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Details
Link-It Detail - Disease - Rhabdomyosarcoma
Debug Stats
  • ### Total Build Time: 116 ms 63.361 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 330 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 842 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 546 bytes
  • CONCEPT_CHILDREN gt=3 ms Completed: 3 ms rowSize= 1,009 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=5 ms Completed: 5 ms rowSize= 1.495 KB
  • CONCEPT_RELATIONSHIPS gt=69 ms Completed: 69 ms rowSize= 16.517 KB
  • CONCEPT_GENES gt=29 ms Completed: 29 ms rowSize= 41.326 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.150 KB
  • CONCEPT_ANCILLARY gt=2 ms Completed: 2 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Rhabdomyosarcoma C0035412
Definition (1)
A malignant solid tumor arising from mesenchymal tissues which normally differentiate to form striated muscle. It can occur in a wide variety of sites. It is divided into four distinct types: pleomorphic, predominantly in male adults; alveolar (RHABDOMYOSARCOMA, ALVEOLAR), mainly in adolescents and young adults; embryonal (RHABDOMYOSARCOMA, EMBRYONAL), predominantly in infants and children; and botryoidal, also in young children. It is one of the most frequently occurring soft tissue sarcomas and the most common in children under 15. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p2186; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, pp1647-9)
Semantic Types (1)
Neoplastic Process (T191)
Parents (1)
img Myosarcoma C0027095
Children (2)
img Rhabdomyosarcoma, Alveolar C0206655
img Rhabdomyosarcoma, Embryonal C0206656
Ancestral Roots
RootRoot Plus OneDepthParent
img Neoplasms C0027651img Neoplasms by Histologic Type C00276526img Myosarcoma C0027095
Relationships (166)

Relation Types:
diso_​to_​anat : 17
diso_​to_​chem : 35
diso_​to_​diso : 88
diso_​to_​gene : 15
diso_​to_​phen : 2
diso_​to_​phys : 9


Relationships:
none : 75
eo_​disease_​maps_​to_​human_​disease : 5
gene_​associated_​with_​disease : 14
gene_​product_​malfunction_​associated_​with_​disease : 6
is_​abnormal_​cell_​of_​disease : 7
is_​associated_​anatomic_​site_​of : 1
is_​finding_​of_​disease : 2
is_​normal_​cell_​origin_​of_​disease : 3
is_​normal_​tissue_​origin_​of_​disease : 2
is_​not_​finding_​of_​disease : 3
is_​not_​normal_​cell_​origin_​of_​disease : 2
is_​not_​normal_​tissue_​origin_​of_​disease : 1
isa : 24
mapped_​to : 1
may_​treat : 19
used_​for : 1
Page Size
Current 25
  Page 1 of 7
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_PHEN103img genetic aspects C0017399
DISO_to_PHEN90img genetic aspects C0017399
DISO_to_DISO53img Soft Tissue Neoplasms C0037579
DISO_to_DISO40img Complication Aspects C1171258
DISO_to_DISO40img Soft Tissue Neoplasms C0037579
DISO_to_DISO25img Bladder Neoplasm C0005695
DISO_to_DISO25img Head and Neck Neoplasms C0018671
DISO_to_DISO24img Complication Aspects C1171258
DISO_to_DISO23img Neoplasm of Orbit C0029185
DISO_to_DISO22img Ewings sarcoma C0553580
DISO_to_DISO22img Head and Neck Neoplasms C0018671
DISO_to_DISO21img Testicular Neoplasms C0039590
DISO_to_DISO20img Heart Neoplasm C0018809
DISO_to_DISO20img Prostatic Neoplasms C0033578
DISO_to_DISO19img Neuroblastoma C0027819
DISO_to_DISO19img Testicular Neoplasms C0039590
DISO_to_DISO18img Bladder Neoplasm C0005695
DISO_to_DISO18img Neoplasm of Orbit C0029185
DISO_to_DISO17img Lung Neoplasms C0024121
DISO_to_DISO17img Osteosarcoma C0029463
DISO_to_DISO16img Ewings sarcoma C0553580
DISO_to_DISO16img Prostatic Neoplasms C0033578
DISO_to_DISO15img Bone Neoplasms C0005967
DISO_to_DISO14img Heart Neoplasm C0018809
DISO_to_DISO14img Sarcoma C1261473
Genes (137)

