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Details
Link-It Detail - Disease - Persistent Fetal Circulation Syndrome
Debug Stats
  • ### Total Build Time: 38 ms 19.329 KB
  • CONCEPT_NAME gt=14 ms Completed: 14 ms rowSize= 372 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
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  • Reload Stats
Disease (1)
Persistent Fetal Circulation Syndrome C0031190
Definition (1)
A syndrome of persistent PULMONARY HYPERTENSION in the newborn infant (INFANT, NEWBORN) without demonstrable HEART DISEASES. This neonatal condition can be caused by severe pulmonary vasoconstriction (reactive type), hypertrophy of pulmonary arterial muscle (hypertrophic type), or abnormally developed pulmonary arterioles (hypoplastic type). The newborn patient exhibits CYANOSIS and ACIDOSIS due to the persistence of fetal circulatory pattern of right-to-left shunting of blood through a patent ductus arteriosus (DUCTUS ARTERIOSUS, PATENT) and at times a patent foramen ovale (FORAMEN OVALE, PATENT).
Semantic Types (1)
Disease or Syndrome (T047)
Parents (2)
img Infant, Newborn, Diseases C0021290
img Hypertension, Pulmonary C0020542
Ancestral Roots
RootRoot Plus OneDepthParent
img Congenital, Hereditary, and Neonatal Diseases and Abnormalities C0027612img Infant, Newborn, Diseases C00212903img Infant, Newborn, Diseases C0021290
img Respiratory Tract Diseases C0035242img Lung Diseases C00241154img Hypertension, Pulmonary C0020542
Relationships (23)

Relation Types:
diso_​to_​chem : 11
diso_​to_​diso : 11
diso_​to_​phen : 1


Relationships:
none : 13
alias_​of : 1
classifies : 1
clinically_​similar : 1
mapped_​to : 1
may_​treat : 4
used_​for : 2
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_CHEM23img Nitric Oxide C0028128
DISO_to_CHEM18img 815-816 VASODILATING AGENTS C0042402
DISO_to_CHEM16img Piperazines C0031958
DISO_to_DISO16img Complication Aspects C1171258
DISO_to_CHEM15img 815-816 VASODILATING AGENTS C0042402
DISO_to_CHEM15img Sulfones C0038761
DISO_to_DISO13img Complication Aspects C1171258
DISO_to_CHEM10img Phosphodiesterase Inhibitors C0031638
DISO_to_PHEN9img genetic aspects C0017399
DISO_to_CHEM8img Serotonin Uptake Inhibitors C0162758
DISO_to_DISO6img Anoxia C0003130
DISO_to_DISO6img Diaphragmatic Hernia C0019284
DISO_to_DISO6img Respiratory Distress Syndrome, Newborn C0035220
DISO_to_CHEMmay_treatimg 1H-Imidazole, 4,5-dihydro-2-(phenylmethyl)- C0040373
DISO_to_CHEMmay_treatimg Benzazoline hydrochloride C0770500
DISO_to_CHEMmay_treatimg TOLAZOLINE HCL 25MG ORAL TABLET C0981754
DISO_to_CHEMmay_treatimg TOLAZOLINE HCL 25MG/ML AMPUL (ML) C0774577
DISO_to_DISOmapped_toimg Alveolar capillary dysplasia C2677362
DISO_to_DISOclassifiesimg Cardiac and circulatory congenital anomalies C0810060
DISO_to_DISOused_forimg Congenital cardiovascular disorder C1971810
DISO_to_DISOused_forimg Hypertension, Pulmonary C0020542
DISO_to_DISOclinically_similarimg Hypertension, pulmonary, secondary C0264936
DISO_to_DISOalias_ofimg Persistent Fetal Circulation Syndrome C0031190
Genes (2)

Species:
human : 2
SpeciesGeneGeneIdGene NameEvidence
HumanLYVE110894lymphatic vessel endothelial hyaluronan receptor 1
img GENERIF, Score=1000, Pubmed Id: 16569201, UMLKSK CUI: C0031190
HumanTNF7124tumor necrosis factor
img GENERIF, Score=1000, Pubmed Id: 17194482, UMLKSK CUI: C0031190
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0031190Persistent Fetal Circulation Syndrome0self