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Details
Link-It Detail - Disease - Leukemia-Lymphoma, Adult T-Cell
Debug Stats
  • ### Total Build Time: 262 ms 64.231 KB
  • CONCEPT_NAME gt=6 ms Completed: 6 ms rowSize= 420 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 384 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=6 ms Completed: 6 ms rowSize= 552 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 4.058 KB
  • CONCEPT_RELATIONSHIPS gt=204 ms Completed: 204 ms rowSize= 16.607 KB
  • CONCEPT_GENES gt=41 ms Completed: 41 ms rowSize= 40.859 KB
  • CONCEPT_XREFS gt=4 ms Completed: 4 ms rowSize= 1.165 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
Leukemia-Lymphoma, Adult T-Cell C0023493
Adult T-Cell Lymphoma/Leukemia
Definition (1)
Aggressive T-Cell malignancy with adult onset, caused by HUMAN T-LYMPHOTROPIC VIRUS 1. It is endemic in Japan, the Caribbean basin, Southeastern United States, Hawaii, and parts of Central and South America and sub-Saharan Africa.
Semantic Types (1)
Neoplastic Process (T191)
Parents (1)
img Leukemia, T-Cell C0023492
Ancestral Roots
RootRoot Plus OneDepthParent
img Neoplasms C0027651img Neoplasms by Histologic Type C00276526img Leukemia, T-Cell C0023492
img Immune System Diseases C0021053img Immunoproliferative Disorders C00210706img Leukemia, T-Cell C0023492
img Hemic and Lymphatic Diseases C0018981img Lymphatic Diseases C00242286img Leukemia, T-Cell C0023492
Relationships (124)

Relation Types:
diso_​to_​anat : 29
diso_​to_​chem : 37
diso_​to_​diso : 40
diso_​to_​gene : 4
diso_​to_​phen : 2
diso_​to_​phys : 12


Relationships:
none : 74
clinically_​similar : 1
eo_​disease_​maps_​to_​human_​disease : 3
gene_​associated_​with_​disease : 4
gene_​product_​malfunction_​associated_​with_​disease : 1
is_​abnormal_​cell_​of_​disease : 7
is_​associated_​disease_​of : 3
is_​finding_​of_​disease : 1
is_​normal_​cell_​origin_​of_​disease : 5
is_​normal_​tissue_​origin_​of_​disease : 2
is_​not_​abnormal_​cell_​of_​disease : 2
is_​not_​normal_​cell_​origin_​of_​disease : 4
is_​primary_​anatomic_​site_​of_​disease : 2
isa : 12
may_​be_​finding_​of_​disease : 1
permuted_​term_​of : 1
use : 1
Page Size
Current 25
  Page 1 of 5
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_PHEN197img genetic aspects C0017399
DISO_to_PHEN149img genetic aspects C0017399
DISO_to_DISO61img Complication Aspects C1171258
DISO_to_DISO60img Complication Aspects C1171258
DISO_to_DISO42img HTLV-I Infections C0020097
DISO_to_CHEM34img Antineoplastic Agents C0003392
DISO_to_CHEM33img Antineoplastic Agents C0003392
DISO_to_PHYS33img Apoptosis C0162638
DISO_to_CHEM32img Binding Protein, DNA C0012940
DISO_to_CHEM28img TRANSCRIPTION FACTOR C0040648
DISO_to_CHEM28img Transcription Factors C0040648
DISO_to_DISO28img Precursor Cell Lymphoblastic Leukemia Lymphoma C1961102
DISO_to_ANAT25img T-Lymphocytes C0039194
DISO_to_ANAT23img T-Lymphocyte C0039194
DISO_to_ANAT22img In Blood C0005768
DISO_to_CHEM22img Antigen p40x, Transforming C0079407
DISO_to_DISO22img Chromosomal translocation C0040715
DISO_to_PHYS22img Apoptosis C0162638
DISO_to_ANAT21img In Blood C0005768
DISO_to_CHEM21img Cellular Proto Oncogene Proteins C0033712
DISO_to_DISO20img Cutaneous tumor C0037286
DISO_to_CHEM17img Homeo Domain Proteins C0242617
DISO_to_CHEM17img Homeodomain Proteins C0242617
DISO_to_CHEM17img NOTCH 001 RECEPTOR C0144507
DISO_to_CHEM16img Antigen p40x, Transforming C0079407
Genes (79)

