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Details
Link-It Detail - Disease - Neuritis, Autoimmune, Experimental
Debug Stats
  • ### Total Build Time: 20 ms 16.724 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 419 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 800 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 198 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=2 ms Completed: 2 ms rowSize= 1,009 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=5 ms Completed: 5 ms rowSize= 4.126 KB
  • CONCEPT_RELATIONSHIPS gt=7 ms Completed: 7 ms rowSize= 8.981 KB
  • CONCEPT_GENES gt=1 ms Completed: 1 ms rowSize= 45 bytes
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.168 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
Neuritis, Autoimmune, Experimental C0027814
ALLERGIC NEURITIS EXPER
Definition (1)
An experimental animal model for the demyelinating disease of GUILLAINE-BARRE SYNDROME. In the most frequently used protocol, animals are injected with a peripheral nerve tissue protein homogenate. After approximately 2 weeks the animals develop a neuropathy secondary to a T cell-mediated autoimmune response directed towards the MYELIN P2 PROTEIN in peripheral nerves. Pathologic findings include a perivascular accumulation of macrophages and T lymphocytes in the peripheral nervous system, similar to that seen in the Guillaine-Barre syndrome. (From Adams et al., Principles of Neurology, 6th ed, p1314; J Neuroimmunol 1998 Apr 1;84(1):40-52)
Semantic Types (1)
Experimental Model of Disease (T050)
Parents (2)
img Neuritis C0027813
img Nervous System Autoimmune Disease, Experimental C0752090
Ancestral Roots
RootRoot Plus OneDepthParent
img Nervous System Diseases C0027765img Neuromuscular Diseases C00278685img Neuritis C0027813
img Immune System Diseases C0021053img Autoimmune Diseases C00043645img Nervous System Autoimmune Disease, Experimental C0752090
img Nervous System Diseases C0027765img Autoimmune Diseases of the Nervous System C07518714img Nervous System Autoimmune Disease, Experimental C0752090
Relationships (22)

Relation Types:
diso_​to_​anat : 11
diso_​to_​chem : 3
diso_​to_​diso : 6
diso_​to_​phen : 2


Relationships:
none : 21
entry_​version_​of : 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_PHEN11img genetic aspects C0017399
DISO_to_ANAT10img Sciatic Nerve C0036394
DISO_to_DISO10img Guillain-Barre Syndrome C0018378
DISO_to_ANAT7img T-Lymphocyte C0039194
DISO_to_DISO7img chemically induced C0007994
DISO_to_ANAT6img Peripheral Nerves C0031119
DISO_to_ANAT6img Sciatic Nerve C0036394
DISO_to_ANAT5img Macrophages C0024432
DISO_to_CHEM5img Myelin P0 Protein C0071316
DISO_to_DISO5img chemically induced C0007994
DISO_to_PHEN5img genetic aspects C0017399
DISO_to_ANAT4img T-Lymphocyte C0039194
DISO_to_ANAT4img T-Lymphocyte Subsets C0080202
DISO_to_DISO4img Complication Aspects C1171258
DISO_to_ANAT3img CD4 Positive T Lymphocytes C0039215
DISO_to_ANAT3img Myelin Sheath C0026973
DISO_to_ANAT3img Schwann Cells C0036387
DISO_to_ANAT3img Spinal Cord C0037925
DISO_to_CHEM3img Adjuvants, Immunologic C0001551
DISO_to_CHEM3img Ganglioside C0017082
DISO_to_DISO3img Inflammation C0021368
DISO_to_DISOentry_version_ofimg ALLERGIC NEURITIS EXPER C0027814
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0027814Neuritis, Autoimmune, Experimental0self