Human | CISD2 | 493856 | CDGSH iron sulfur domain 2 | Novel mutation, new phenotypic variant with no diabetes insipidus, presence of peptic ulcer disease, platelet aggregation defect |
Human | TREM1 | 54210 | triggering receptor expressed on myeloid cells 1 | Soluble TREM-1 secreted by the gastric mucosa is an independent mechanism connected to the pathogenesis of peptic ulcer |
Human | IL1F5 | 26525 | interleukin 36 receptor antagonist | INFERRED, Score=800, UMLKSK CUI: C0030920 |
Human | NOD1 | 10392 | nucleotide-binding oligomerization domain containing 1 | NOD1 gene polymorphism increases the risk of peptic ulceration in H. pylori-positive patients |
Human | XRCC1 | 7515 | X-ray repair complementing defective repair in Chinese hamster cells 1 | INFERRED, Score=800, UMLKSK CUI: C0030920 |
Human | VEGFA | 7422 | vascular endothelial growth factor A | INFERRED, Score=800, UMLKSK CUI: C0030920 |
Human | TNF | 7124 | tumor necrosis factor | the combination of bacterial iceA1 and TNF-alpha 238 G to A polymorphism may be a risk factor for peptic ulcer disease in children infected with Helicobacter pylori There were no differences in genotypes and allele frequencies of IL-10 and TNF-A polymorphism between study group with gastric cancer and peptic ulcer diseases and control group |
Human | TLR2 | 7097 | toll-like receptor 2 | INFERRED, Score=800, UMLKSK CUI: C0030920 |
Human | TGFB1 | 7040 | transforming growth factor, beta 1 | findings indicate the Leu10Pro & C-509T polymorphisms may be involved in modulation of expression of TGF-beta1; predisposition to peptic ulcer disease could be linked to particular alleles of this gene |
Human | CCL2 | 6347 | chemokine (C-C motif) ligand 2 | INFERRED, Score=800, UMLKSK CUI: C0030920 |
Human | SCT | 6343 | secretin | Peptic ulceration may be a hormonal (secfretin) deficiency disease |
Human | PTGS2 | 5743 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | INFERRED, Score=800, UMLKSK CUI: C0030920 |
Human | PTGS1 | 5742 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) | The COX-1 A-842G/C50T single-nucleotide polymorphism does not influence the risk for developing peptic ulcer bleeding |
Human | PPARG | 5468 | peroxisome proliferator-activated receptor gamma | Analysis of PPARG polymorphism and Helicobacter pylori infection in gastric adenocarcinoma and peptic ulcer disease is reported |
Human | PLG | 5340 | plasminogen | INFERRED, Score=800, UMLKSK CUI: C0030920 |
Human | PLAT | 5327 | plasminogen activator, tissue | INFERRED, Score=800, UMLKSK CUI: C0030920 |
Human | PGC | 5225 | progastricsin (pepsinogen C) | INFERRED, Score=800, UMLKSK CUI: C0030920 |
Human | SERPINE1 | 5054 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | INFERRED, Score=800, UMLKSK CUI: C0030920 |
Human | OGG1 | 4968 | 8-oxoguanine DNA glycosylase | INFERRED, Score=800, UMLKSK CUI: C0030920 |
Human | NFE2L2 | 4780 | nuclear factor, erythroid 2-like 2 | INFERRED, Score=800, UMLKSK CUI: C0030920 |
Human | LDHA | 3939 | lactate dehydrogenase A | The activity of this enzyme was studied in tissues, erythrocytes, and blood plasma of patients with peptic ulcer both in its uncomplicated course and in the development of complications |
Human | ITGAX | 3687 | integrin, alpha X (complement component 3 receptor 4 subunit) | INFERRED, Score=800, UMLKSK CUI: C0030920 |
Human | ITGAM | 3684 | integrin, alpha M (complement component 3 receptor 3 subunit) | INFERRED, Score=800, UMLKSK CUI: C0030920 |
Human | ITGAL | 3683 | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) | INFERRED, Score=800, UMLKSK CUI: C0030920 |
Human | IL12B | 3593 | interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) | The IL12B 1188 (A-->C) gene polymorphism is not involved in defining the genetic basis of the susceptibility to and final outcome of peptic ulcer disease |