Debug Stats | ### Total Build Time: 147 ms 50.100 KB CONCEPT_NAME gt=15 ms Completed: 15 ms rowSize= 340 bytesCONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytesCONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 475 bytes- Skipping details on:
CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes - Skipping details on:
CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 187 bytes- Skipping details on:
CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 544 bytesCONCEPT_CHILDREN gt=3 ms Completed: 3 ms rowSize= 3.130 KBCONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 4.034 KBCONCEPT_RELATIONSHIPS gt=60 ms Completed: 60 ms rowSize= 16.554 KBCONCEPT_GENES gt=66 ms Completed: 66 ms rowSize= 23.689 KBCONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.155 KBCONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes- Reload Stats
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Relationships (379)
Relation Types: diso_to_anat : 25 diso_to_chem : 87 diso_to_diso : 240 diso_to_gene : 17 diso_to_phen : 2 diso_to_phys : 8
Relationships: none : 161 classified_as : 83 gene_associated_with_disease : 16 gene_product_malfunction_associated_with_disease : 4 is_abnormal_cell_of_disease : 4 is_associated_anatomic_site_of : 1 is_normal_cell_origin_of_disease : 2 is_normal_tissue_origin_of_disease : 2 is_not_abnormal_cell_of_disease : 1 is_not_normal_cell_origin_of_disease : 2 is_primary_anatomic_site_of_disease : 1 isa : 60 mapped_to : 2 may_treat : 39 permuted_term_of : 1 | |
DISO_to_DISO | 374 | |
Complication Aspects C1171258 | DISO_to_DISO | 305 | |
Complication Aspects C1171258 | DISO_to_CHEM | 296 | |
Antibodies, Monoclonal C0003250 | DISO_to_PHEN | 286 | |
genetic aspects C0017399 | DISO_to_PHEN | 264 | |
genetic aspects C0017399 | DISO_to_DISO | 234 | |
Hodgkin Disease C0019829 | DISO_to_CHEM | 208 | |
Antineoplastic Agents C0003392 | DISO_to_DISO | 201 | |
Hodgkin Disease C0019829 | DISO_to_CHEM | 200 | |
Antibodies, Monoclonal C0003250 | DISO_to_CHEM | 185 | |
Antineoplastic Agents C0003392 | DISO_to_DISO | 166 | |
B-Cell Lymphomas C0079731 | DISO_to_ANAT | 113 | |
In Blood C0005768 | DISO_to_ANAT | 100 | |
In Blood C0005768 | DISO_to_CHEM | 88 | |
Cyclophosphamide C0010583 | DISO_to_DISO | 76 | |
Central Nervous System Neoplasms C0085136 | DISO_to_CHEM | 75 | |
Fluorodeoxyglucose F18 C0046056 | DISO_to_CHEM | 71 | |
Doxorubicin C0013089 | DISO_to_DISO | 71 | |
AIDS ASSOC LYMPHOMA C0085090 | DISO_to_DISO | 70 | |
Multiple Myeloma C0026764 | DISO_to_DISO | 65 | |
B-Cell Lymphomas C0079731 | DISO_to_DISO | 65 | |
chemically induced C0007994 | DISO_to_DISO | 63 | |
Chronic Lymphocytic Leukemia C0023434 | DISO_to_CHEM | 61 | |
Vincristine C0042679 | DISO_to_DISO | 61 | |
Central Nervous System Neoplasms C0085136 | DISO_to_CHEM | 60 | |
Fluorodeoxyglucose F18 C0046056 |
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Genes (713)
Species: human : 712 mouse : 1 | |
