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Details
Link-It Detail - Disease - Melanoma
Debug Stats
  • ### Total Build Time: 391 ms 63.207 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 314 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 771 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 993 bytes
  • CONCEPT_CHILDREN gt=2 ms Completed: 2 ms rowSize= 1.412 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 2.774 KB
  • CONCEPT_RELATIONSHIPS gt=165 ms Completed: 165 ms rowSize= 16.588 KB
  • CONCEPT_GENES gt=217 ms Completed: 217 ms rowSize= 39.051 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.143 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Melanoma C0025202
Definition (1)
A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
Semantic Types (1)
Neoplastic Process (T191)
Parents (2)
img Neuroendocrine Tumors C0206754
img Nevi and Melanomas C0206769
Children (3)
img Melanoma, Amelanotic C0206735
img Hutchinsons Melanotic Freckle C0149722
img Melanoma, Experimental C0025205
Ancestral Roots
RootRoot Plus OneDepthParent
img Neoplasms C0027651img Neoplasms by Histologic Type C00276526img Neuroendocrine Tumors C0206754
img Neoplasms C0027651img Neoplasms by Histologic Type C00276524img Nevi and Melanomas C0206769
Relationships (502)

Relation Types:
diso_​to_​anat : 37
diso_​to_​chem : 203
diso_​to_​diso : 189
diso_​to_​gene : 41
diso_​to_​phen : 6
diso_​to_​phys : 26


Relationships:
none : 298
associated_​with : 42
clinically_​similar : 1
disease_​has_​associated_​disease : 1
gene_​associated_​with_​disease : 36
gene_​product_​is_​biomarker_​of : 1
gene_​product_​malfunction_​associated_​with_​disease : 9
is_​abnormal_​cell_​of_​disease : 3
is_​normal_​cell_​origin_​of_​disease : 1
is_​normal_​tissue_​origin_​of_​disease : 1
isa : 32
mapped_​to : 3
may_​be_​finding_​of_​disease : 2
may_​treat : 69
permuted_​term_​of : 1
related_​to : 2
Page Size
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Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO5230img Cutaneous tumor C0037286
DISO_to_DISO3899img Cutaneous tumor C0037286
DISO_to_PHEN1819img genetic aspects C0017399
DISO_to_PHEN1169img genetic aspects C0017399
DISO_to_CHEM644img Antineoplastic Agents C0003392
DISO_to_DISO488img Neoplasm of Uvea C0042162
DISO_to_DISO445img Neoplasm of Uvea C0042162
DISO_to_CHEM386img Antineoplastic Agents C0003392
DISO_to_CHEM363img BIOCHEM TUMOR MARKERS C0041366
DISO_to_CHEM298img NEOPL PROTEINS C0027642
DISO_to_PHYS298img GENE EXPRESSION REG NEOPL C0017268
DISO_to_DISO295img Choroid Neoplasms C0008523
DISO_to_CHEM291img Antineoplastic Vaccine C0376659
DISO_to_PHYS273img Apoptosis C0162638
DISO_to_ANAT270img Lymph Nodes C0024204
DISO_to_DISO262img Complication Aspects C1171258
DISO_to_DISO258img CHOROID NEOPL C0008523
DISO_to_CHEM256img B raf Kinases C0104940
DISO_to_DISO253img Melanocytic nevus C0027962
DISO_to_DISO240img Melanocytic nevus C0027962
DISO_to_CHEM238img NEOPL PROTEINS C0027642
DISO_to_CHEM237img BIOCHEM TUMOR MARKERS C0041366
DISO_to_ANAT231img In Blood C0005768
DISO_to_CHEM226img Antibodies, Monoclonal C0003250
DISO_to_ANAT222img Melanocytes C0025201
Genes (1079)

