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Details
Link-It Detail - Disease - Reperfusion Injury
Debug Stats
  • ### Total Build Time: 95 ms 50.458 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 383 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 432 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=2 ms Completed: 2 ms rowSize= 998 bytes
  • CONCEPT_CHILDREN gt=2 ms Completed: 2 ms rowSize= 1,010 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 2.808 KB
  • CONCEPT_RELATIONSHIPS gt=72 ms Completed: 72 ms rowSize= 13.439 KB
  • CONCEPT_GENES gt=14 ms Completed: 14 ms rowSize= 30.091 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.152 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
Reperfusion Injury C0035126
Damage, Reperfusion
Definition (1)
Adverse functional, metabolic, or structural changes in ischemic tissues resulting from the restoration of blood flow to the tissue (REPERFUSION), including swelling; HEMORRHAGE; NECROSIS; and damage from FREE RADICALS. The most common instance is MYOCARDIAL REPERFUSION INJURY.
Semantic Types (1)
Injury or Poisoning (T037)
Parents (2)
img Postoperative Complications C0032787
img Vascular Diseases C0042373
Children (2)
img Myocardial Reperfusion Injury C0027055
img Primary Graft Dysfunction C0948031
Ancestral Roots
RootRoot Plus OneDepthParent
img Pathological Conditions, Signs and Symptoms C0039058img Pathologic Processes C00306604img Postoperative Complications C0032787
img Cardiovascular Diseases C0007222img Vascular Diseases C00423733img Vascular Diseases C0042373
Relationships (256)

Relation Types:
diso_​to_​anat : 64
diso_​to_​chem : 110
diso_​to_​diso : 60
diso_​to_​phen : 2
diso_​to_​phys : 20


Relationships:
none : 248
entry_​version_​of : 1
may_​prevent : 7
Page Size
Current 25
  Page 1 of 11
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANAT551img Liver C0023884
DISO_to_ANAT457img Liver C0023884
DISO_to_ANAT456img Kidney C0022646
DISO_to_DISO387img Brain Ischemia C0007786
DISO_to_DISO356img Complication Aspects C1171258
DISO_to_ANAT296img Kidney C0022646
DISO_to_DISO283img Ischemia C0022116
DISO_to_CHEM256img Antioxidants C0003402
DISO_to_DISO240img Brain Ischemia C0007786
DISO_to_DISO234img Ischemia C0022116
DISO_to_DISO232img Complication Aspects C1171258
DISO_to_CHEM225img Agents, Neuroprotective C0242912
DISO_to_PHEN225img genetic aspects C0017399
DISO_to_PHYS224img Apoptosis C0162638
DISO_to_ANAT222img In Blood C0005768
DISO_to_DISO184img Kidney Diseases C0022658
DISO_to_ANAT176img Intestines C0021853
DISO_to_CHEM174img Antioxidants C0003402
DISO_to_DISO165img Oxidative Stress C0242606
DISO_to_DISO156img Liver Diseases C0023895
DISO_to_DISO154img Acute kidney injury C2609414
DISO_to_PHYS151img Apoptosis C0162638
DISO_to_ANAT148img Lung C0024109
DISO_to_ANAT147img In Blood C0005768
DISO_to_ANAT140img Lung C0024109
Genes (36)

Species:
human : 36
Page Size
Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanRETN56729resistin
img GENERIF, Score=923, Pubmed Id: 16934751, UMLKSK CUI: C0035126
HumanAPOM55937apolipoprotein M
img GENERIF, Score=923, Pubmed Id: 17112825, UMLKSK CUI: C0035126
HumanIQGAP18826IQ motif containing GTPase activating protein 1
img GENERIF, Score=923, Pubmed Id: 16622255, UMLKSK CUI: C0035126
HumanAOC38639amine oxidase, copper containing 3
img GENERIF, Score=1000, Pubmed Id: 18991279, UMLKSK CUI: C0035126
HumanVWF7450von Willebrand factor
img GENERIF, Score=901, Pubmed Id: 17275499, UMLKSK CUI: C0035126
HumanTHBD7056thrombomodulin
img GENERIF, Score=901, Pubmed Id: 17275499, UMLKSK CUI: C0035126
HumanSOD16647superoxide dismutase 1, soluble
img GENERIF, Score=1000, Pubmed Id: 17292357, UMLKSK CUI: C0035126
HumanSLC8A16546solute carrier family 8 (sodium/calcium exchanger), member 1
img GENERIF, Score=902, Pubmed Id: 17912271, UMLKSK CUI: C0035126
HumanSELP6403selectin P (granule membrane protein 140kDa, antigen CD62)
img GENERIF, Score=901, Pubmed Id: 17275499, UMLKSK CUI: C0035126
HumanSAT16303spermidine/spermine N1-acetyltransferase 1
img GENERIF, Score=923, Pubmed Id: 15213272, UMLKSK CUI: C0035126
HumanPRKCD5580protein kinase C, delta
img GENERIF, Score=668, Pubmed Id: 15167677, UMLKSK CUI: C0035126
HumanPPARG5468peroxisome proliferator-activated receptor gamma
img GENERIF, Score=923, Pubmed Id: 15919430, UMLKSK CUI: C0035126
HumanNOS34846nitric oxide synthase 3 (endothelial cell)
INFERRED, Score=800, UMLKSK CUI: C0035126
HumanNFE2L24780nuclear factor, erythroid 2-like 2
img GENERIF, Score=923, Pubmed Id: 18049112, UMLKSK CUI: C0035126
HumanNDUFB24708NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
img GENERIF, Score=884, Pubmed Id: 14718445, UMLKSK CUI: C0035126
HumanMMP94318matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
img GENERIF, Score=861, Pubmed Id: 14697951, UMLKSK CUI: C0035126
img GENERIF, Score=1000, Pubmed Id: 14983226, UMLKSK CUI: C0035126
HumanMMP24313matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
img GENERIF, Score=861, Pubmed Id: 14697951, UMLKSK CUI: C0035126
HumanMIF4282macrophage migration inhibitory factor (glycosylation-inhibiting factor)
img GENERIF, Score=1000, Pubmed Id: 18235500, UMLKSK CUI: C0035126
HumanLCN23934lipocalin 2
img GENERIF, Score=1000, Pubmed Id: 15711640, UMLKSK CUI: C0035126
HumanITGB23689integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
img GENERIF, Score=861, Pubmed Id: 12200369, UMLKSK CUI: C0035126
HumanIL103586interleukin 10
img GENERIF, Score=1000, Pubmed Id: 14999688, UMLKSK CUI: C0035126
img GENERIF, Score=845, Pubmed Id: 11986609, UMLKSK CUI: C0035126
HumanCXCR23579chemokine (C-X-C motif) receptor 2
img GENERIF, Score=845, Pubmed Id: 16272353, UMLKSK CUI: C0035126
HumanHSPA43308heat shock 70kDa protein 4
img GENERIF, Score=1000, Pubmed Id: 17311516, UMLKSK CUI: C0035126
HumanHMOX13162heme oxygenase (decycling) 1
img GENERIF, Score=1000, Pubmed Id: 15849554, UMLKSK CUI: C0035126
HumanHIF1A3091hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
img GENERIF, Score=1000, Pubmed Id: 17519789, UMLKSK CUI: C0035126
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0035126Reperfusion Injury0self