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Details
Link-It Detail - Disease - Adenomatous Polyposis Coli
Debug Stats
  • ### Total Build Time: 316 ms 81.299 KB
  • CONCEPT_NAME gt=6 ms Completed: 6 ms rowSize= 350 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 337 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=12 ms Completed: 12 ms rowSize= 2.263 KB
  • CONCEPT_CHILDREN gt=8 ms Completed: 8 ms rowSize= 554 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=71 ms Completed: 71 ms rowSize= 13.053 KB
  • CONCEPT_RELATIONSHIPS gt=160 ms Completed: 160 ms rowSize= 17.102 KB
  • CONCEPT_GENES gt=52 ms Completed: 52 ms rowSize= 46.300 KB
  • CONCEPT_XREFS gt=6 ms Completed: 6 ms rowSize= 1.160 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Adenomatous Polyposis Coli C0032580
Definition (1)
An inherited condition in which numerous polyps (growths that protrude from mucous membranes) form on the inside walls of the colon and rectum. It increases the risk for colon cancer.
Semantic Types (1)
Neoplastic Process (T191)
Parents (5)
img Intestinal Polyposis C1257915
img Adenomatous Polyps C0206677
img Colonic Neoplasms C0009375
img Neoplastic Syndromes, Hereditary C0027672
img Colorectal Neoplasms C0009404
Children (1)
img Gardner Syndrome C0017097
Ancestral Roots
RootRoot Plus OneDepthParent
img Digestive System Diseases C0012242img Gastrointestinal Diseases C00171785img Intestinal Polyposis C1257915
img Neoplasms C0027651img Neoplasms by Histologic Type C00276526img Adenomatous Polyps C0206677
img Digestive System Diseases C0012242img Gastrointestinal Diseases C00171787img Colonic Neoplasms C0009375
img Digestive System Diseases C0012242img Digestive System Neoplasms C00122437img Colonic Neoplasms C0009375
img Neoplasms C0027651img Neoplasms by Site C00276538img Colonic Neoplasms C0009375
img Neoplasms C0027651img Neoplastic Syndromes, Hereditary C00276723img Neoplastic Syndromes, Hereditary C0027672
img Congenital, Hereditary, and Neonatal Diseases and Abnormalities C0027612img Genetic Diseases, Inborn C09501234img Neoplastic Syndromes, Hereditary C0027672
img Digestive System Diseases C0012242img Gastrointestinal Diseases C00171786img Colorectal Neoplasms C0009404
img Digestive System Diseases C0012242img Digestive System Neoplasms C00122436img Colorectal Neoplasms C0009404
img Neoplasms C0027651img Neoplasms by Site C00276537img Colorectal Neoplasms C0009404
Relationships (98)

Relation Types:
diso_​to_​anat : 20
diso_​to_​chem : 19
diso_​to_​diso : 48
diso_​to_​gene : 2
diso_​to_​phen : 2
diso_​to_​phys : 7


Relationships:
none : 51
associated_​genetic_​condition : 1
associated_​with : 2
disease_​has_​associated_​disease : 3
gene_​product_​malfunction_​associated_​with_​disease : 2
is_​abnormal_​cell_​of_​disease : 3
is_​associated_​anatomic_​site_​of : 2
is_​associated_​disease_​of : 1
is_​finding_​of_​disease : 6
is_​normal_​cell_​origin_​of_​disease : 3
is_​normal_​tissue_​origin_​of_​disease : 4
is_​not_​abnormal_​cell_​of_​disease : 1
is_​primary_​anatomic_​site_​of_​disease : 2
isa : 2
location_​of : 1
mapped_​to : 2
may_​be_​associated_​disease_​of_​disease : 1
may_​be_​finding_​of_​disease : 4
may_​treat : 5
permuted_​term_​of : 1
used_​for : 1
Page Size
Current 25
  Page 1 of 4
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_PHEN373img genetic aspects C0017399
DISO_to_PHEN353img genetic aspects C0017399
DISO_to_GENE117img Genes, APC C0162832
DISO_to_DISO111img Complication Aspects C1171258
DISO_to_DISO109img Complication Aspects C1171258
DISO_to_DISO106img COLORECTAL NEOPL C0009404
DISO_to_GENE105img APC gene C0162832
DISO_to_DISO83img COLORECTAL NEOPL C0009404
DISO_to_PHYS65img Mutation C0026882
DISO_to_DISO61img Colonic Pouche C0086783
DISO_to_CHEM58img DNA Glycosylases C0114612
DISO_to_DISO57img Adenoma C0001430
DISO_to_PHYS51img Germ-Line Mutation C0206530
DISO_to_DISO50img Colitis, Ulcerative C0009324
DISO_to_CHEM48img Adenomatous Polyposis Coli Protein C0753723
DISO_to_DISO45img Colorectal Neoplasms, Hereditary Nonpolyposis C0009405
DISO_to_PHYS45img Mutation C0026882
DISO_to_DISO42img Adenoma C0001430
DISO_to_DISO41img DUODENAL NEOPL C0013291
DISO_to_DISO40img Colorectal Neoplasms, Hereditary Nonpolyposis C0009405
DISO_to_DISO39img Colitis, Ulcerative C0009324
DISO_to_DISO38img Adenocarcinoma C0001418
DISO_to_DISO37img Fibromatosis, Aggressive C0079218
DISO_to_CHEM35img DNA Glycosylases C0114612
DISO_to_PHYS34img Germ-Line Mutation C0206530
Genes (90)

