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Details
Link-It Detail - Disease - Pulmonary Fibrosis
Debug Stats
  • ### Total Build Time: 315 ms 51.751 KB
  • CONCEPT_NAME gt=5 ms Completed: 5 ms rowSize= 334 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 885 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 549 bytes
  • CONCEPT_CHILDREN gt=2 ms Completed: 2 ms rowSize= 567 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.500 KB
  • CONCEPT_RELATIONSHIPS gt=270 ms Completed: 270 ms rowSize= 14.243 KB
  • CONCEPT_GENES gt=31 ms Completed: 31 ms rowSize= 32.364 KB
  • CONCEPT_XREFS gt=3 ms Completed: 3 ms rowSize= 1.152 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Pulmonary Fibrosis C0034069
Definition (1)

Pulmonary fibrosis harms the tissues deep in your lungs. The air sacs in your lungs and their supporting structures become scarred and make your lungs thick and stiff. That makes it hard for you to catch your breath, and your blood may not get enough oxygen.

One cause of pulmonary fibrosis is interstitial lung disease. Interstitial lung disease is the name for a large group of diseases that inflame or scar the lungs. Pulmonary fibrosis is also associated with some connective tissue diseases. It can be a side effect of a medicine. Sometimes no one knows the cause of the disease. Smoking can boost your risk or make your illness worse

Semantic Types (1)
Disease or Syndrome (T047)
Parents (1)
img Lung Diseases C0024115
Children (1)
img Idiopathic Pulmonary Fibrosis C1800706
Ancestral Roots
RootRoot Plus OneDepthParent
img Respiratory Tract Diseases C0035242img Lung Diseases C00241153img Lung Diseases C0024115
Relationships (167)

Relation Types:
diso_​to_​anat : 20
diso_​to_​chem : 58
diso_​to_​diso : 81
diso_​to_​phen : 2
diso_​to_​phys : 6


Relationships:
none : 123
associated_​with : 1
is_​associated_​anatomic_​site_​of : 3
isa : 25
mapped_​to : 5
may_​treat : 7
related_​to : 2
used_​for : 1
Page Size
Current 25
  Page 1 of 7
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO413img chemically induced C0007994
DISO_to_DISO291img chemically induced C0007994
DISO_to_ANAT198img Lung C0024109
DISO_to_PHEN167img genetic aspects C0017399
DISO_to_ANAT154img Lung C0024109
DISO_to_PHEN133img genetic aspects C0017399
DISO_to_DISO129img Complication Aspects C1171258
DISO_to_DISO123img Complication Aspects C1171258
DISO_to_CHEM110img Bleomycin C0005740
DISO_to_CHEM86img Bleomycin C0005740
DISO_to_DISO83img Scleroderma, Systemic C0036421
DISO_to_DISO81img Lung Diseases, Interstitial C0206062
DISO_to_ANAT76img Fibroblasts C0016030
DISO_to_DISO72img Lung Diseases, Interstitial C0206062
DISO_to_ANAT56img In Blood C0005768
DISO_to_ANAT55img Fibroblasts C0016030
DISO_to_DISO54img Pneumonia C0032285
DISO_to_DISO53img Scleroderma, Systemic C0036421
DISO_to_DISO44img Hypertension, Pulmonary C0020542
DISO_to_DISO44img Lung Neoplasms C0024121
DISO_to_ANAT42img In Blood C0005768
DISO_to_CHEM40img Transforming Growth Factor beta C0040690
DISO_to_CHEM39img Interferon Type II C0021745
DISO_to_CHEM38img Transforming Growth Factor beta1 C1704256
DISO_to_ANAT37img Bronchoalveolar Lavage Fluid C0006279
Genes (51)

