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Details
Link-It Detail - Disease - Pulmonary Disease, Chronic Obstructive
Debug Stats
  • ### Total Build Time: 395 ms 50.322 KB
  • CONCEPT_NAME gt=12 ms Completed: 12 ms rowSize= 438 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 685 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=9 ms Completed: 9 ms rowSize= 562 bytes
  • CONCEPT_CHILDREN gt=7 ms Completed: 7 ms rowSize= 557 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=4 ms Completed: 4 ms rowSize= 1.513 KB
  • CONCEPT_RELATIONSHIPS gt=275 ms Completed: 275 ms rowSize= 15.417 KB
  • CONCEPT_GENES gt=79 ms Completed: 79 ms rowSize= 29.820 KB
  • CONCEPT_XREFS gt=7 ms Completed: 7 ms rowSize= 1.172 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
Pulmonary Disease, Chronic Obstructive C0024117
Chronic Obstructive Airway Disease
Definition (1)
A chronic and progressive lung disorder characterized by the loss of elasticity of the bronchial tree and the air sacs, destruction of the air sacs wall, thickening of the bronchial wall, and mucous accumulation in the bronchial tree. The pathologic changes result in the disruption of the air flow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough, and chest tightness. The two main types of chronic obstructive pulmonary disease are chronic obstructive bronchitis and emphysema.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (1)
img Lung Diseases, Obstructive C0600260
Children (1)
img Bronchitis, Chronic C0008677
Ancestral Roots
RootRoot Plus OneDepthParent
img Respiratory Tract Diseases C0035242img Lung Diseases C00241154img Lung Diseases, Obstructive C0600260
Relationships (230)

Relation Types:
diso_​to_​anat : 27
diso_​to_​chem : 69
diso_​to_​diso : 96
diso_​to_​gene : 3
diso_​to_​phen : 7
diso_​to_​phys : 28


Relationships:
none : 202
associated_​with : 2
classified_​as : 1
entry_​version_​of : 1
gene_​associated_​with_​disease : 2
gene_​product_​malfunction_​associated_​with_​disease : 1
is_​associated_​anatomic_​site_​of : 2
isa : 10
location_​of : 1
parent_​is_​cdrh : 1
related_​to : 6
use : 1
Page Size
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  Page 1 of 10
Prior Page
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Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO1609img Complication Aspects C1171258
DISO_to_DISO889img Complication Aspects C1171258
DISO_to_CHEM681img Agents, Bronchial-Dilating C0006280
DISO_to_DISO674img Asthma C0004096
DISO_to_DISO544img Asthma C0004096
DISO_to_PHEN504img genetic aspects C0017399
DISO_to_ANAT477img In Blood C0005768
DISO_to_ANAT444img Lung C0024109
DISO_to_CHEM435img Agents, Bronchial-Dilating C0006280
DISO_to_DISO261img Dyspnea C0013404
DISO_to_CHEM249img Derivatives, Scopolamine C0036443
DISO_to_ANAT227img In Blood C0005768
DISO_to_PHYS224img Exercise Tolerance C0162521
DISO_to_PHEN213img genetic aspects C0017399
DISO_to_DISO211img Lung Neoplasms C0024121
DISO_to_CHEM181img Adrenal Cortex Hormones C0001617
DISO_to_CHEM167img 1,3-Benzenedimethanol, alpha1-(((1,1-dimethylethyl)amino)methyl)-4-hydroxy- C0001927
DISO_to_DISO155img Dyspnea C0013404
DISO_to_DISO153img Inflammation C0021368
DISO_to_CHEM151img Adrenal Cortex Hormones C0001617
DISO_to_ANAT140img Lung C0024109
DISO_to_CHEM140img 1,3-Benzenedimethanol, alpha1-(((1,1-dimethylethyl)amino)methyl)-4-hydroxy- C0001927
DISO_to_CHEM140img Albuterol C0001927
DISO_to_CHEM139img Adrenergic beta-Agonists C0001644
DISO_to_DISO133img Pulmonary Emphysema C0034067
Genes (149)

