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Details
Link-It Detail - Disease - Lupus Nephritis
Debug Stats
  • ### Total Build Time: 70 ms 58.427 KB
  • CONCEPT_NAME gt=10 ms Completed: 10 ms rowSize= 328 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 608 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 1,001 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=4 ms Completed: 4 ms rowSize= 5.404 KB
  • CONCEPT_RELATIONSHIPS gt=33 ms Completed: 33 ms rowSize= 14.298 KB
  • CONCEPT_GENES gt=17 ms Completed: 17 ms rowSize= 35.465 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.149 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Lupus Nephritis C0024143
Definition (1)
Glomerulonephritis associated with autoimmune disease SYSTEMIC LUPUS ERYTHEMATOSUS. Lupus nephritis is histologically classified into 6 classes: class I - normal glomeruli, class II - pure mesangial alterations, class III - focal segmental glomerulonephritis, class IV - diffuse glomerulonephritis, class V - diffuse membranous glomerulonephritis, and class VI - advanced sclerosing glomerulonephritis (The World Health Organization classification 1982).
Semantic Types (1)
Disease or Syndrome (T047)
Parents (2)
img Glomerulonephritis C0017658
img Lupus Erythematosus, Systemic C0024141
Ancestral Roots
RootRoot Plus OneDepthParent
img Female Urogenital Diseases and Pregnancy Complications C1720765img Female Urogenital Diseases C17208877img Glomerulonephritis C0017658
img Male Urogenital Diseases C1720894img Urologic Diseases C00420756img Glomerulonephritis C0017658
img Immune System Diseases C0021053img Autoimmune Diseases C00043644img Lupus Erythematosus, Systemic C0024141
img Skin and Connective Tissue Diseases C0175166img Connective Tissue Diseases C00097824img Lupus Erythematosus, Systemic C0024141
Relationships (78)

Relation Types:
diso_​to_​anat : 15
diso_​to_​chem : 31
diso_​to_​diso : 23
diso_​to_​gene : 3
diso_​to_​phen : 2
diso_​to_​phys : 4


Relationships:
none : 59
associated_​with : 3
clinically_​similar : 4
gene_​associated_​with_​disease : 2
is_​associated_​anatomic_​site_​of : 2
isa : 2
location_​of : 1
may_​treat : 4
permuted_​term_​of : 1
Page Size
Current 25
  Page 1 of 4
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_CHEM175img Immunosuppressive Agents C0021081
DISO_to_DISO164img Complication Aspects C1171258
DISO_to_DISO160img Lupus Erythematosus, Systemic C0024141
DISO_to_CHEM124img Immunosuppressive Agents C0021081
DISO_to_PHEN113img genetic aspects C0017399
DISO_to_ANAT108img In Blood C0005768
DISO_to_ANAT102img Kidney C0022646
DISO_to_DISO99img Complication Aspects C1171258
DISO_to_CHEM88img Mycophenolic Acid C0026933
DISO_to_PHEN88img genetic aspects C0017399
DISO_to_DISO77img Lupus Erythematosus, Systemic C0024141
DISO_to_CHEM70img Cyclophosphamide C0010583
DISO_to_CHEM68img Cyclophosphamide C0010583
DISO_to_CHEM60img Abs - Autoantibodies C0004358
DISO_to_CHEM51img Mycophenolic Acid C0026933
DISO_to_ANAT49img In Blood C0005768
DISO_to_ANAT45img Kidney Glomerulus C0022663
DISO_to_CHEM44img Abs - Autoantibodies C0004358
DISO_to_DISO41img Kidney Failure, Chronic C0022661
DISO_to_DISO37img Proteinuria C0033687
DISO_to_ANAT31img Kidney C0022646
DISO_to_CHEM28img Antibodies, Antinuclear C0003243
DISO_to_ANAT25img Kidney Glomerulus C0022663
DISO_to_CHEM24img Antibodies, Antinuclear C0003243
DISO_to_CHEM24img Antibodies, Monoclonal C0003250
Genes (27)