Species:
human : 50
mouse : 1
Page Size
Current 25
  Page 1 of 3
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
MouseARG1383arginase 1
img NCI, Score=801, Pubmed Id: 15292275, UMLKSK CUI: C0034069
HumanSFTPA1653509surfactant protein A1
img GENERIF, Score=1000, Pubmed Id: 13680361, UMLKSK CUI: C0034069
img GAD, Score=1000, Pubmed Id: 13680361, UMLKSK CUI: C0034069
HumanHPS489781Hermansky-Pudlak syndrome 4
img GENERIF, Score=901, Pubmed Id: 12664304, UMLKSK CUI: C0034069
HumanROBO454538roundabout, axon guidance receptor, homolog 4 (Drosophila)
img GENERIF, Score=1000, Pubmed Id: 17496152, UMLKSK CUI: C0034069
HumanTINF226277TERF1 (TRF1)-interacting nuclear factor 2
img OMIM, Score=1000, UMLKSK CUI: C0034069
HumanHEY123462hairy/enhancer-of-split related with YRPW motif 1
img GENERIF, Score=1000, Pubmed Id: 17496152, UMLKSK CUI: C0034069
HumanSLIT29353slit homolog 2 (Drosophila)
img GENERIF, Score=1000, Pubmed Id: 17496152, UMLKSK CUI: C0034069
HumanAP3B18546adaptor-related protein complex 3, beta 1 subunit
img OMIM, Score=1000, UMLKSK CUI: C0034069
HumanTNF7124tumor necrosis factor
img GENERIF, Score=1000, Pubmed Id: 12816730, UMLKSK CUI: C0034069
img GAD, Score=833, Pubmed Id: 12030733, UMLKSK CUI: C0034069
HumanTGFB17040transforming growth factor, beta 1
img GENERIF, Score=1000, Pubmed Id: 15133032, UMLKSK CUI: C0034069
img GENERIF, Score=1000, Pubmed Id: 12858451, UMLKSK CUI: C0034069
HumanTERT7015telomerase reverse transcriptase
img OMIM, Score=1000, UMLKSK CUI: C0034069
img GENERIF, Score=861, Pubmed Id: 18635888, UMLKSK CUI: C0034069
HumanTERC7012telomerase RNA component
img OMIM, Score=1000, UMLKSK CUI: C0034069
HumanSGK16446serum/glucocorticoid regulated kinase 1
img GENERIF, Score=1000, Pubmed Id: 12077559, UMLKSK CUI: C0034069
HumanSFTPD6441surfactant protein D
img GAD, Score=1000, Pubmed Id: 13680361, UMLKSK CUI: C0034069
HumanSFTPC6440surfactant protein C
img GAD, Score=1000, Pubmed Id: 13680361, UMLKSK CUI: C0034069
HumanSFTPB6439surfactant protein B
img GAD, Score=1000, Pubmed Id: 13680361, UMLKSK CUI: C0034069
HumanSFTPA2B6436
img GAD, Score=1000, Pubmed Id: 13680361, UMLKSK CUI: C0034069
HumanCXCL126387chemokine (C-X-C motif) ligand 12
img GENERIF, Score=901, Pubmed Id: 17174272, UMLKSK CUI: C0034069
HumanCCL186362chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
img GENERIF, Score=698, Pubmed Id: 17469163, UMLKSK CUI: C0034069
HumanCCL116356chemokine (C-C motif) ligand 11
img GENERIF, Score=827, Pubmed Id: 17620002, UMLKSK CUI: C0034069
HumanCCL56352chemokine (C-C motif) ligand 5
img GENERIF, Score=827, Pubmed Id: 17620002, UMLKSK CUI: C0034069
HumanCCL26347chemokine (C-C motif) ligand 2
img GENERIF, Score=1000, Pubmed Id: 17431224, UMLKSK CUI: C0034069
HumanSERPINB36317serpin peptidase inhibitor, clade B (ovalbumin), member 3
img GENERIF, Score=1000, Pubmed Id: 18078639, UMLKSK CUI: C0034069
HumanPRKCD5580protein kinase C, delta
img GENERIF, Score=1000, Pubmed Id: 15133032, UMLKSK CUI: C0034069
HumanPPARG5468peroxisome proliferator-activated receptor gamma
img GENERIF, Score=1000, Pubmed Id: 18317437, UMLKSK CUI: C0034069
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0034069Pulmonary Fibrosis0self