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Details
Link-It Detail - Disease - Osteoarthritis
Debug Stats
  • ### Total Build Time: 1,104 ms 41.593 KB
  • CONCEPT_NAME gt=8 ms Completed: 8 ms rowSize= 326 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 478 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=2 ms Completed: 2 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=16 ms Completed: 16 ms rowSize= 981 bytes
  • CONCEPT_CHILDREN gt=13 ms Completed: 13 ms rowSize= 1.401 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 4.062 KB
  • CONCEPT_RELATIONSHIPS gt=1,009 ms Completed: 1.009 Seconds rowSize= 15.915 KB
  • CONCEPT_GENES gt=37 ms Completed: 37 ms rowSize= 17.112 KB
  • CONCEPT_XREFS gt=18 ms Completed: 18 ms rowSize= 1.148 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Osteoarthritis C0029408
Definition (1)
A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (2)
img Arthritis C0003864
img Rheumatic Diseases C0035435
Children (3)
img Osteoarthritis, Knee C0409959
img Osteoarthritis, Hip C0029410
img Osteoarthritis, Spine C2350242
Ancestral Roots
RootRoot Plus OneDepthParent
img Musculoskeletal Diseases C0026857img Joint Diseases C00224084img Arthritis C0003864
img Musculoskeletal Diseases C0026857img Rheumatic Diseases C00354353img Rheumatic Diseases C0035435
img Skin and Connective Tissue Diseases C0175166img Connective Tissue Diseases C00097824img Rheumatic Diseases C0035435
Relationships (421)

Relation Types:
diso_​to_​anat : 48
diso_​to_​chem : 231
diso_​to_​diso : 125
diso_​to_​gene : 1
diso_​to_​phen : 2
diso_​to_​phys : 14


Relationships:
none : 156
alias_​of : 1
associated_​with : 1
classified_​as : 41
clinically_​similar : 3
inheritance_​type_​of : 1
is_​associated_​anatomic_​site_​of : 1
is_​primary_​anatomic_​site_​of_​disease : 1
isa : 25
location_​of : 1
manifestation_​of : 6
mapped_​to : 3
may_​treat : 177
related_​to : 4
Page Size
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Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANAT420img Cartilage, Articular C0007303
DISO_to_DISO388img Complication Aspects C1171258
DISO_to_PHEN332img genetic aspects C0017399
DISO_to_ANAT298img Cartilage, Articular C0007303
DISO_to_DISO291img Arthritis, Rheumatoid C0003873
DISO_to_DISO272img Arthritis, Rheumatoid C0003873
DISO_to_DISO268img Complication Aspects C1171258
DISO_to_ANAT259img Chondrocytes C0225369
DISO_to_CHEM215img 603-604 NON-STEROIDAL ANTI-INFLAMMATORY AGENTS C0003211
DISO_to_PHEN205img genetic aspects C0017399
DISO_to_DISO186img Pain C0030193
DISO_to_ANAT174img Chondrocyte C0225369
DISO_to_CHEM162img Anti-Inflammatory Agents, Non-Steroidal C0003211
DISO_to_CHEM138img Cyclooxygenase Inhibitors C0085387
DISO_to_ANAT132img Joint structure of shoulder region C0037009
DISO_to_ANAT113img Ankle Joint C0003087
DISO_to_ANAT102img In Blood C0005768
DISO_to_ANAT99img Cartilage C0007301
DISO_to_DISO96img Dog Diseases C0012979
DISO_to_DISO96img Pain C0030193
DISO_to_DISO94img Temporomandibular Joint Disorders C0039494
DISO_to_ANAT93img Thumb C0040067
DISO_to_ANAT92img Carpometacarpal Joints C0224620
DISO_to_ANAT92img Hand joint structure C0459470
DISO_to_CHEM88img Hyaluronic Acid C0020196
Genes (29)

Species:
human : 29
Page Size
Current 25
  Page 1 of 2
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanPARD3B117583par-3 family cell polarity regulator beta
INFERRED, Score=800, UMLKSK CUI: C0029408
HumanASPN54829asporin
INFERRED, Score=800, UMLKSK CUI: C0029408
HumanLRCH123143leucine-rich repeats and calponin homology (CH) domain containing 1
INFERRED, Score=800, UMLKSK CUI: C0029408
HumanPRG410216proteoglycan 4
INFERRED, Score=800, UMLKSK CUI: C0029408
HumanKL9365klotho
INFERRED, Score=800, UMLKSK CUI: C0029408
HumanGDF58200growth differentiation factor 5
INFERRED, Score=800, UMLKSK CUI: C0029408
HumanXCL26846chemokine (C motif) ligand 2
INFERRED, Score=800, UMLKSK CUI: C0029408
HumanPON15444paraoxonase 1
INFERRED, Score=800, UMLKSK CUI: C0029408
HumanPLAU5328plasminogen activator, urokinase
INFERRED, Score=800, UMLKSK CUI: C0029408
HumanPITX15307paired-like homeodomain 1
INFERRED, Score=800, UMLKSK CUI: C0029408
HumanPEPD5184peptidase D
INFERRED, Score=800, UMLKSK CUI: C0029408
HumanSERPINE15054serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
INFERRED, Score=800, UMLKSK CUI: C0029408
HumanMMP94318matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
INFERRED, Score=800, UMLKSK CUI: C0029408
HumanMMP24313matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
INFERRED, Score=800, UMLKSK CUI: C0029408
HumanIL4R3566interleukin 4 receptor
INFERRED, Score=800, UMLKSK CUI: C0029408
HumanIL1RN3557interleukin 1 receptor antagonist
INFERRED, Score=800, UMLKSK CUI: C0029408
HumanIL1B3553interleukin 1, beta
INFERRED, Score=800, UMLKSK CUI: C0029408
HumanIL1A3552interleukin 1, alpha
INFERRED, Score=800, UMLKSK CUI: C0029408
HumanFRZB2487frizzled-related protein
INFERRED, Score=800, UMLKSK CUI: C0029408
HumanESR12099estrogen receptor 1
INFERRED, Score=800, UMLKSK CUI: C0029408
HumanLPAR11902lysophosphatidic acid receptor 1
INFERRED, Score=800, UMLKSK CUI: C0029408
HumanACE1636angiotensin I converting enzyme
INFERRED, Score=800, UMLKSK CUI: C0029408
HumanCOMP1311cartilage oligomeric matrix protein
INFERRED, Score=800, UMLKSK CUI: C0029408
HumanCOL9A31299collagen, type IX, alpha 3
INFERRED, Score=800, UMLKSK CUI: C0029408
HumanCOL9A21298collagen, type IX, alpha 2
INFERRED, Score=800, UMLKSK CUI: C0029408
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0029408Osteoarthritis0self