Species:
human : 86
mouse : 4
Page Size
Current 25
  Page 1 of 4
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
MouseANAPC229882anaphase promoting complex subunit 2
img NCI, Score=801, Pubmed Id: 10516441, UMLKSK CUI: C0032580
MouseNTN19423netrin 1
img NCI, Score=801, Pubmed Id: 15343335, UMLKSK CUI: C0032580
MouseREEP57905receptor accessory protein 5
img NCI, Score=801, Pubmed Id: 8647449, UMLKSK CUI: C0032580
MouseCYP26A11592cytochrome P450, family 26, subfamily A, polypeptide 1
img NCI, Score=801, Pubmed Id: 16885356, UMLKSK CUI: C0032580
HumanAGRN375790agrin
img NCI, Score=801, Pubmed Id: 14502292, UMLKSK CUI: C0032580
HumanENPP7339221ectonucleotide pyrophosphatase/phosphodiesterase 7
img NCI, Score=801, Pubmed Id: 12774245, UMLKSK CUI: C0032580
img NCI, Score=801, Pubmed Id: 10496347, UMLKSK CUI: C0032580
img NCI, Score=801, Pubmed Id: 12774245, UMLKSK CUI: C0032580
HumanTUBA1C84790tubulin, alpha 1c
img NCI, Score=801, Pubmed Id: 11593399, UMLKSK CUI: C0032580
img NCI, Score=801, Pubmed Id: 9654054, UMLKSK CUI: C0032580
HumanCTNNBIP156998catenin, beta interacting protein 1
img NCI, Score=801, Pubmed Id: 12124804, UMLKSK CUI: C0032580
HumanATP8A251761ATPase, aminophospholipid transporter, class I, type 8A, member 2
img NCI, Score=801, Pubmed Id: 15516847, UMLKSK CUI: C0032580
HumanANAPC229882anaphase promoting complex subunit 2
img NCI, Score=801, Pubmed Id: 15018807, UMLKSK CUI: C0032580
img NCI, Score=801, Pubmed Id: 7645991, UMLKSK CUI: C0032580
img NCI, Score=801, Pubmed Id: 11691822, UMLKSK CUI: C0032580
img NCI, Score=801, Pubmed Id: 10021369, UMLKSK CUI: C0032580
HumanPPP1R15A23645protein phosphatase 1, regulatory subunit 15A
img NCI, Score=801, Pubmed Id: 11198475, UMLKSK CUI: C0032580
HumanAPC210297adenomatosis polyposis coli 2
img NCI, Score=801, Pubmed Id: 15018807, UMLKSK CUI: C0032580
img GENERIF, Score=1000, Pubmed Id: 18157572, UMLKSK CUI: C0032580
img NCI, Score=801, Pubmed Id: 11691822, UMLKSK CUI: C0032580
HumanDOCK49732dedicator of cytokinesis 4
img GENERIF, Score=861, Pubmed Id: 18641688, UMLKSK CUI: C0032580
HumanKLF49314Kruppel-like factor 4 (gut)
img NCI, Score=801, Pubmed Id: 10913614, UMLKSK CUI: C0032580
img NCI, Score=801, Pubmed Id: 11521200, UMLKSK CUI: C0032580
HumanDNAJA39093DnaJ (Hsp40) homolog, subfamily A, member 3
img GENERIF, Score=717, Pubmed Id: 17588722, UMLKSK CUI: C0032580
HumanIQGAP18826IQ motif containing GTPase activating protein 1
img NCI, Score=801, Pubmed Id: 17085436, UMLKSK CUI: C0032580
img NCI, Score=801, Pubmed Id: 15890984, UMLKSK CUI: C0032580
img NCI, Score=801, Pubmed Id: 17255093, UMLKSK CUI: C0032580
HumanPLA2G108399phospholipase A2, group X
img NCI, Score=801, Pubmed Id: 8707313, UMLKSK CUI: C0032580
HumanPLA2G68398phospholipase A2, group VI (cytosolic, calcium-independent)
img NCI, Score=801, Pubmed Id: 9458096, UMLKSK CUI: C0032580
HumanFZD78324frizzled family receptor 7
img NCI, Score=801, Pubmed Id: 9707618, UMLKSK CUI: C0032580
HumanAXIN18312axin 1
img GENERIF, Score=1000, Pubmed Id: 12036951, UMLKSK CUI: C0032580
HumanREEP57905receptor accessory protein 5
img NCI, Score=801, Pubmed Id: 8224634, UMLKSK CUI: C0032580
img NCI, Score=801, Pubmed Id: 1651174, UMLKSK CUI: C0032580
img NCI, Score=801, Pubmed Id: 10482959, UMLKSK CUI: C0032580
img NCI, Score=801, Pubmed Id: 14516776, UMLKSK CUI: C0032580
img NCI, Score=801, Pubmed Id: 14516776, UMLKSK CUI: C0032580
img NCI, Score=801, Pubmed Id: 8647449, UMLKSK CUI: C0032580
img NCI, Score=801, Pubmed Id: 8652082, UMLKSK CUI: C0032580
img NCI, Score=801, Pubmed Id: 8276387, UMLKSK CUI: C0032580
HumanXRCC57520X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
img NCI, Score=801, Pubmed Id: 12610503, UMLKSK CUI: C0032580
HumanWNT17471wingless-type MMTV integration site family, member 1
img NCI, Score=801, Pubmed Id: 12213737, UMLKSK CUI: C0032580
HumanVHL7428von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
img GENERIF, Score=1000, Pubmed Id: 17954272, UMLKSK CUI: C0032580
HumanZRSR17310zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1
img NCI, Score=801, Pubmed Id: 9490301, UMLKSK CUI: C0032580
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0032580Adenomatous Polyposis Coli0self