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Details
Link-It Detail - Disease - Malaria
Debug Stats
  • ### Total Build Time: 297 ms 51.563 KB
  • CONCEPT_NAME gt=18 ms Completed: 18 ms rowSize= 312 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 651 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=5 ms Completed: 5 ms rowSize= 556 bytes
  • CONCEPT_CHILDREN gt=5 ms Completed: 5 ms rowSize= 1.813 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=4 ms Completed: 4 ms rowSize= 1.506 KB
  • CONCEPT_RELATIONSHIPS gt=233 ms Completed: 233 ms rowSize= 14.673 KB
  • CONCEPT_GENES gt=26 ms Completed: 26 ms rowSize= 30.735 KB
  • CONCEPT_XREFS gt=4 ms Completed: 4 ms rowSize= 1.142 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Malaria C0024530
Definition (1)
protozoan disease caused in humans by four species of the genus Plasmodium (P. falciparum, P. vivax, P. ovale, and P. malariae) and transmitted by the bite of an infected female mosquito of the genus Anopheles; malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands; characterized by extreme exhaustion associated with paroxysms of high fever, sweating, shaking chills, and anemia; malaria in animals is caused by other species of plasmodia.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (1)
img Protozoan Infections C0033740
Children (4)
img Malaria, Avian C0024533
img Malaria, Falciparum C0024535
img Malaria, Vivax C0024537
img Malaria, Cerebral C0024534
Ancestral Roots
RootRoot Plus OneDepthParent
img Parasitic Diseases C0030499img Protozoan Infections C00337403img Protozoan Infections C0033740
Relationships (227)

Relation Types:
diso_​to_​anat : 16
diso_​to_​chem : 102
diso_​to_​diso : 82
diso_​to_​gene : 3
diso_​to_​phen : 16
diso_​to_​phys : 8


Relationships:
none : 134
classifies : 1
clinically_​similar : 22
gene_​associated_​with_​disease : 2
isa : 20
mapped_​to : 5
may_​prevent : 34
may_​treat : 7
related_​to : 2
Page Size
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  Page 1 of 10
Prior Page
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Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_CHEM990img 565 ANTIMALARIAL AGENTS C0003374
DISO_to_CHEM547img 565 ANTIMALARIAL AGENTS C0003374
DISO_to_DISO348img Complication Aspects C1171258
DISO_to_CHEM274img Artemisinins C1136174
DISO_to_CHEM261img Malaria Vaccines C0206255
DISO_to_ANAT237img In Blood C0005768
DISO_to_DISO214img Complication Aspects C1171258
DISO_to_ANAT198img In Blood C0005768
DISO_to_CHEM176img Insecticides C0021576
DISO_to_PHEN163img genetic aspects C0017399
DISO_to_DISO162img Pregnancy Complications, Parasitic C0162494
DISO_to_CHEM149img Malaria Vaccines C0206255
DISO_to_CHEM136img 231-232 INSECTICIDES C0021576
DISO_to_DISO125img Parasitemia C0242723
DISO_to_CHEM121img Proteins, Protozoan C0033742
DISO_to_ANAT107img Erythrocytes C0014792
DISO_to_DISO104img HIV Infections C0019693
DISO_to_DISO100img Anemia C0002871
DISO_to_PHEN99img genetic aspects C0017399
DISO_to_CHEM92img 2,4-Pyrimidinediamine, 5-(4-chlorophenyl)-6-ethyl- C0034283
DISO_to_CHEM89img Artemisinins C1136174
DISO_to_CHEM88img Antigens, Protozoan C0003338
DISO_to_CHEM88img Benzenesulfonamide, 4-amino-N-(5,6-dimethoxy-4-pyrimidinyl)- C0038679
DISO_to_DISO87img Disease, Endemic C0277550
DISO_to_DISO77img Fever C0015967
Genes (77)