Mouse | IL1A | 3552 | interleukin 1, alpha | Antitumor activity of recombinant human interleukin 1 alpha (IL-1) against seven human non-Hodgkin lymphomas grown in athymic nude mice was studied. | Human | CTAGE4 | 100128553 | CTAGE family, member 4 | INFERRED, Score=800, UMLKSK CUI: C0024305 | Human | GGT2 | 728441 | gamma-glutamyltransferase 2 | There was no GGT expression in mesotheliomas, Hodgkins disease, non-Hodgkins lymphomas, melanomas, basal cell carcinomas, and most soft tissue sarcomas, all of which are derived from GGT-negative cells. A raised GGT in Hodgkins disease and non-Hodgkin lymphoma is generally associated with active and widespread disease, but not necessarily a sign of malignant tissue in the liver. | Human | LOC644165 | 644165 | | INFERRED, Score=800, UMLKSK CUI: C0024305 | Human | ERVK7 | 449619 | | Interestingly, all solid tissues containing high percentages of malignant cells such as breast cancer, colon carcinoma, low and high grade non-Hodgkin;s lymphomas showed exclusively HERV-K env related transcripts with low homology to HERV-K 10. | Human | MIR17HG | 407975 | miR-17-92 cluster host gene (non-protein coding) | INFERRED, Score=800, UMLKSK CUI: C0024305 | Human | MIR17 | 406952 | microRNA 17 | INFERRED, Score=800, UMLKSK CUI: C0024305 | Human | FLJ42953 | 400892 | | INFERRED, Score=800, UMLKSK CUI: C0024305 | Human | BLACE | 338436 | B-cell acute lymphoblastic leukemia expressed | INFERRED, Score=800, UMLKSK CUI: C0024305 | Human | SERPINA9 | 327657 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9 | INFERRED, Score=800, UMLKSK CUI: C0024305 | Human | MAGEA2B | 266740 | melanoma antigen family A, 2B | Of 7 non-Hodgkin;s lymphomas, one case from the oropharynx and 2 from the nasopharynx expressed for the MAGE-1 and MAGE-2 genes, respectively. | Human | GCET2 | 257144 | | INFERRED, Score=800, UMLKSK CUI: C0024305 | Human | NKAIN2 | 154215 | Na+/K+ transporting ATPase interacting 2 | INFERRED, Score=800, UMLKSK CUI: C0024305 | Human | PASD1 | 139135 | PAS domain containing 1 | INFERRED, Score=800, UMLKSK CUI: C0024305 | Human | SPACA3 | 124912 | sperm acrosome associated 3 | INFERRED, Score=800, UMLKSK CUI: C0024305 | Human | HIST4H4 | 121504 | histone cluster 4, H4 | Characterization of t(3;6)(q27;p21) breakpoints in B-cell non-Hodgkin;s lymphoma and construction of the histone H4/BCL6 fusion gene, leading to altered expression of Bcl-6. A recurrent translocation, t(3;6)(q27;p21), in non-Hodgkin;s lymphoma results in fusion of BCL6 with a particular histone H4 gene on 6p21. | Human | TNFRSF13C | 115650 | tumor necrosis factor receptor superfamily, member 13C | INFERRED, Score=800, UMLKSK CUI: C0024305 | Human | MIR155HG | 114614 | MIR155 host gene (non-protein coding) | INFERRED, Score=800, UMLKSK CUI: C0024305 | Human | TMEM54 | 113452 | transmembrane protein 54 | Via a 14;18 chromosomal translocation, BCLP is overexpressed in most follicular lymphomas as well as some other non-Hodgkins lymphomas, and it has also been documented in other nonlymphomatous malignancies. | Human | MUC16 | 94025 | mucin 16, cell surface associated | CA125 is expressed in patients with non-Hodgkin's lymphoma but appears not to be secreted by lymphoma cells directly | Human | ZNF804A | 91752 | zinc finger protein 804A | INFERRED, Score=800, UMLKSK CUI: C0024305 | Human | NAV3 | 89795 | neuron navigator 3 | INFERRED, Score=800, UMLKSK CUI: C0024305 | Human | MUM1 | 84939 | melanoma associated antigen (mutated) 1 | INFERRED, Score=800, UMLKSK CUI: C0024305 | Human | FCRLA | 84824 | Fc receptor-like A | INFERRED, Score=800, UMLKSK CUI: C0024305 | Human | TUBA1C | 84790 | tubulin, alpha 1c | INFERRED, Score=800, UMLKSK CUI: C0024305 |
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