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Details
Link-It Detail - Disease - Peptic Ulcer
Debug Stats
  • ### Total Build Time: 66 ms 47.879 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 322 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 563 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=5 ms Completed: 5 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=2 ms Completed: 2 ms rowSize= 1.397 KB
  • CONCEPT_CHILDREN gt=2 ms Completed: 2 ms rowSize= 2.254 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 4.083 KB
  • CONCEPT_RELATIONSHIPS gt=41 ms Completed: 41 ms rowSize= 14.973 KB
  • CONCEPT_GENES gt=12 ms Completed: 12 ms rowSize= 22.950 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.146 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Peptic Ulcer C0030920
Definition (1)
A break in the lining of the lower part of the esophagus, the stomach, or the upper part of the small intestine. Peptic ulcers form when cells on the surface of the lining become inflamed and die. They are usually caused by Helicobacter pylori bacteria and by certain medicines, such as aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs). Peptic ulcers may be linked to cancer and other diseases.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (3)
img Duodenal Diseases C0013289
img Gastrointestinal Diseases C0017178
img Stomach Diseases C0038354
Children (5)
img Stomach Ulcer C0038358
img Esophagitis, Peptic C0014869
img Zollinger-Ellison Syndrome C0043515
img Duodenal Ulcer C0013295
img Peptic Ulcer Perforation C0030925
Ancestral Roots
RootRoot Plus OneDepthParent
img Digestive System Diseases C0012242img Gastrointestinal Diseases C00171785img Duodenal Diseases C0013289
img Digestive System Diseases C0012242img Gastrointestinal Diseases C00171783img Gastrointestinal Diseases C0017178
img Digestive System Diseases C0012242img Gastrointestinal Diseases C00171784img Stomach Diseases C0038354
Relationships (141)

Relation Types:
diso_​to_​anat : 9
diso_​to_​chem : 57
diso_​to_​diso : 72
diso_​to_​phen : 2
diso_​to_​phys : 1


Relationships:
none : 56
associated_​with : 2
classified_​as : 11
clinically_​similar : 15
is_​primary_​anatomic_​site_​of_​disease : 2
isa : 11
location_​of : 2
mapped_​to : 8
may_​treat : 29
related_​to : 4
use : 1
Page Size
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Prior Page
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Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO341img Helicobacter Infections C0079487
DISO_to_DISO226img Helicobacter Infections C0079487
DISO_to_CHEM185img Anti-Ulcer Agent C0003216
DISO_to_DISO166img chemically induced C0007994
DISO_to_DISO157img Complication Aspects C1171258
DISO_to_DISO140img chemically induced C0007994
DISO_to_CHEM126img 603-604 NON-STEROIDAL ANTI-INFLAMMATORY AGENTS C0003211
DISO_to_CHEM121img 603-604 NON-STEROIDAL ANTI-INFLAMMATORY AGENTS C0003211
DISO_to_DISO116img Complication Aspects C1171258
DISO_to_CHEM91img Anti-Ulcer Agent C0003216
DISO_to_CHEM69img Proton Pump Inhibitors C0358591
DISO_to_DISO69img Gastritis C0017152
DISO_to_CHEM68img 1H-Benzimidazole, 5-methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)- C0028978
DISO_to_CHEM68img Omeprazole C0028978
DISO_to_DISO61img BLEEDING GASTROINTESTINAL C0017181
DISO_to_CHEM59img Proton Pump C0018440
DISO_to_CHEM55img 2-(Acetyloxy)benzoic Acid C0004057
DISO_to_CHEM55img Aspirin C0004057
DISO_to_CHEM53img Anti-Bacterial Agents C0279516
DISO_to_DISO50img Stomach Neoplasms C0038356
DISO_to_DISO49img Bleeding peptic ulcer C0030922
DISO_to_DISO44img DYSPEPSIA C0013395
DISO_to_CHEM40img Anti-Bacterial Agents C0279516
DISO_to_DISO39img Stomach Neoplasms C0038356
DISO_to_DISO38img BLEEDING GASTROINTESTINAL C0017181
Genes (40)

Species:
human : 40
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanCISD2493856CDGSH iron sulfur domain 2
img GENERIF, Score=1000, Pubmed Id: 14724730, UMLKSK CUI: C0030920
HumanTREM154210triggering receptor expressed on myeloid cells 1
img GENERIF, Score=1000, Pubmed Id: 17729416, UMLKSK CUI: C0030920
HumanIL1F526525interleukin 36 receptor antagonist
INFERRED, Score=800, UMLKSK CUI: C0030920
HumanNOD110392nucleotide-binding oligomerization domain containing 1
img GENERIF, Score=1000, Pubmed Id: 17309748, UMLKSK CUI: C0030920
HumanXRCC17515X-ray repair complementing defective repair in Chinese hamster cells 1
INFERRED, Score=800, UMLKSK CUI: C0030920
HumanVEGFA7422vascular endothelial growth factor A
INFERRED, Score=800, UMLKSK CUI: C0030920
HumanTNF7124tumor necrosis factor
img GENERIF, Score=1000, Pubmed Id: 17667716, UMLKSK CUI: C0030920
img GENERIF, Score=983, Pubmed Id: 15978325, UMLKSK CUI: C0030920
HumanTLR27097toll-like receptor 2
INFERRED, Score=800, UMLKSK CUI: C0030920
HumanTGFB17040transforming growth factor, beta 1
img GENERIF, Score=1000, Pubmed Id: 17376051, UMLKSK CUI: C0030920
HumanCCL26347chemokine (C-C motif) ligand 2
INFERRED, Score=800, UMLKSK CUI: C0030920
HumanSCT6343secretin
img GENERIF, Score=1000, Pubmed Id: 18280672, UMLKSK CUI: C0030920
HumanPTGS25743prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
INFERRED, Score=800, UMLKSK CUI: C0030920
HumanPTGS15742prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
img GENERIF, Score=694, Pubmed Id: 17078001, UMLKSK CUI: C0030920
HumanPPARG5468peroxisome proliferator-activated receptor gamma
img GENERIF, Score=1000, Pubmed Id: 18372284, UMLKSK CUI: C0030920
HumanPLG5340plasminogen
INFERRED, Score=800, UMLKSK CUI: C0030920
HumanPLAT5327plasminogen activator, tissue
INFERRED, Score=800, UMLKSK CUI: C0030920
HumanPGC5225progastricsin (pepsinogen C)
INFERRED, Score=800, UMLKSK CUI: C0030920
HumanSERPINE15054serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
INFERRED, Score=800, UMLKSK CUI: C0030920
HumanOGG149688-oxoguanine DNA glycosylase
INFERRED, Score=800, UMLKSK CUI: C0030920
HumanNFE2L24780nuclear factor, erythroid 2-like 2
INFERRED, Score=800, UMLKSK CUI: C0030920
HumanLDHA3939lactate dehydrogenase A
img GENERIF, Score=1000, Pubmed Id: 12712614, UMLKSK CUI: C0030920
HumanITGAX3687integrin, alpha X (complement component 3 receptor 4 subunit)
INFERRED, Score=800, UMLKSK CUI: C0030920
HumanITGAM3684integrin, alpha M (complement component 3 receptor 3 subunit)
INFERRED, Score=800, UMLKSK CUI: C0030920
HumanITGAL3683integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
INFERRED, Score=800, UMLKSK CUI: C0030920
HumanIL12B3593interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
img GENERIF, Score=1000, Pubmed Id: 15620465, UMLKSK CUI: C0030920
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0030920Peptic Ulcer0self