Human | ZGLP1 | 100125288 | zinc finger, GATA-like protein 1 | The lack of pre- and post-meal differences in satiety promoting hormone glucagon-like peptide-1 makes it an unlikely contributor to binge eating in this group of obese women |
Human | CCR2 | 729230 | chemokine (C-C motif) receptor 2 | Role of CC chemokine receptor 2 in bone marrow cells in the recruitment of macrophages into obese adipose tissue |
Human | LOC648998 | 648998 | | Overweight and obese adults demonstrate increased vascular endothelial expression of NAD(P)H oxidase-p47(phox) linked to oxidative stress |
Human | OB4 | 404683 | Obesity, susceptibility to, on chromosome 4 | |
Human | OB10Q | 353126 | Obesity, susceptibility to, on chromosome 10q | |
Human | SNORD115-1 | 338433 | | INFERRED, Score=800, UMLKSK CUI: C0028754 |
Human | ANKK1 | 255239 | ankyrin repeat and kinase domain containing 1 | APM linkage analysis suggested that the DD2R gene TaqI polymorphism had evidence of linkage with blood pressure, as well as with obesity |
Human | CAQ14 | 171512 | Circulating adiponectin QTL on chromosome 14 | Low plasma levels predict the presence of liver steatosis in obese subjects |
Human | BBS12 | 166379 | Bardet-Biedl syndrome 12 | |
Human | CCDC80 | 151887 | coiled-coil domain containing 80 | In conclusion, the expression pattern of URB suggests its role in obesity and the results suggest that URB is secreted, at least in part, from adipocytes |
Human | PTPRVP | 148713 | protein tyrosine phosphatase, receptor type, V, pseudogene | Transgenic mice lacking protein tyrosine phosphatase OST-PTP are hypoglycemic and are protected from obesity and glucose intolerance because of an increase in islet beta-cell proliferation, insulin secretion, and insulin sensitivity |
Human | SERPINA12 | 145264 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 | Induction of human vaspin mRNA expression in adipose tissue is regulated in a fat depot-specific manner and could be associated with parameters of obesity, insulin resistance, and glucose metabolism |
Human | GPR119 | 139760 | G protein-coupled receptor 119 | GPR119 therefore represents a novel and attractive potential target for the therapy of obesity and related metabolic disorders |
Human | PPARGC1B | 133522 | peroxisome proliferator-activated receptor gamma, coactivator 1 beta | Recent studies have elucidated the function of the PGC-1 coactivators in different tissues and have highlighted the implications of PGC-1 dysregulation in diseases such as diabetes, obesity, cardiomyopathy, or neurodegeneration Variation of PGC-1beta may contribute to the pathogenesis of obesity, with a widespread Ala203 allele being a risk factor for the development of this common disorder |
Human | BBS5 | 129880 | Bardet-Biedl syndrome 5 | |
Human | NIPA1 | 123606 | non imprinted in Prader-Willi/Angelman syndrome 1 | INFERRED, Score=800, UMLKSK CUI: C0028754 |
Human | TTC8 | 123016 | tetratricopeptide repeat domain 8 | |
Human | APOA5 | 116519 | apolipoprotein A-V | Title:Further evidence for the association between obesity-related traits and the apolipoprotein A-IV gene.|Association:Y|Conclusion:Our data suggest that the APOA-IV gene polymorphisms investigated are associated with obesity-related traits. The effects of X*2 and 347Ser variants on BMI and the 360His variant on waist circumference depended on smoking status. The rare allele of each of 4 variants of APOA5 & the haplotype defined by presence of rare alleles in these 4 variants were each significantly associated with common carotid artery intimal medial thickness in obese participants the APOA5-1131T>C SNP, which is present in approximately 13% of this population, modulates the effect of fat intake on BMI and obesity risk in both men and women |
Human | TUBGCP5 | 114791 | tubulin, gamma complex associated protein 5 | INFERRED, Score=800, UMLKSK CUI: C0028754 |
Human | TMEM67 | 91147 | transmembrane protein 67 | |
Human | DGAT2 | 84649 | diacylglycerol O-acyltransferase 2 | our results do not support the hypothesis of an important role of common genetic variation in DGAT2 for the development of obesity |
Human | MCHR2 | 84539 | melanin-concentrating hormone receptor 2 | MCHR2 is not a major contributor to polygenic obesity |
Human | ARL6 | 84100 | ADP-ribosylation factor-like 6 | |
Human | USP26 | 83844 | ubiquitin specific peptidase 26 | |
Human | NIPA2 | 81614 | non imprinted in Prader-Willi/Angelman syndrome 2 | INFERRED, Score=800, UMLKSK CUI: C0028754 |