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Details
Link-It Detail - Disease - Restless Legs Syndrome
Debug Stats
  • ### Total Build Time: 34 ms 43.509 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 342 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 480 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 991 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=6 ms Completed: 6 ms rowSize= 10.448 KB
  • CONCEPT_RELATIONSHIPS gt=13 ms Completed: 13 ms rowSize= 12.924 KB
  • CONCEPT_GENES gt=8 ms Completed: 8 ms rowSize= 16.991 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.156 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Restless Legs Syndrome C0035258
Definition (1)
A condition in which a person has a strong urge to move his or her legs in order to stop uncomfortable sensations. These include burning, itching, creeping, tugging, crawling, or pain. These feelings usually happen when a person is lying or sitting down, and are worse at night. They can also occur in other parts of the body.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (2)
img Sleep Disorders, Intrinsic C0752287
img Parasomnias C0030508
Ancestral Roots
RootRoot Plus OneDepthParent
img Pathological Conditions, Signs and Symptoms C0039058img Signs and Symptoms C00370887img Sleep Disorders, Intrinsic C0752287
img Nervous System Diseases C0027765img Neurologic Manifestations C00278546img Sleep Disorders, Intrinsic C0752287
img Mental Disorders C0004936img Sleep Disorders C08515785img Sleep Disorders, Intrinsic C0752287
img Nervous System Diseases C0027765img Sleep Disorders C08515785img Sleep Disorders, Intrinsic C0752287
img Pathological Conditions, Signs and Symptoms C0039058img Signs and Symptoms C00370886img Parasomnias C0030508
img Nervous System Diseases C0027765img Neurologic Manifestations C00278545img Parasomnias C0030508
img Mental Disorders C0004936img Sleep Disorders C08515784img Parasomnias C0030508
img Nervous System Diseases C0027765img Sleep Disorders C08515784img Parasomnias C0030508
Relationships (73)

Relation Types:
diso_​to_​anat : 4
diso_​to_​chem : 42
diso_​to_​diso : 21
diso_​to_​phen : 2
diso_​to_​phys : 4


Relationships:
none : 43
mapped_​to : 3
may_​treat : 24
related_​to : 3
Page Size
Current 25
  Page 1 of 3
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO144img Complication Aspects C1171258
DISO_to_CHEM107img Dopamine Agonists C0178601
DISO_to_PHEN75img genetic aspects C0017399
DISO_to_CHEM72img Dopamine Agonists C0178601
DISO_to_DISO61img Complication Aspects C1171258
DISO_to_DISO45img EXCESSIVE PERIODIC SLEEP RELAT LEG MOVEMENTS C0751774
DISO_to_PHEN45img genetic aspects C0017399
DISO_to_CHEM44img Benzothiazoles C1567965
DISO_to_DISO44img chemically induced C0007994
DISO_to_DISO39img EXCESSIVE PERIODIC SLEEP RELAT LEG MOVEMENTS C0751774
DISO_to_ANAT36img In Blood C0005768
DISO_to_DISO35img Parkinson Disease C0030567
DISO_to_CHEM29img Indoles C0021242
DISO_to_CHEM25img Indoles C0021242
DISO_to_DISO24img chemically induced C0007994
DISO_to_CHEM22img (-)-3-(3,4-Dihydroxyphenyl)-L-alanine C0023570
DISO_to_PHYS22img Sleep C0037313
DISO_to_DISO21img Sleep Disorders C0851578
DISO_to_CHEM20img Iron C0302583
DISO_to_CHEM20img Tetrahydronaphthalenes C0039673
DISO_to_CHEM20img Thiophenes C0039931
DISO_to_DISO20img Parkinson Disease C0030567
DISO_to_CHEM19img .GAMMA.-AMINOBUTYRIC ACID C0016904
DISO_to_DISO19img Attention Deficit Disorder with Hyperactivity C1263846
DISO_to_DISO18img DIMS (Disorders of Initiating and Maintaining Sleep) C0021603
Genes (15)

Species:
human : 15
SpeciesGeneGeneIdGene NameEvidence
HumanSKOR1390598SKI family transcriptional corepressor 1
img GENERIF, Score=1000, Pubmed Id: 18541116, UMLKSK CUI: C0035258
HumanBTBD9114781BTB (POZ) domain containing 9
img GENERIF, Score=923, Pubmed Id: 18363860, UMLKSK CUI: C0035258
HumanTBP6908TATA box binding protein
img GAD, Score=1000, Pubmed Id: 16389595, UMLKSK CUI: C0035258
HumanATXN76314ataxin 7
img GAD, Score=1000, Pubmed Id: 16389595, UMLKSK CUI: C0035258
HumanATXN26311ataxin 2
img GAD, Score=1000, Pubmed Id: 16389595, UMLKSK CUI: C0035258
HumanATXN16310ataxin 1
img GAD, Score=1000, Pubmed Id: 16389595, UMLKSK CUI: C0035258
HumanPTPRD5789protein tyrosine phosphatase, receptor type, D
img GENERIF, Score=1000, Pubmed Id: 18660810, UMLKSK CUI: C0035258
HumanNTS4922neurotensin
img GENERIF, Score=694, Pubmed Id: 17644423, UMLKSK CUI: C0035258
HumanSLC11A24891solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
img GENERIF, Score=1000, Pubmed Id: 17510944, UMLKSK CUI: C0035258
HumanNOS14842nitric oxide synthase 1 (neuronal)
img GENERIF, Score=1000, Pubmed Id: 18058820, UMLKSK CUI: C0035258
HumanATXN34287ataxin 3
img GAD, Score=1000, Pubmed Id: 16389595, UMLKSK CUI: C0035258
img GAD, Score=1000, Pubmed Id: 14746390, UMLKSK CUI: C0035258
HumanMAOB4129monoamine oxidase B
img GAD, Score=1000, Pubmed Id: 12136060, UMLKSK CUI: C0035258
HumanMAOA4128monoamine oxidase A
img GAD, Score=1000, Pubmed Id: 12136060, UMLKSK CUI: C0035258
HumanEPO2056erythropoietin
img GENERIF, Score=1000, Pubmed Id: 17984928, UMLKSK CUI: C0035258
HumanCACNA1A773calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
img GAD, Score=1000, Pubmed Id: 16389595, UMLKSK CUI: C0035258
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0035258Restless Legs Syndrome0self