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Details
Link-It Detail - Disease - Osteoporosis, Postmenopausal
Debug Stats
  • ### Total Build Time: 454 ms 40.155 KB
  • CONCEPT_NAME gt=5 ms Completed: 5 ms rowSize= 354 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 396 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=2 ms Completed: 2 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=7 ms Completed: 7 ms rowSize= 548 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=8 ms Completed: 8 ms rowSize= 1.497 KB
  • CONCEPT_RELATIONSHIPS gt=398 ms Completed: 398 ms rowSize= 14.199 KB
  • CONCEPT_GENES gt=31 ms Completed: 31 ms rowSize= 21.811 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.162 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Osteoporosis, Postmenopausal C0029458
Definition (1)
Metabolic disorder associated with fractures of the femoral neck, vertebrae, and distal forearm. It occurs commonly in women within 15-20 years after menopause, and is caused by factors associated with menopause including estrogen deficiency.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (1)
img Osteoporosis C0029456
Ancestral Roots
RootRoot Plus OneDepthParent
img Musculoskeletal Diseases C0026857img Bone Diseases C00059405img Osteoporosis C0029456
Relationships (265)

Relation Types:
diso_​to_​anat : 6
diso_​to_​chem : 230
diso_​to_​diso : 16
diso_​to_​phen : 2
diso_​to_​phys : 11


Relationships:
none : 60
clinically_​similar : 1
may_​prevent : 122
may_​treat : 80
permuted_​term_​of : 1
used_​for : 1
Page Size
Current 25
  Page 1 of 11
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_CHEM681img Bone Density Conservation Agents C1563726
DISO_to_DISO491img Complication Aspects C1171258
DISO_to_PHYS464img Bone Density C0005938
DISO_to_PHYS461img Bone Density C0005938
DISO_to_DISO432img Complication Aspects C1171258
DISO_to_CHEM252img Diphosphonates C0012544
DISO_to_DISO248img Fracture C0016658
DISO_to_ANAT197img In Blood C0005768
DISO_to_DISO176img Fracture C0016658
DISO_to_CHEM171img (4-Amino-1-hydroxybutylidene)bisphosphonic Acid C0102118
DISO_to_CHEM157img Bone Density Conservation Agents C1563726
DISO_to_CHEM144img Diphosphonates C0012544
DISO_to_DISO137img Spinal Fractures C0080179
DISO_to_CHEM129img (4-Amino-1-hydroxybutylidene)bisphosphonic Acid C0102118
DISO_to_CHEM123img Keoxifene C0244404
DISO_to_DISO117img Spinal Fractures C0080179
DISO_to_ANAT113img BONE BONES C0005931
DISO_to_CHEM113img (1-Hydroxyethylidene)bisphosphonic Acid C0015121
DISO_to_PHYS109img POST MENOPAUSE C0206159
DISO_to_CHEM107img Selective Estrogen Receptor Modulators C0732611
DISO_to_ANAT106img In Blood C0005768
DISO_to_PHEN101img genetic aspects C0017399
DISO_to_DISO96img Fractures, Spontaneous C0016663
DISO_to_DISO94img FRACTURE DUE TO OSTEOPOROSIS C0521170
DISO_to_ANAT92img BONE BONES C0005931
Genes (19)

Species:
human : 19
SpeciesGeneGeneIdGene NameEvidence
HumanBMND8100188854bone mineral density quantiative trait locus 8
img OMIM, Score=1000, UMLKSK CUI: C0029458
HumanBMND7100188853bone mineral density quantiative trait locus 7
img OMIM, Score=1000, UMLKSK CUI: C0029458
HumanIL1F627179interleukin 36, alpha
img GENERIF, Score=884, Pubmed Id: 12110411, UMLKSK CUI: C0029458
HumanTNFSF118600tumor necrosis factor (ligand) superfamily, member 11
img GENERIF, Score=1000, Pubmed Id: 12564836, UMLKSK CUI: C0029458
img GENERIF, Score=1000, Pubmed Id: 18502820, UMLKSK CUI: C0029458
HumanPDLIM48572PDZ and LIM domain 4
img OMIM, Score=1000, UMLKSK CUI: C0029458
HumanVDR7421vitamin D (1,25- dihydroxyvitamin D3) receptor
img GENERIF, Score=1000, Pubmed Id: 12673591, UMLKSK CUI: C0029458
img OMIM, Score=1000, UMLKSK CUI: C0029458
HumanTNFRSF11B4982tumor necrosis factor receptor superfamily, member 11b
img GENERIF, Score=1000, Pubmed Id: 12564836, UMLKSK CUI: C0029458
img GENERIF, Score=1000, Pubmed Id: 12213850, UMLKSK CUI: C0029458
HumanNPPB4879natriuretic peptide B
img GAD, Score=909, Pubmed Id: 12601551, UMLKSK CUI: C0029458
img GENERIF, Score=923, Pubmed Id: 12601551, UMLKSK CUI: C0029458
HumanLRP54041low density lipoprotein receptor-related protein 5
img OMIM, Score=1000, UMLKSK CUI: C0029458
HumanIL63569interleukin 6 (interferon, beta 2)
img OMIM, Score=1000, UMLKSK CUI: C0029458
HumanICAM13383intercellular adhesion molecule 1
img GENERIF, Score=1000, Pubmed Id: 17390085, UMLKSK CUI: C0029458
HumanHP3240haptoglobin
img GENERIF, Score=1000, Pubmed Id: 11565553, UMLKSK CUI: C0029458
HumanESR22100estrogen receptor 2 (ER beta)
img GENERIF, Score=1000, Pubmed Id: 12137804, UMLKSK CUI: C0029458
HumanESR12099estrogen receptor 1
img GENERIF, Score=1000, Pubmed Id: 14764789, UMLKSK CUI: C0029458
HumanCOL1A21278collagen, type I, alpha 2
img OMIM, Score=1000, UMLKSK CUI: C0029458
HumanCOL1A11277collagen, type I, alpha 1
img OMIM, Score=1000, UMLKSK CUI: C0029458
HumanCNR21269cannabinoid receptor 2 (macrophage)
img GENERIF, Score=1000, Pubmed Id: 17390085, UMLKSK CUI: C0029458
HumanCNR11268cannabinoid receptor 1 (brain)
img GENERIF, Score=734, Pubmed Id: 16204352, UMLKSK CUI: C0029458
HumanCALCR799calcitonin receptor
img OMIM, Score=1000, UMLKSK CUI: C0029458
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0029458Osteoporosis, Postmenopausal0self