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Details
Link-It Detail - Disease - Purpura, Schoenlein-Henoch
Debug Stats
  • ### Total Build Time: 231 ms 51.738 KB
  • CONCEPT_NAME gt=12 ms Completed: 12 ms rowSize= 405 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 562 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 232 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=9 ms Completed: 9 ms rowSize= 1.808 KB
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=5 ms Completed: 5 ms rowSize= 9.163 KB
  • CONCEPT_RELATIONSHIPS gt=167 ms Completed: 167 ms rowSize= 13.387 KB
  • CONCEPT_GENES gt=36 ms Completed: 36 ms rowSize= 25.015 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.160 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
Purpura, Schoenlein-Henoch C0034152
Henoch-Schoenlein Purpura
Definition (1)
A systemic non-thrombocytopenic purpura caused by HYPERSENSITIVITY VASCULITIS and deposition of IGA-containing IMMUNE COMPLEXES within the blood vessels throughout the body, including those in the kidney (KIDNEY GLOMERULUS). Clinical symptoms include URTICARIA; ERYTHEMA; ARTHRITIS; GASTROINTESTINAL HEMORRHAGE; and renal involvement. Most cases are seen in children after acute upper respiratory infections.
Semantic Types (2)
Finding (T033)
Disease or Syndrome (T047)
Parents (4)
img Immune Complex Diseases C0020951
img Hemostatic Disorders C0600502
img Vasculitis C0042384
img Purpura C0034150
Ancestral Roots
RootRoot Plus OneDepthParent
img Immune System Diseases C0021053img Hypersensitivity C00205174img Immune Complex Diseases C0020951
img Hemic and Lymphatic Diseases C0018981img Hematologic Diseases C00189395img Hemostatic Disorders C0600502
img Cardiovascular Diseases C0007222img Vascular Diseases C00423734img Hemostatic Disorders C0600502
img Cardiovascular Diseases C0007222img Vascular Diseases C00423734img Vasculitis C0042384
img Pathological Conditions, Signs and Symptoms C0039058img Signs and Symptoms C00370885img Purpura C0034150
img Hemic and Lymphatic Diseases C0018981img Hematologic Diseases C00189395img Purpura C0034150
img Pathological Conditions, Signs and Symptoms C0039058img Pathologic Processes C00306605img Purpura C0034150
Relationships (67)

Relation Types:
diso_​to_​anat : 6
diso_​to_​chem : 9
diso_​to_​diso : 47
diso_​to_​phen : 3
diso_​to_​phys : 2


Relationships:
none : 50
classifies : 2
is_​associated_​anatomic_​site_​of : 2
isa : 3
mapped_​to : 8
permuted_​term_​of : 1
used_​for : 1
Page Size
Current 25
  Page 1 of 3
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO301img Complication Aspects C1171258
DISO_to_DISO206img Complication Aspects C1171258
DISO_to_DISO76img Nephritis C0027697
DISO_to_ANAT42img In Blood C0005768
DISO_to_PHEN39img genetic aspects C0017399
DISO_to_DISO38img Nephritis C0027697
DISO_to_ANAT29img In Blood C0005768
DISO_to_PHEN29img genetic aspects C0017399
DISO_to_DISO27img Glomerulonephritis, IGA C0017661
DISO_to_DISO23img Meningococcal Infections C0025303
DISO_to_DISO20img chemically induced C0007994
DISO_to_CHEM18img Immunosuppressive Agents C0021081
DISO_to_DISO18img Kidney Diseases C0022658
DISO_to_DISO17img Glomerulonephritis C0017658
DISO_to_DISO17img chemically induced C0007994
DISO_to_CHEM16img GLUCOCORTICOIDS C0017710
DISO_to_DISO16img BLEEDING GASTROINTESTINAL C0017181
DISO_to_DISO16img Glomerulonephritis, IGA C0017661
DISO_to_DISO16img Hemorrhage C0019080
DISO_to_CHEM15img Immunoglobulin A C0020835
DISO_to_DISO15img Abdominal Pain C0000737
DISO_to_ANAT14img Kidney C0022646
DISO_to_DISO14img Nephrotic Syndrome C0027726
DISO_to_DISO14img Sepsis C0243026
DISO_to_PHYS14img Genetic Polymorphism C0032529
Genes (22)

