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Details
Link-It Detail - Disease - Liver Diseases
Debug Stats
  • ### Total Build Time: 218 ms 54.630 KB
  • CONCEPT_NAME gt=17 ms Completed: 17 ms rowSize= 326 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 1.346 KB
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 561 bytes
  • CONCEPT_CHILDREN gt=10 ms Completed: 10 ms rowSize= 9.975 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.119 KB
  • CONCEPT_RELATIONSHIPS gt=116 ms Completed: 116 ms rowSize= 15.147 KB
  • CONCEPT_GENES gt=73 ms Completed: 73 ms rowSize= 24.817 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.148 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Liver Diseases C0023895
Definition (1)

Your liver is the largest organ inside your body. It is also one of the most important. The liver has many jobs, including changing food into energy and cleaning alcohol and poisons from the blood. Your liver also makes bile, a yellowish-green liquid that helps with digestion.

There are many kinds of liver diseases. Viruses cause some of them, like hepatitis A, hepatitis B and hepatitis C. Others can be the result of drugs, poisons or drinking too much alcohol. If the liver forms scar tissue because of an illness, it's called cirrhosis. Jaundice, or yellowing of the skin, can be one sign of liver disease.

Like other parts of your body, cancer can affect the liver. You could also inherit a liver disease such as hemochromatosis.

Semantic Types (1)
Disease or Syndrome (T047)
Parents (1)
img Digestive System Diseases C0012242
Children (23)
img Hepatitis C0019158
img alpha 1-Antitrypsin Deficiency C0221757
img Tuberculosis, Hepatic C0041313
img Budd-Chiari Syndrome C0856761
img Hepatopulmonary Syndrome C0600452
img Hepatic Insufficiency C1306571
img Liver Neoplasms C0023903
img Focal Nodular Hyperplasia C0333980
img Hepatolenticular Degeneration C0019202
img Liver Diseases, Parasitic C0023897
img Hepatomegaly C0019209
img Peliosis Hepatis C0030781
img Hepatic Veno-Occlusive Disease C0019156
img Liver Diseases, Alcoholic C0023896
img Cholestasis, Intrahepatic C0008372
img Liver Abscess C0023885
img Porphyrias, Hepatic C0162533
img Hepatorenal Syndrome C0019212
img Hypertension, Portal C0020541
img Liver Cirrhosis C0023890
img Fatty Liver C0015695
img Zellweger Syndrome C0043459
img Drug-Induced Liver Injury C0860207
Ancestral Roots
RootRoot Plus OneDepthParent
img Digestive System Diseases C00122422img Digestive System Diseases C0012242
Relationships (384)

Relation Types:
diso_​to_​anat : 27
diso_​to_​chem : 101
diso_​to_​diso : 239
diso_​to_​phen : 2
diso_​to_​phys : 15


Relationships:
none : 247
associated_​with : 3
classifies : 2
entry_​version_​of : 1
induces : 2
is_​associated_​anatomic_​site_​of : 2
isa : 64
location_​of : 1
mapped_​to : 15
may_​diagnose : 30
may_​treat : 6
related_​to : 11
Page Size
Current 25
  Page 1 of 16
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANAT816img Liver C0023884
DISO_to_DISO693img Complication Aspects C1171258
DISO_to_ANAT550img Liver C0023884
DISO_to_DISO487img Complication Aspects C1171258
DISO_to_ANAT350img In Blood C0005768
DISO_to_PHEN270img genetic aspects C0017399
DISO_to_DISO250img Cyst C0010709
DISO_to_ANAT212img In Blood C0005768
DISO_to_DISO193img Cyst C0010709
DISO_to_DISO187img Liver Neoplasms C0023903
DISO_to_PHEN172img genetic aspects C0017399
DISO_to_DISO156img Damage, Reperfusion C0035126
DISO_to_DISO153img Liver Neoplasms C0023903
DISO_to_ANAT120img Hepatocyte C0227525
DISO_to_CHEM101img Antioxidants C0003402
DISO_to_DISO101img Kidney Diseases C0022658
DISO_to_DISO100img Disease, Drug-Induced Liver C0860207
DISO_to_DISO97img Biliary Tract Diseases C0005424
DISO_to_ANAT87img Hepatocyte C0227525
DISO_to_DISO86img Damage, Reperfusion C0035126
DISO_to_DISO86img Disease, Drug-Induced Liver C0860207
DISO_to_DISO80img Biliary Tract Diseases C0005424
DISO_to_CHEM78img Contrast Media C0009924
DISO_to_DISO74img COMPL POSTOP C0032787
DISO_to_DISO74img Carcinoma, Hepatocellular C2239176
Genes (1426)