Species:
human : 130
mouse : 7
Page Size
Current 25
  Page 1 of 6
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
MouseEZR7430ezrin
img NCI, Score=801, Pubmed Id: 14704789, UMLKSK CUI: C0035412
MousePAX35077paired box 3
img NCI, Score=801, Pubmed Id: 8917562, UMLKSK CUI: C0035412
img NCI, Score=801, Pubmed Id: 11863357, UMLKSK CUI: C0035412
img NCI, Score=801, Pubmed Id: 16938866, UMLKSK CUI: C0035412
MouseLDHA3939lactate dehydrogenase A
img NCI, Score=801, Pubmed Id: 7256865, UMLKSK CUI: C0035412
MouseITGA23673integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
img NCI, Score=801, Pubmed Id: 8674074, UMLKSK CUI: C0035412
MouseIL153600interleukin 15
img NCI, Score=801, Pubmed Id: 9259773, UMLKSK CUI: C0035412
img NCI, Score=801, Pubmed Id: 9862733, UMLKSK CUI: C0035412
MouseIGFBP63489insulin-like growth factor binding protein 6
img NCI, Score=801, Pubmed Id: 11745458, UMLKSK CUI: C0035412
img NCI, Score=801, Pubmed Id: 11745458, UMLKSK CUI: C0035412
img NCI, Score=801, Pubmed Id: 14710364, UMLKSK CUI: C0035412
img NCI, Score=801, Pubmed Id: 11745458, UMLKSK CUI: C0035412
MouseFOXO12308forkhead box O1
img NCI, Score=801, Pubmed Id: 12606579, UMLKSK CUI: C0035412
HumanMIR29A407021microRNA 29a
img GENERIF, Score=1000, Pubmed Id: 18977326, UMLKSK CUI: C0035412
HumanRMST196475rhabdomyosarcoma 2 associated transcript (non-protein coding)
img NCI, Score=801, Pubmed Id: 12082533, UMLKSK CUI: C0035412
HumanJDP2122953Jun dimerization protein 2
img NCI, Score=801, Pubmed Id: 12171923, UMLKSK CUI: C0035412
img NCI, Score=801, Pubmed Id: 12171923, UMLKSK CUI: C0035412
HumanSCGB3A192304secretoglobin, family 3A, member 1
img NCI, Score=801, Pubmed Id: 15472908, UMLKSK CUI: C0035412
HumanBOC91653BOC cell adhesion associated, oncogene regulated
img NCI, Score=801, Pubmed Id: 12720294, UMLKSK CUI: C0035412
img NCI, Score=801, Pubmed Id: 12720294, UMLKSK CUI: C0035412
HumanANTXR184168anthrax toxin receptor 1
img NCI, Score=801, Pubmed Id: 10534762, UMLKSK CUI: C0035412
HumanFEM1A55527fem-1 homolog a (C. elegans)
img GENERIF, Score=694, Pubmed Id: 16254458, UMLKSK CUI: C0035412
HumanCDON50937cell adhesion associated, oncogene regulated
img NCI, Score=801, Pubmed Id: 12720294, UMLKSK CUI: C0035412
img NCI, Score=801, Pubmed Id: 12720294, UMLKSK CUI: C0035412
HumanTRPM529850transient receptor potential cation channel, subfamily M, member 5
img NCI, Score=801, Pubmed Id: 10607831, UMLKSK CUI: C0035412
HumanANKRD226287ankyrin repeat domain 2 (stretch responsive muscle)
img GENERIF, Score=1000, Pubmed Id: 16021567, UMLKSK CUI: C0035412
HumanICOSLG23308inducible T-cell co-stimulator ligand
img NCI, Score=801, Pubmed Id: 12690043, UMLKSK CUI: C0035412
HumanCOPS510987COP9 signalosome subunit 5
img NCI, Score=801, Pubmed Id: 12359053, UMLKSK CUI: C0035412
HumanNES10763nestin
img NCI, Score=801, Pubmed Id: 9505279, UMLKSK CUI: C0035412
HumanCHL110752cell adhesion molecule L1-like
img NCI, Score=801, Pubmed Id: 2189373, UMLKSK CUI: C0035412
HumanTNFSF13B10673tumor necrosis factor (ligand) superfamily, member 13b
img GENERIF, Score=660, Pubmed Id: 18625509, UMLKSK CUI: C0035412
HumanMVP9961major vault protein
img NCI, Score=801, Pubmed Id: 12612883, UMLKSK CUI: C0035412
img NCI, Score=801, Pubmed Id: 12612883, UMLKSK CUI: C0035412
img NCI, Score=801, Pubmed Id: 12612883, UMLKSK CUI: C0035412
HumanXAGE1D9503X antigen family, member 1D
img NCI, Score=801, Pubmed Id: 10197611, UMLKSK CUI: C0035412
img NCI, Score=801, Pubmed Id: 12479262, UMLKSK CUI: C0035412
HumanXAGE29502X antigen family, member 2
img NCI, Score=801, Pubmed Id: 10197611, UMLKSK CUI: C0035412
img NCI, Score=801, Pubmed Id: 10197611, UMLKSK CUI: C0035412
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0035412Rhabdomyosarcoma0self