Species:
human : 991
mouse : 88
Page Size
Current 25
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Prior Page
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SpeciesGeneGeneIdGene NameEvidence
MouseLAMA1284217laminin, alpha 1
img NCI, Score=801, Pubmed Id: 10366438, UMLKSK CUI: C0025202
MouseDCD117159dermcidin
img NCI, Score=801, Pubmed Id: 10468289, UMLKSK CUI: C0025202
MouseJAM383700junctional adhesion molecule 3
img NCI, Score=801, Pubmed Id: 17227766, UMLKSK CUI: C0025202
MouseAKR1B1057016aldo-keto reductase family 1, member B10 (aldose reductase)
img NCI, Score=801, Pubmed Id: 10628359, UMLKSK CUI: C0025202
MouseENAH55740enabled homolog (Drosophila)
img NCI, Score=801, Pubmed Id: 10725224, UMLKSK CUI: C0025202
MouseBANP54971BTG3 associated nuclear protein
img NCI, Score=801, Pubmed Id: 12494467, UMLKSK CUI: C0025202
MouseCASZ154897castor zinc finger 1
img NCI, Score=801, Pubmed Id: 16322216, UMLKSK CUI: C0025202
img NCI, Score=801, Pubmed Id: 16322216, UMLKSK CUI: C0025202
MouseEPB41L4B54566erythrocyte membrane protein band 4.1 like 4B
img NCI, Score=801, Pubmed Id: 10783258, UMLKSK CUI: C0025202
img NCI, Score=801, Pubmed Id: 10783258, UMLKSK CUI: C0025202
MouseCD24451744CD244 molecule, natural killer cell receptor 2B4
img NCI, Score=801, Pubmed Id: 14666660, UMLKSK CUI: C0025202
img NCI, Score=801, Pubmed Id: 15634901, UMLKSK CUI: C0025202
MouseCCRL151554
img NCI, Score=801, Pubmed Id: 14581607, UMLKSK CUI: C0025202
img NCI, Score=801, Pubmed Id: 14581607, UMLKSK CUI: C0025202
MouseHSPH110808heat shock 105kDa/110kDa protein 1
img NCI, Score=801, Pubmed Id: 16232202, UMLKSK CUI: C0025202
MousePOSTN10631periostin, osteoblast specific factor
img NCI, Score=801, Pubmed Id: 15880581, UMLKSK CUI: C0025202
MouseTXNIP10628thioredoxin interacting protein
Click here to display 3 evidence detail records.
MouseHTATIP210553HIV-1 Tat interactive protein 2, 30kDa
img NCI, Score=801, Pubmed Id: 11313954, UMLKSK CUI: C0025202
MouseS1PR29294sphingosine-1-phosphate receptor 2
img NCI, Score=801, Pubmed Id: 12803545, UMLKSK CUI: C0025202
img NCI, Score=801, Pubmed Id: 12803545, UMLKSK CUI: C0025202
MouseTMSB109168thymosin beta 10
img NCI, Score=801, Pubmed Id: 8425765, UMLKSK CUI: C0025202
MouseHGS9146hepatocyte growth factor-regulated tyrosine kinase substrate
img NCI, Score=801, Pubmed Id: 7565774, UMLKSK CUI: C0025202
MouseWASF18936WAS protein family, member 1
img NCI, Score=801, Pubmed Id: 15608687, UMLKSK CUI: C0025202
MouseWISP18840WNT1 inducible signaling pathway protein 1
img NCI, Score=801, Pubmed Id: 12865923, UMLKSK CUI: C0025202
MouseTNFRSF11A8792tumor necrosis factor receptor superfamily, member 11a, NFKB activator
img NCI, Score=801, Pubmed Id: 17314931, UMLKSK CUI: C0025202
MouseMAD1L18379MAD1 mitotic arrest deficient-like 1 (yeast)
img NCI, Score=801, Pubmed Id: 12366697, UMLKSK CUI: C0025202
MousePLA2G77941phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
img NCI, Score=801, Pubmed Id: 14519648, UMLKSK CUI: C0025202
MouseCXCR47852chemokine (C-X-C motif) receptor 4
Click here to display 5 evidence detail records.
MouseVTNR7449
img NCI, Score=801, Pubmed Id: 9417058, UMLKSK CUI: C0025202
MouseVCL7414vinculin
img NCI, Score=801, Pubmed Id: 10725224, UMLKSK CUI: C0025202
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0025202Melanoma0self