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Details
Link-It Detail - Disease - Pancreatitis
Debug Stats
  • ### Total Build Time: 63 ms 54.401 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 322 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 1.756 KB
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 555 bytes
  • CONCEPT_CHILDREN gt=3 ms Completed: 3 ms rowSize= 1.843 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.511 KB
  • CONCEPT_RELATIONSHIPS gt=35 ms Completed: 35 ms rowSize= 14.436 KB
  • CONCEPT_GENES gt=21 ms Completed: 21 ms rowSize= 32.643 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.146 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Pancreatitis C0030305
Definition (1)

The pancreas is a large gland behind the stomach and close to the first part of the small intestine. It secretes digestive juices into the small intestine through a tube called the pancreatic duct. The pancreas also releases the hormones insulin and glucagon into the bloodstream.

Pancreatitis is inflammation of the pancreas. It happens when digestive enzymes start digesting the pancreas itself. Pancreatitis can be acute or chronic. Either form is serious and can lead to complications.

Acute pancreatitis occurs suddenly and usually goes away in a few days with treatment. It is often caused by gallstones. Common symptoms are severe pain in the upper abdomen, nausea, and vomiting. Treatment is usually a few days in the hospital for intravenous (IV) fluids, antibiotics, and medicines to relieve pain.

Chronic pancreatitis does not heal or improve. It gets worse over time and leads to permanent damage. The most common cause is heavy alcohol use. Other causes include cystic fibrosis and other inherited disorders, high levels of calcium or fats in the blood, some medicines, and autoimmune conditions. Symptoms include nausea, vomiting, weight loss, and oily stools. Treatment may also be a few days in the hospital for intravenous (IV) fluids, medicines to relieve pain, and nutritional support. After that, you may need to start taking enzymes and eat a special diet. It is also important to not smoke or drink alcohol.

NIH: National Institute of Diabetes, Digestive and Kidney Diseases

Semantic Types (1)
Disease or Syndrome (T047)
Parents (1)
img Pancreatic Diseases C0030286
Children (4)
img Pancreatitis, Chronic C0149521
img Pancreatitis, Alcoholic C0376670
img Pancreatitis, Acute Necrotizing C0267941
img Pancreatitis, Graft C2350449
Ancestral Roots
RootRoot Plus OneDepthParent
img Digestive System Diseases C0012242img Pancreatic Diseases C00302863img Pancreatic Diseases C0030286
Relationships (209)

Relation Types:
diso_​to_​anat : 27
diso_​to_​chem : 62
diso_​to_​diso : 108
diso_​to_​gene : 2
diso_​to_​phen : 2
diso_​to_​phys : 8


Relationships:
none : 180
associated_​with : 4
gene_​associated_​with_​disease : 2
is_​associated_​anatomic_​site_​of : 2
isa : 13
mapped_​to : 2
may_​treat : 5
related_​to : 1
Page Size
Current 25
  Page 1 of 9
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO744img Complication Aspects C1171258
DISO_to_DISO713img Complication Aspects C1171258
DISO_to_DISO481img chemically induced C0007994
DISO_to_DISO424img AUTOIMMUNE DIS C0004364
DISO_to_DISO400img chemically induced C0007994
DISO_to_ANAT330img In Blood C0005768
DISO_to_ANAT302img Pancreas C0030274
DISO_to_ANAT299img Pancreas C0030274
DISO_to_PHEN269img genetic aspects C0017399
DISO_to_ANAT246img In Blood C0005768
DISO_to_DISO191img Pancreatic Neoplasm C0030297
DISO_to_DISO186img AUTOIMMUNE DIS C0004364
DISO_to_PHEN171img genetic aspects C0017399
DISO_to_CHEM113img Immunoglobulin G C0020852
DISO_to_ANAT102img Pancreatic Ducts C0030288
DISO_to_ANAT94img Biliary calculi C0242216
DISO_to_ANAT94img Pancreatic Ducts C0030288
DISO_to_CHEM73img Trypsinogen C0041243
DISO_to_CHEM61img TRYPSIN C0041236
DISO_to_ANAT59img Biliary calculi C0242216
DISO_to_DISO58img Hypertriglyceridemia C0020557
DISO_to_PHYS58img Mutation C0026882
DISO_to_DISO57img PANCREAS, CYST, FALSE C0030299
DISO_to_DISO51img Cholelithiasis C0008350
DISO_to_DISO49img PANCREAS, CYST, FALSE C0030299
Genes (76)