Species:
human : 1421
mouse : 5
Page Size
Current 25
  Page 1 of 58
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
MouseTXNIP10628thioredoxin interacting protein
img NCI, Score=801, Pubmed Id: 16607285, UMLKSK CUI: C0023895
MouseTIMP17076TIMP metallopeptidase inhibitor 1
img NCI, Score=801, Pubmed Id: 10459021, UMLKSK CUI: C0023895
MouseTNFRSF93604tumor necrosis factor receptor superfamily, member 9
img NCI, Score=801, Pubmed Id: 14871848, UMLKSK CUI: C0023895
MouseIL1RN3557interleukin 1 receptor antagonist
img NCI, Score=801, Pubmed Id: 10496524, UMLKSK CUI: C0023895
img NCI, Score=801, Pubmed Id: 10496524, UMLKSK CUI: C0023895
MouseHDGF3068hepatoma-derived growth factor
img NCI, Score=801, Pubmed Id: 14535987, UMLKSK CUI: C0023895
HumanLOC100507436100507436
INFERRED, Score=800, UMLKSK CUI: C0023895
HumanZGLP1100125288zinc finger, GATA-like protein 1
INFERRED, Score=800, UMLKSK CUI: C0023895
HumanOCTN3100049579organic cation transporter 3
INFERRED, Score=800, UMLKSK CUI: C0023895
HumanCCR2729230chemokine (C-C motif) receptor 2
INFERRED, Score=800, UMLKSK CUI: C0023895
HumanHULC728655hepatocellular carcinoma up-regulated long non-coding RNA
INFERRED, Score=800, UMLKSK CUI: C0023895
HumanGGT2728441gamma-glutamyltransferase 2
img NCI, Score=801, Pubmed Id: 2893671, UMLKSK CUI: C0023895
img NCI, Score=801, Pubmed Id: 6148050, UMLKSK CUI: C0023895
HumanZG16653808zymogen granule protein 16
INFERRED, Score=800, UMLKSK CUI: C0023895
HumanNCF1653361neutrophil cytosolic factor 1
INFERRED, Score=800, UMLKSK CUI: C0023895
HumanLOC652799652799
INFERRED, Score=800, UMLKSK CUI: C0023895
HumanHEPN1641654hepatocellular carcinoma, down-regulated 1
INFERRED, Score=800, UMLKSK CUI: C0023895
HumanPIM3415116pim-3 oncogene
INFERRED, Score=800, UMLKSK CUI: C0023895
HumanMIR223407008microRNA 223
INFERRED, Score=800, UMLKSK CUI: C0023895
HumanMIR21406991microRNA 21
INFERRED, Score=800, UMLKSK CUI: C0023895
HumanMIR146A406938microRNA 146a
INFERRED, Score=800, UMLKSK CUI: C0023895
HumanMIR122406906microRNA 122
INFERRED, Score=800, UMLKSK CUI: C0023895
HumanNHLRC1378884NHL repeat containing 1
INFERRED, Score=800, UMLKSK CUI: C0023895
HumanMIA3375056melanoma inhibitory activity family, member 3
INFERRED, Score=800, UMLKSK CUI: C0023895
HumanGLDN342035gliomedin
INFERRED, Score=800, UMLKSK CUI: C0023895
HumanHIST2H3A333932histone cluster 2, H3a
INFERRED, Score=800, UMLKSK CUI: C0023895
HumanSNAI3333929snail family zinc finger 3
INFERRED, Score=800, UMLKSK CUI: C0023895
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0023895Liver Diseases0self