Human | TRPV2 | 51393 | transient receptor potential cation channel, subfamily V, member 2 | The TRPV2 ARD provides the first structural insight into a domain that coordinates nociceptive sensory transduction and is likely to be a prototype for other TRPV channel ARDs |
Human | ADAMTS13 | 11093 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 | Acute respiratory distress syndrome (uncommon) |
Human | VEGFA | 7422 | vascular endothelial growth factor A | Title:|Association:Not Found|Conclusion:These data support a role for VEGF in the pathogenesis of ARDS and its associated physiological derangement. |
Human | SCGB1A1 | 7356 | secretoglobin, family 1A, member 1 (uteroglobin) | Title:Evaluation of the -26G>A CC16 polymorphism in acute respiratory distress syndrome.|Association:Not Found|Conclusion:The CC16 -26G>A polymorphism does not affect the susceptibility to and the outcome of ARDS. |
Human | TLR3 | 7098 | toll-like receptor 3 | TLR3 has a major role in the development of ARDS-like pathology in the absence of a viral pathogen |
Human | TGFB1 | 7040 | transforming growth factor, beta 1 | expressed in acute respiratory distress syndrome |
Human | TFPI | 7035 | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | Levels of intra-alveolar TFPI in adult respiratory distress syndrome are not sufficient to block intra-alveolar TF procoagulant activity due to truncation and inactivation of intra-alveolar TFPI |
Human | SFTPD | 6441 | surfactant protein D | serum SP-D levels may serve as a good diagnostic indicator of acute respiratory distress syndrome in patients with sepsis |
Human | SFTPB | 6439 | surfactant protein B | dimeric SP-B(1-25) is more efficient in restoring lung function in neonatal RDS and ARDS than monomeric SP-B(1-25) surfactant Title:|Association:Not Found|Conclusion:Not Found Title:Polymorphism in the Surfactant Protein-B Gene, Gender, and the Risk of Direct Pulmonary Injury and ARDS|Association:Not Found|Conclusion:The variant polymorphism of the SP-B gene is associated with ARDS and with direct pulmonary injury in women, but not in men. Further study is needed to confirm the association between the variant SP-B gene, and gender, ARDS, and direct pulmonary injury. The variant polymorphism of the SP-B gene is associated with ARDS and with direct pulmonary injury in women In this study, the variable nuclear tandem repeat surfactant protein B gene polymorphism in intron 4 is associated with an increased 60 day mortality in acute respiratory distress syndrome |
Human | PI3 | 5266 | peptidase inhibitor 3, skin-derived | Results of a genome-wide expression analysis in blood identify pre-elafin as a biomarker in acute respiratory distress syndrome |
Human | SERPINE1 | 5054 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | Factor activator-like protein hyaluronan-binding protein 2 inhibits vascular smooth muscle cell proliferation in acute respiratory distress syndrome |
Human | NOS3 | 4846 | nitric oxide synthase 3 (endothelial cell) | We were unable to show a relationship between eNOS gene intron 4 a/b VNTR polymorphism and MODS, ARDS, mortality and shock |
Human | NFKB1 | 4790 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | insertion/deletion polymorphism in the promoter of NFKB1 influences the severity but not the mortality of acute respiratory distress syndrome |
Human | MIF | 4282 | macrophage migration inhibitory factor (glycosylation-inhibiting factor) | The serum level of MIF and PBMC MIF expression increased in acute respiratory distress syndrome patients |
Human | IL6 | 3569 | interleukin 6 (interferon, beta 2) | IL6 gene-wide haplotype is associated with susceptibility to adult respiratory distress syndrome |
Human | HSD11B2 | 3291 | hydroxysteroid (11-beta) dehydrogenase 2 | An increase in the expression of 11 beta-HSD2 may result in faster glucocorticoid breakdown in lung cells in patients with acute respiratory distress syndrome (ARDS) |
Human | HABP2 | 3026 | hyaluronan binding protein 2 | FSAP is a novel plasma-derived serine protease structurally homologous to tissue-type and urokinase-type plasminogen activators present in bronchoalveolar lavage fluids from patients with acute respiratory distress syndrome |
Human | F3 | 2152 | coagulation factor III (thromboplastin, tissue factor) | Levels of intra-alveolar TFPI in adult respiratory distress syndrome are not sufficient to block intra-alveolar TF procoagulant activity due to truncation and inactivation of intra-alveolar TFPI results confirm that the procoagulant properties of bronchoalveolar lavage fluid (BALF) from Acute Respiratory Distress Syndrome patients are the result of TF induction & indicate that BALF neutrophils are a main source of TF in intra-alveolar fluid |
Human | EDN1 | 1906 | endothelin 1 | In patients with acute lung injury/ARDS, ET-1 is produced mainly in the lung and is associated not only with pulmonary vasoconstriction but also the development of permeability oedema, leading to the impairment of oxygenation |
Human | ACE | 1636 | angiotensin I converting enzyme | Title:|Association:Y|Conclusion:Not Found ACE insertion/deletion polymorphism is not associated with susceptibility and outcome in sepsis and acute respiratory distress syndrome ACE I/D polymorphism is a risk factor for mortality in acute respiratory distress syndrome |
Human | CMA1 | 1215 | chymase 1, mast cell | Title:|Association:Y|Conclusion:Not Found |
Human | FASLG | 356 | Fas ligand (TNF superfamily, member 6) | fas ligand is up-regulated in acute lung injury and the acute respiratory distress syndrome |
Human | FAS | 355 | Fas cell surface death receptor | fas Receptors are up-regulated in acute lung injury and the acute respiratory distress syndrome |