Species:
human : 149
Page Size
Current 25
  Page 1 of 6
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanMUC5B727897mucin 5B, oligomeric mucus/gel-forming
img GENERIF, Score=1000, Pubmed Id: 18776153, UMLKSK CUI: C0024117
HumanSFTPA1653509surfactant protein A1
img GENERIF, Score=861, Pubmed Id: 18595202, UMLKSK CUI: C0024117
HumanCOPD260431Pulmonary disease, chronic obstructive, severe early-onset
img GENERIF, Score=1000, Pubmed Id: 12838617, UMLKSK CUI: C0024117
HumanIL27246778interleukin 27
img GENERIF, Score=1000, Pubmed Id: 18554158, UMLKSK CUI: C0024117
HumanFLCN201163folliculin
img GENERIF, Score=861, Pubmed Id: 19116017, UMLKSK CUI: C0024117
HumanFBXO32114907F-box protein 32
img GENERIF, Score=1000, Pubmed Id: 17478621, UMLKSK CUI: C0024117
HumanTSLP85480thymic stromal lymphopoietin
img GENERIF, Score=734, Pubmed Id: 17513456, UMLKSK CUI: C0024117
img GENERIF, Score=1000, Pubmed Id: 18684970, UMLKSK CUI: C0024117
img GENERIF, Score=861, Pubmed Id: 18941246, UMLKSK CUI: C0024117
HumanTRIM6384676tripartite motif containing 63, E3 ubiquitin protein ligase
img GENERIF, Score=1000, Pubmed Id: 17478621, UMLKSK CUI: C0024117
HumanDUOX153905dual oxidase 1
img GENERIF, Score=1000, Pubmed Id: 18177232, UMLKSK CUI: C0024117
HumanDUOX250506dual oxidase 2
img GENERIF, Score=1000, Pubmed Id: 18177232, UMLKSK CUI: C0024117
HumanEFEMP230008EGF containing fibulin-like extracellular matrix protein 2
INFERRED, Score=800, UMLKSK CUI: C0024117
HumanPLA2G2D26279phospholipase A2, group IID
img GENERIF, Score=1000, Pubmed Id: 16002569, UMLKSK CUI: C0024117
HumanSIRT123411sirtuin 1
img GENERIF, Score=1000, Pubmed Id: 18174544, UMLKSK CUI: C0024117
HumanATF622926activating transcription factor 6
img GENERIF, Score=1000, Pubmed Id: 18635891, UMLKSK CUI: C0024117
HumanGPR18211318G protein-coupled receptor 182
img GENERIF, Score=1000, Pubmed Id: 14720432, UMLKSK CUI: C0024117
HumanPARK711315parkinson protein 7
img GENERIF, Score=660, Pubmed Id: 18556627, UMLKSK CUI: C0024117
HumanCXCR610663chemokine (C-X-C motif) receptor 6
img GENERIF, Score=771, Pubmed Id: 17640964, UMLKSK CUI: C0024117
HumanFBLN510516fibulin 5
INFERRED, Score=800, UMLKSK CUI: C0024117
HumanSPAR9981
img GAD, Score=1000, Pubmed Id: 15696492, UMLKSK CUI: C0024117
HumanGSTO19446glutathione S-transferase omega 1
img GENERIF, Score=1000, Pubmed Id: 17617905, UMLKSK CUI: C0024117
HumanADIPOQ9370adiponectin, C1Q and collagen domain containing
img GENERIF, Score=1000, Pubmed Id: 17625082, UMLKSK CUI: C0024117
img GENERIF, Score=1000, Pubmed Id: 19109202, UMLKSK CUI: C0024117
HumanC5orf139315
INFERRED, Score=800, UMLKSK CUI: C0024117
HumanSLC16A49122solute carrier family 16, member 4
img GENERIF, Score=1000, Pubmed Id: 18635880, UMLKSK CUI: C0024117
HumanTNFRSF10A8797tumor necrosis factor receptor superfamily, member 10a
INFERRED, Score=800, UMLKSK CUI: C0024117
HumanTNFRSF10B8795tumor necrosis factor receptor superfamily, member 10b
INFERRED, Score=800, UMLKSK CUI: C0024117
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0024117Pulmonary Disease, Chronic Obstructive0self