Species:
human : 76
Page Size
Current 25
  Page 1 of 4
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanUGT1A754577UDP glucuronosyltransferase 1 family, polypeptide A7
img GENERIF, Score=1000, Pubmed Id: 16199544, UMLKSK CUI: C0030305
HumanC18orf829919chromosome 18 open reading frame 8
img GAD, Score=1000, Pubmed Id: 12139236, UMLKSK CUI: C0030305
HumanBSCL226580Berardinelli-Seip congenital lipodystrophy 2 (seipin)
img OMIM, Score=1000, UMLKSK CUI: C0030305
HumanCTRC11330chymotrypsin C (caldecrin)
img OMIM, Score=1000, UMLKSK CUI: C0030305
img GENERIF, Score=694, Pubmed Id: 18059268, UMLKSK CUI: C0030305
HumanAGPAT2105551-acylglycerol-3-phosphate O-acyltransferase 2
img OMIM, Score=1000, UMLKSK CUI: C0030305
HumanCRISP310321cysteine-rich secretory protein 3
INFERRED, Score=800, UMLKSK CUI: C0030305
HumanADIPOQ9370adiponectin, C1Q and collagen domain containing
INFERRED, Score=800, UMLKSK CUI: C0030305
HumanSLC7A79056solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
img OMIM, Score=1000, UMLKSK CUI: C0030305
HumanTNFRSF10A8797tumor necrosis factor receptor superfamily, member 10a
INFERRED, Score=800, UMLKSK CUI: C0030305
HumanTNFRSF10B8795tumor necrosis factor receptor superfamily, member 10b
INFERRED, Score=800, UMLKSK CUI: C0030305
HumanTNFRSF10C8794tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
INFERRED, Score=800, UMLKSK CUI: C0030305
HumanTNFRSF10D8793tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
INFERRED, Score=800, UMLKSK CUI: C0030305
HumanTNFSF108743tumor necrosis factor (ligand) superfamily, member 10
INFERRED, Score=800, UMLKSK CUI: C0030305
HumanST8SIA47903ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
img GENERIF, Score=694, Pubmed Id: 12227654, UMLKSK CUI: C0030305
HumanVEGFA7422vascular endothelial growth factor A
img GAD, Score=1000, Pubmed Id: 15917409, UMLKSK CUI: C0030305
HumanTNF7124tumor necrosis factor
img GAD, Score=1000, Pubmed Id: 15841043, UMLKSK CUI: C0030305
img GAD, Score=1000, Pubmed Id: 15066699, UMLKSK CUI: C0030305
img GAD, Score=1000, Pubmed Id: 15917409, UMLKSK CUI: C0030305
img GAD, Score=1000, Pubmed Id: 15714129, UMLKSK CUI: C0030305
HumanTGFB17040transforming growth factor, beta 1
img GAD, Score=1000, Pubmed Id: 15066699, UMLKSK CUI: C0030305
img GENERIF, Score=1000, Pubmed Id: 15316224, UMLKSK CUI: C0030305
img GAD, Score=1000, Pubmed Id: 15316224, UMLKSK CUI: C0030305
img GENERIF, Score=1000, Pubmed Id: 16552334, UMLKSK CUI: C0030305
img GAD, Score=1000, Pubmed Id: 15917409, UMLKSK CUI: C0030305
img GAD, Score=1000, Pubmed Id: 15841043, UMLKSK CUI: C0030305
HumanSPP16696secreted phosphoprotein 1
INFERRED, Score=800, UMLKSK CUI: C0030305
HumanSPINK16690serine peptidase inhibitor, Kazal type 1
Click here to display 32 evidence detail records.
HumanSOD26648superoxide dismutase 2, mitochondrial
img GAD, Score=1000, Pubmed Id: 15131792, UMLKSK CUI: C0030305
img GAD, Score=1000, Pubmed Id: 16047490, UMLKSK CUI: C0030305
HumanCCL26347chemokine (C-C motif) ligand 2
img GAD, Score=1000, Pubmed Id: 15880317, UMLKSK CUI: C0030305
HumanRELA5970v-rel avian reticuloendotheliosis viral oncogene homolog A
INFERRED, Score=800, UMLKSK CUI: C0030305
HumanPTGS25743prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
INFERRED, Score=800, UMLKSK CUI: C0030305
HumanPRSS35646protease, serine, 3
INFERRED, Score=800, UMLKSK CUI: C0030305
HumanPRSS15644protease, serine, 1 (trypsin 1)
Click here to display 17 evidence detail records.
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0030305Pancreatitis0self