_to_DISO59img EBV INFECT C0149678
DISO_to_DISO59img Hodgkin Disease C0019829
DISO_to_DISO59img Mediastinal Neoplasms C0025063
DISO_to_PHYS58img Gene Expression Regulation, Neoplastic C0017268
DISO_to_ANAT57img B-Lymphocytes C0004561
DISO_to_DISO57img Brain Neoplasms C0006118
Genes (157)

Species:
human : 157
Page Size
Current 25
  Page 1 of 7
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanMIR17HG407975miR-17-92 cluster host gene (non-protein coding)
img NCI, Score=801, Pubmed Id: 15126345, UMLKSK CUI: C0079744
HumanSERPINA9327657serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9
img GENERIF, Score=1000, Pubmed Id: 12819018, UMLKSK CUI: C0079744
img NCI, Score=801, Pubmed Id: 12819018, UMLKSK CUI: C0079744
HumanGCET2257144
Click here to display 5 evidence detail records.
HumanPASD1139135PAS domain containing 1
img NCI, Score=801, Pubmed Id: 15162151, UMLKSK CUI: C0079744
img NCI, Score=801, Pubmed Id: 15162151, UMLKSK CUI: C0079744
HumanTNFRSF13C115650tumor necrosis factor receptor superfamily, member 13C
img NCI, Score=801, Pubmed Id: 16025281, UMLKSK CUI: C0079744
img NCI, Score=801, Pubmed Id: 16025281, UMLKSK CUI: C0079744
HumanMIR155HG114614MIR155 host gene (non-protein coding)
img NCI, Score=801, Pubmed Id: 16041695, UMLKSK CUI: C0079744
img NCI, Score=801, Pubmed Id: 16041695, UMLKSK CUI: C0079744
img NCI, Score=801, Pubmed Id: 16041695, UMLKSK CUI: C0079744
HumanMUM184939melanoma associated antigen (mutated) 1
img NCI, Score=801, Pubmed Id: 16918993, UMLKSK CUI: C0079744
img NCI, Score=801, Pubmed Id: 17327602, UMLKSK CUI: C0079744
img NCI, Score=801, Pubmed Id: 17335572, UMLKSK CUI: C0079744
img NCI, Score=801, Pubmed Id: 16918993, UMLKSK CUI: C0079744
HumanFCRLA84824Fc receptor-like A
img NCI, Score=801, Pubmed Id: 15491296, UMLKSK CUI: C0079744
img NCI, Score=801, Pubmed Id: 11891275, UMLKSK CUI: C0079744
HumanCARD1184433caspase recruitment domain family, member 11
Click here to display 5 evidence detail records.
HumanC7orf6379846chromosome 7 open reading frame 63
img GENERIF, Score=1000, Pubmed Id: 18288132, UMLKSK CUI: C0079744
HumanBACH260468BTB and CNC homology 1, basic leucine zipper transcription factor 2
img NCI, Score=801, Pubmed Id: 16258099, UMLKSK CUI: C0079744
img NCI, Score=801, Pubmed Id: 16258099, UMLKSK CUI: C0079744
img NCI, Score=801, Pubmed Id: 16258099, UMLKSK CUI: C0079744
img NCI, Score=801, Pubmed Id: 16258099, UMLKSK CUI: C0079744
HumanIL2159067interleukin 21
img NCI, Score=801, Pubmed Id: 11821949, UMLKSK CUI: C0079744
HumanRIPK454101receptor-interacting serine-threonine kinase 4
img GENERIF, Score=947, Pubmed Id: 18025152, UMLKSK CUI: C0079744
HumanBCL11A53335B-cell CLL/lymphoma 11A (zinc finger protein)
img NCI, Score=801, Pubmed Id: 12406872, UMLKSK CUI: C0079744
HumanGMNN51053geminin, DNA replication inhibitor
img NCI, Score=801, Pubmed Id: 15682442, UMLKSK CUI: C0079744
img NCI, Score=801, Pubmed Id: 15682442, UMLKSK CUI: C0079744
HumanIL21R50615interleukin 21 receptor
img NCI, Score=801, Pubmed Id: 11821949, UMLKSK CUI: C0079744
HumanMCTS128985malignant T cell amplified sequence 1
img NCI, Score=801, Pubmed Id: 12637315, UMLKSK CUI: C0079744
HumanFOXP127086forkhead box P1
Click here to display 16 evidence detail records.
HumanCKAP226586cytoskeleton associated protein 2
img NCI, Score=801, Pubmed Id: 11234418, UMLKSK CUI: C0079744
img NCI, Score=801, Pubmed Id: 11234418, UMLKSK CUI: C0079744
HumanSIRT123411sirtuin 1
img GENERIF, Score=1000, Pubmed Id: 18724249, UMLKSK CUI: C0079744
HumanSWAP7023075SWAP switching B-cell complex 70kDa subunit
img NCI, Score=801, Pubmed Id: 15163014, UMLKSK CUI: C0079744
HumanMETAP210988methionyl aminopeptidase 2
img NCI, Score=801, Pubmed Id: 12118091, UMLKSK CUI: C0079744
HumanMALT110892mucosa associated lymphoid tissue lymphoma translocation gene 1
Click here to display 5 evidence detail records.
HumanTNFSF13B10673tumor necrosis factor (ligand) superfamily, member 13b
img NCI, Score=801, Pubmed Id: 15251985, UMLKSK CUI: C0079744
HumanTXNIP10628thioredoxin interacting protein
img NCI, Score=801, Pubmed Id: 16081686, UMLKSK CUI: C0079744
img NCI, Score=801, Pubmed Id: 12594241, UMLKSK CUI: C0079744
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0079744Lymphoma, Large B-Cell, Diffuse0self