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Details
Link-It Detail - Disease - Polymyalgia Rheumatica
Debug Stats
  • ### Total Build Time: 137 ms 24.234 KB
  • CONCEPT_NAME gt=8 ms Completed: 8 ms rowSize= 342 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 650 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=2 ms Completed: 2 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=6 ms Completed: 6 ms rowSize= 989 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=5 ms Completed: 5 ms rowSize= 5.348 KB
  • CONCEPT_RELATIONSHIPS gt=92 ms Completed: 92 ms rowSize= 10.783 KB
  • CONCEPT_GENES gt=19 ms Completed: 19 ms rowSize= 4.794 KB
  • CONCEPT_XREFS gt=4 ms Completed: 4 ms rowSize= 1.156 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Polymyalgia Rheumatica C0032533
Definition (1)
A syndrome in the elderly characterized by proximal joint and muscle pain, high erythrocyte sedimentation rate, and a self-limiting course. Pain is usually accompanied by evidence of an inflammatory reaction. Women are affected twice as commonly as men and Caucasians more frequently than other groups. The condition is frequently associated with GIANT CELL ARTERITIS and some theories pose the possibility that the two diseases arise from a single etiology or even that they are the same entity.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (2)
img Rheumatic Diseases C0035435
img Muscular Diseases C0026848
Ancestral Roots
RootRoot Plus OneDepthParent
img Musculoskeletal Diseases C0026857img Rheumatic Diseases C00354353img Rheumatic Diseases C0035435
img Skin and Connective Tissue Diseases C0175166img Connective Tissue Diseases C00097824img Rheumatic Diseases C0035435
img Nervous System Diseases C0027765img Neuromuscular Diseases C00278684img Muscular Diseases C0026848
img Musculoskeletal Diseases C0026857img Muscular Diseases C00268483img Muscular Diseases C0026848
Relationships (25)

Relation Types:
diso_​to_​anat : 2
diso_​to_​chem : 5
diso_​to_​diso : 17
diso_​to_​phys : 1


Relationships:
none : 20
classifies : 1
expanded_​form_​of : 1
isa : 1
related_​to : 2
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO74img Giant Cell Arteritis C0039483
DISO_to_DISO55img Giant Cell Arteritis C0039483
DISO_to_DISO52img Complication Aspects C1171258
DISO_to_DISO50img Complication Aspects C1171258
DISO_to_CHEM22img GLUCOCORTICOIDS C0017710
DISO_to_CHEM22img Glucocorticoids C0017710
DISO_to_ANAT21img In Blood C0005768
DISO_to_ANAT19img In Blood C0005768
DISO_to_CHEM16img GLUCOCORTICOIDS C0017710
DISO_to_DISO15img Arthritis, Rheumatoid C0003873
DISO_to_CHEM14img Prednisone C0032952
DISO_to_CHEM13img Antirheumatic Agents C0003191
DISO_to_DISO13img Arthritis, Rheumatoid C0003873
DISO_to_DISOimg Abrupt onset of joint complaint (<24 hours) C0221601
DISO_to_DISOimg ESR Westergren (normal <20 mm female, <30 mm male) C0221699
DISO_to_DISOrelated_toimg Giant Cell Arteritis C0039483
DISO_to_DISOisaimg Giant cell arteritis with polymyalgia rheumatica C0343200
DISO_to_DISOimg Morning stiffness (>1 hour) C0221599
DISO_to_DISOclassifiesimg Other connective tissue disease C0810058
DISO_to_DISOexpanded_form_ofimg Polymyalgia Rheumatica C0032533
DISO_to_DISOimg Shoulder joint or periarticular pain C0221650
DISO_to_DISOimg Symmetrical distribution of synovial swelling (if more than one joint affected) C0221609
DISO_to_DISOrelated_toimg Vasculitis C0042384
DISO_to_DISOimg Weight loss >=10% of body weight C0150908
DISO_to_PHYSimg Patient age at this workup C0150906
Genes (3)

Species:
human : 3
SpeciesGeneGeneIdGene NameEvidence
HumanICAM13383intercellular adhesion molecule 1
img GAD, Score=1000, Pubmed Id: 10813290, UMLKSK CUI: C0032533
img GENERIF, Score=901, Pubmed Id: 11911111, UMLKSK CUI: C0032533
HumanHLA-DRB13123
img GENERIF, Score=901, Pubmed Id: 15305244, UMLKSK CUI: C0032533
HumanCCR51234chemokine (C-C motif) receptor 5 (gene/pseudogene)
img GAD, Score=1000, Pubmed Id: 11781692, UMLKSK CUI: C0032533
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0032533Polymyalgia Rheumatica0self