Species:
human : 22
SpeciesGeneGeneIdGene NameEvidence
HumanPTPN2226191protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
img GENERIF, Score=1000, Pubmed Id: 18078626, UMLKSK CUI: C0034152
HumanNPHS27827nephrosis 2, idiopathic, steroid-resistant (podocin)
img GENERIF, Score=756, Pubmed Id: 17393177, UMLKSK CUI: C0034152
HumanSCGB1A17356secretoglobin, family 1A, member 1 (uteroglobin)
img GENERIF, Score=923, Pubmed Id: 16703373, UMLKSK CUI: C0034152
HumanSELL6402selectin L
img OMIM, Score=716, UMLKSK CUI: C0034152
HumanSELE6401selectin E
img OMIM, Score=716, UMLKSK CUI: C0034152
HumanPON15444paraoxonase 1
img GENERIF, Score=884, Pubmed Id: 17646900, UMLKSK CUI: C0034152
HumanPIGR5284polymeric immunoglobulin receptor
img OMIM, Score=716, UMLKSK CUI: C0034152
HumanNOS34846nitric oxide synthase 3 (endothelial cell)
img GENERIF, Score=1000, Pubmed Id: 14760800, UMLKSK CUI: C0034152
HumanNOS24843nitric oxide synthase 2, inducible
img GENERIF, Score=734, Pubmed Id: 15940772, UMLKSK CUI: C0034152
HumanMMP94318matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
img GENERIF, Score=1000, Pubmed Id: 16467043, UMLKSK CUI: C0034152
HumanMET4233met proto-oncogene
img GENERIF, Score=756, Pubmed Id: 18273647, UMLKSK CUI: C0034152
HumanIL63569interleukin 6 (interferon, beta 2)
img GENERIF, Score=694, Pubmed Id: 17428355, UMLKSK CUI: C0034152
HumanIL1B3553interleukin 1, beta
img GENERIF, Score=1000, Pubmed Id: 14760799, UMLKSK CUI: C0034152
HumanHLA-DRB13123
img GENERIF, Score=1000, Pubmed Id: 18412308, UMLKSK CUI: C0034152
img GENERIF, Score=1000, Pubmed Id: 12022354, UMLKSK CUI: C0034152
img GENERIF, Score=756, Pubmed Id: 18449568, UMLKSK CUI: C0034152
HumanHLA-DQA13117
img GAD, Score=1000, Pubmed Id: 11836690, UMLKSK CUI: C0034152
HumanHLA-B3106
img GENERIF, Score=679, Pubmed Id: 17487448, UMLKSK CUI: C0034152
HumanCTLA41493cytotoxic T-lymphocyte-associated protein 4
img GENERIF, Score=1000, Pubmed Id: 18449568, UMLKSK CUI: C0034152
HumanCP1356ceruloplasmin (ferroxidase)
img GENERIF, Score=1000, Pubmed Id: 17404760, UMLKSK CUI: C0034152
HumanCAT847catalase
img GENERIF, Score=1000, Pubmed Id: 17646900, UMLKSK CUI: C0034152
HumanC4B721complement component 4B (Chido blood group)
img GENERIF, Score=756, Pubmed Id: 15787745, UMLKSK CUI: C0034152
HumanAGT183angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
img GENERIF, Score=1000, Pubmed Id: 16521052, UMLKSK CUI: C0034152
HumanADM133adrenomedullin
img GENERIF, Score=1000, Pubmed Id: 12920627, UMLKSK CUI: C0034152
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0034152Purpura, Schoenlein-Henoch0self