Species:
human : 27
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanNEWENTRY192343Record to support submission of GeneRIFs for a gene not in Gene (human; man).
img GENERIF, Score=694, Pubmed Id: 18668574, UMLKSK CUI: C0024143
img GENERIF, Score=673, Pubmed Id: 17971360, UMLKSK CUI: C0024143
HumanTLR954106toll-like receptor 9
img GENERIF, Score=901, Pubmed Id: 17469139, UMLKSK CUI: C0024143
HumanIL2050604interleukin 20
img GENERIF, Score=1000, Pubmed Id: 18771958, UMLKSK CUI: C0024143
HumanANKRD127063ankyrin repeat domain 1 (cardiac muscle)
img GENERIF, Score=1000, Pubmed Id: 17239933, UMLKSK CUI: C0024143
HumanICOSLG23308inducible T-cell co-stimulator ligand
img GENERIF, Score=1000, Pubmed Id: 12960306, UMLKSK CUI: C0024143
HumanSELE6401selectin E
img GENERIF, Score=1000, Pubmed Id: 15086468, UMLKSK CUI: C0024143
HumanCCL56352chemokine (C-C motif) ligand 5
img GENERIF, Score=734, Pubmed Id: 17585540, UMLKSK CUI: C0024143
HumanCCL26347chemokine (C-C motif) ligand 2
img GENERIF, Score=901, Pubmed Id: 15188361, UMLKSK CUI: C0024143
HumanRARRES35920retinoic acid receptor responder (tazarotene induced) 3
img GENERIF, Score=734, Pubmed Id: 17403696, UMLKSK CUI: C0024143
HumanPTGS25743prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
img GENERIF, Score=694, Pubmed Id: 18459455, UMLKSK CUI: C0024143
HumanPDCD15133programmed cell death 1
img GENERIF, Score=901, Pubmed Id: 17228327, UMLKSK CUI: C0024143
img GENERIF, Score=1000, Pubmed Id: 14730631, UMLKSK CUI: C0024143
HumanSERPINE15054serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
img GAD, Score=1000, Pubmed Id: 11260416, UMLKSK CUI: C0024143
img GENERIF, Score=1000, Pubmed Id: 17469143, UMLKSK CUI: C0024143
HumanNOS34846nitric oxide synthase 3 (endothelial cell)
img GENERIF, Score=1000, Pubmed Id: 15338496, UMLKSK CUI: C0024143
HumanNOS14842nitric oxide synthase 1 (neuronal)
img GENERIF, Score=1000, Pubmed Id: 15119548, UMLKSK CUI: C0024143
HumanMPO4353myeloperoxidase
img GENERIF, Score=901, Pubmed Id: 17896805, UMLKSK CUI: C0024143
HumanIL183606interleukin 18 (interferon-gamma-inducing factor)
img GENERIF, Score=901, Pubmed Id: 18163476, UMLKSK CUI: C0024143
img GENERIF, Score=1000, Pubmed Id: 12390326, UMLKSK CUI: C0024143
HumanIL103586interleukin 10
img GENERIF, Score=1000, Pubmed Id: 16396704, UMLKSK CUI: C0024143
HumanICAM13383intercellular adhesion molecule 1
img GENERIF, Score=1000, Pubmed Id: 17340048, UMLKSK CUI: C0024143
HumanFCGR3A2214Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
img GAD, Score=1000, Pubmed Id: 11263776, UMLKSK CUI: C0024143
HumanFCGR2A2212Fc fragment of IgG, low affinity IIa, receptor (CD32)
img GENERIF, Score=1000, Pubmed Id: 12115187, UMLKSK CUI: C0024143
img GAD, Score=1000, Pubmed Id: 11263776, UMLKSK CUI: C0024143
HumanDUSP11843dual specificity phosphatase 1
img GENERIF, Score=1000, Pubmed Id: 12765304, UMLKSK CUI: C0024143
HumanACE1636angiotensin I converting enzyme
img GENERIF, Score=1000, Pubmed Id: 12043886, UMLKSK CUI: C0024143
img GENERIF, Score=1000, Pubmed Id: 15338496, UMLKSK CUI: C0024143
HumanCCR51234chemokine (C-C motif) receptor 5 (gene/pseudogene)
img GENERIF, Score=1000, Pubmed Id: 12913933, UMLKSK CUI: C0024143
img GENERIF, Score=734, Pubmed Id: 17585540, UMLKSK CUI: C0024143
HumanCD40LG959CD40 ligand
img GENERIF, Score=651, Pubmed Id: 14617752, UMLKSK CUI: C0024143
HumanCASP3836caspase 3, apoptosis-related cysteine peptidase
img GENERIF, Score=734, Pubmed Id: 16931214, UMLKSK CUI: C0024143
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0024143Lupus Nephritis0self