| Human | VEGFA | 7422 | vascular endothelial growth factor A | Increased microvascular density in penetrating gastric carcinomas has an intimate causal relationship to high VEGF expression |
| Human | TP53 | 7157 | tumor protein p53 | Inactivation of p53 may be associated with the appearance of central consolidation within pure ground-glass opacity (GGO) on HRCT which reflects invasive features and may be useful as a molecular marker |
| Human | TBXAS1 | 6916 | thromboxane A synthase 1 (platelet) | Thromboxane synthase mutations in an increased bone density disorder (Ghosal syndrome) |
| Human | PRODH | 5625 | proline dehydrogenase (oxidase) 1 | we found evidence for COMT and PRODH epistasis: in patients with a COMT Val allele (rs4680) and with one or two mutated PRODH alleles, we observed increased WM density in the left inferior frontal lobe |
| Human | TNFRSF11B | 4982 | tumor necrosis factor receptor superfamily, member 11b | Islands of increased skull bone density |
| Human | MMP9 | 4318 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | MMP-9 abnormal expression may play a role in the increased vessel density notoriously found in bone marrow of acute myeloid leukemia (AML) patients at diagnosis and thus it may be involved in the leukemogenic process and in myelodysplastic syndrome |
| Human | MAN2B1 | 4125 | mannosidase, alpha, class 2B, member 1 | Lenticular 'spoke-like' opacities |
| Human | TACSTD2 | 4070 | tumor-associated calcium signal transducer 2 | The Q118X mutation of the M1S1 gene can produce either a gelatinous drop-like region or band-shaped opacities |
| Human | LRP5 | 4041 | low density lipoprotein receptor-related protein 5 | Six novel missense mutations in this gene shown in various conditions with an increased bone density and bone diseases |
| Human | LAMP2 | 3920 | lysosomal-associated membrane protein 2 | Fine lamellar white opacities on slit lamp exam in carrier females |
| Human | FIGF | 2277 | c-fos induced growth factor (vascular endothelial growth factor D) | Findings indicate that VEGF-D expression and increased lymph vessel density may have an important role for lymph node metastasis in papillary thyroid carcinoma |
| Human | FGF2 | 2247 | fibroblast growth factor 2 (basic) | Expression of basic fibroblast growth factor (bFGF) was significantly associated with increased microvessel density in cutaneous melanomas |
| Human | FGA | 2243 | fibrinogen alpha chain | newly identified nonsense mutation G4731T gives rise to a new stop codon at Aalpha-Glu 467; plasma clots from the patients were composed of very thin fibers, with increased fibrin density and reduced pore size |
| Human | EGFR | 1956 | epidermal growth factor receptor | EGFR mutations were frequently found in lung adenocarcinoma with ground-glass opacity (GGO) on High-Resolution CT in this study |
| Human | EDNRA | 1909 | endothelin receptor type A | there is an increased microvessel density (MVD) in metastatic bone lesions from different primary tumors, and ETA and ET1 are upregulated in metastatic bone lesions |
| Human | EDN1 | 1906 | endothelin 1 | there is an increased microvessel density (MVD) in metastatic bone lesions from different primary tumors, and ETA and ET1 are upregulated in metastatic bone lesions |
| Human | DRD2 | 1813 | dopamine receptor D2 | Tourette subjects had increased densities of prefrontal D2 receptor protein, greater than 140% of their matched control, suggesting the presence of a prefrontal-dopaminergic abnormality in Tourette syndrome |
| Human | DLX3 | 1747 | distal-less homeobox 3 | Increased bone density, mild-moderate (skull, spine, long bones) |
| Human | AGTR1 | 185 | angiotensin II receptor, type 1 | biochemical mechanism by which the +1166 A/C polymorphism can lead to increased AT1R densities and possibly cardiovascular disease |