Species:
human : 77
Page Size
Current 25
  Page 1 of 4
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanNCF1653361neutrophil cytosolic factor 1
INFERRED, Score=800, UMLKSK CUI: C0024530
HumanNCR3259197natural cytotoxicity triggering receptor 3
img GENERIF, Score=861, Pubmed Id: 17208487, UMLKSK CUI: C0024530
HumanSPPL3121665signal peptide peptidase like 3
img GENERIF, Score=694, Pubmed Id: 16873890, UMLKSK CUI: C0024530
HumanCOL18A180781collagen, type XVIII, alpha 1
INFERRED, Score=800, UMLKSK CUI: C0024530
HumanIL2159067interleukin 21
INFERRED, Score=800, UMLKSK CUI: C0024530
HumanHAMP57817hepcidin antimicrobial peptide
img GENERIF, Score=694, Pubmed Id: 17766053, UMLKSK CUI: C0024530
HumanTLR954106toll-like receptor 9
img GENERIF, Score=861, Pubmed Id: 17854755, UMLKSK CUI: C0024530
HumanIL23A51561interleukin 23, alpha subunit p19
img GENERIF, Score=861, Pubmed Id: 17945537, UMLKSK CUI: C0024530
HumanHAVCR126762hepatitis A virus cellular receptor 1
INFERRED, Score=800, UMLKSK CUI: C0024530
HumanVNN18876vanin 1
img GENERIF, Score=1000, Pubmed Id: 17312006, UMLKSK CUI: C0024530
HumanBAT27916
img GENERIF, Score=861, Pubmed Id: 19039607, UMLKSK CUI: C0024530
HumanVEGFA7422vascular endothelial growth factor A
INFERRED, Score=800, UMLKSK CUI: C0024530
HumanTNFAIP17126tumor necrosis factor, alpha-induced protein 1 (endothelial)
img GAD, Score=666, Pubmed Id: 11929592, UMLKSK CUI: C0024530
HumanTNF7124tumor necrosis factor
Click here to display 10 evidence detail records.
HumanTLR47099toll-like receptor 4
img GENERIF, Score=1000, Pubmed Id: 17373355, UMLKSK CUI: C0024530
img GENERIF, Score=694, Pubmed Id: 19048480, UMLKSK CUI: C0024530
img GAD, Score=1000, Pubmed Id: 16371473, UMLKSK CUI: C0024530
img GENERIF, Score=1000, Pubmed Id: 16371473, UMLKSK CUI: C0024530
HumanTLR27097toll-like receptor 2
img GAD, Score=1000, Pubmed Id: 16371473, UMLKSK CUI: C0024530
HumanTCN26948transcobalamin II
img GENERIF, Score=1000, Pubmed Id: 17220211, UMLKSK CUI: C0024530
HumanSPTA16708spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
img GENERIF, Score=694, Pubmed Id: 17414207, UMLKSK CUI: C0024530
HumanSLC4A16521solute carrier family 4 (anion exchanger), member 1
img GENERIF, Score=861, Pubmed Id: 16960783, UMLKSK CUI: C0024530
img GENERIF, Score=694, Pubmed Id: 15500919, UMLKSK CUI: C0024530
img GENERIF, Score=660, Pubmed Id: 15478802, UMLKSK CUI: C0024530
HumanSELE6401selectin E
img GAD, Score=1000, Pubmed Id: 16002039, UMLKSK CUI: C0024530
HumanCX3CL16376chemokine (C-X3-C motif) ligand 1
INFERRED, Score=800, UMLKSK CUI: C0024530
HumanCCL186362chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
img GENERIF, Score=1000, Pubmed Id: 12626578, UMLKSK CUI: C0024530
HumanPKLR5313pyruvate kinase, liver and RBC
img GENERIF, Score=1000, Pubmed Id: 18460648, UMLKSK CUI: C0024530
img GENERIF, Score=1000, Pubmed Id: 18420493, UMLKSK CUI: C0024530
HumanPECAM15175platelet/endothelial cell adhesion molecule 1
img GAD, Score=1000, Pubmed Id: 16002039, UMLKSK CUI: C0024530
img GAD, Score=1000, Pubmed Id: 11719109, UMLKSK CUI: C0024530
HumanNOS24843nitric oxide synthase 2, inducible
Click here to display 9 evidence detail records.
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0024530Malaria0self