Species:
human : 78
mouse : 1
Page Size
Current 25
  Page 1 of 4
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
MouseNOTCH14851notch 1
img NCI, Score=801, Pubmed Id: 9111040, UMLKSK CUI: C0023493
HumanPRDM1663976PR domain containing 16
img GENERIF, Score=1000, Pubmed Id: 14656887, UMLKSK CUI: C0023493
HumanRTN457142reticulon 4
img GENERIF, Score=1000, Pubmed Id: 16646068, UMLKSK CUI: C0023493
HumanFOXP350943forkhead box P3
img NCI, Score=801, Pubmed Id: 15198736, UMLKSK CUI: C0023493
img NCI, Score=801, Pubmed Id: 16108835, UMLKSK CUI: C0023493
img NCI, Score=801, Pubmed Id: 15198736, UMLKSK CUI: C0023493
img NCI, Score=801, Pubmed Id: 15569983, UMLKSK CUI: C0023493
img GENERIF, Score=1000, Pubmed Id: 18246047, UMLKSK CUI: C0023493
img NCI, Score=801, Pubmed Id: 15198736, UMLKSK CUI: C0023493
HumanTLX330012T-cell leukemia homeobox 3
img GENERIF, Score=1000, Pubmed Id: 17308084, UMLKSK CUI: C0023493
img GENERIF, Score=1000, Pubmed Id: 15990867, UMLKSK CUI: C0023493
img GENERIF, Score=1000, Pubmed Id: 12970786, UMLKSK CUI: C0023493
HumanIKZF222807IKAROS family zinc finger 2 (Helios)
img NCI, Score=801, Pubmed Id: 12648068, UMLKSK CUI: C0023493
img NCI, Score=801, Pubmed Id: 12648068, UMLKSK CUI: C0023493
img NCI, Score=801, Pubmed Id: 12648068, UMLKSK CUI: C0023493
HumanMALT110892mucosa associated lymphoid tissue lymphoma translocation gene 1
img NCI, Score=801, Pubmed Id: 14997743, UMLKSK CUI: C0023493
HumanPIAS310401protein inhibitor of activated STAT, 3
img GENERIF, Score=1000, Pubmed Id: 14630083, UMLKSK CUI: C0023493
HumanGPHN10243gephyrin
img NCI, Score=801, Pubmed Id: 14991527, UMLKSK CUI: C0023493
HumanEBI310148Epstein-Barr virus induced 3
img NCI, Score=801, Pubmed Id: 15793300, UMLKSK CUI: C0023493
HumanMVP9961major vault protein
img GENERIF, Score=1000, Pubmed Id: 17134750, UMLKSK CUI: C0023493
HumanIL329235interleukin 32
img GENERIF, Score=1000, Pubmed Id: 18289868, UMLKSK CUI: C0023493
HumanIL1RL19173interleukin 1 receptor-like 1
img NCI, Score=801, Pubmed Id: 14721775, UMLKSK CUI: C0023493
img NCI, Score=801, Pubmed Id: 14721775, UMLKSK CUI: C0023493
HumanEBAG99166estrogen receptor binding site associated, antigen, 9
img NCI, Score=801, Pubmed Id: 15218962, UMLKSK CUI: C0023493
img NCI, Score=801, Pubmed Id: 15218962, UMLKSK CUI: C0023493
img NCI, Score=801, Pubmed Id: 15218962, UMLKSK CUI: C0023493
HumanTNFRSF6B8771tumor necrosis factor receptor superfamily, member 6b, decoy
img NCI, Score=801, Pubmed Id: 11098089, UMLKSK CUI: C0023493
img NCI, Score=801, Pubmed Id: 11098089, UMLKSK CUI: C0023493
HumanTNFSF108743tumor necrosis factor (ligand) superfamily, member 10
img GENERIF, Score=1000, Pubmed Id: 17495957, UMLKSK CUI: C0023493
HumanSOCS18651suppressor of cytokine signaling 1
img GENERIF, Score=1000, Pubmed Id: 14630083, UMLKSK CUI: C0023493
HumanKDM5D8284lysine (K)-specific demethylase 5D
img GAD, Score=1000, Pubmed Id: 11325850, UMLKSK CUI: C0023493
HumanTP537157tumor protein p53
img GAD, Score=1000, Pubmed Id: 8180387, UMLKSK CUI: C0023493
HumanTNFRSF1B7133tumor necrosis factor receptor superfamily, member 1B
img NCI, Score=801, Pubmed Id: 11163081, UMLKSK CUI: C0023493
HumanTNF7124tumor necrosis factor
img GAD, Score=1000, Pubmed Id: 11325850, UMLKSK CUI: C0023493
HumanTGFB17040transforming growth factor, beta 1
img GENERIF, Score=1000, Pubmed Id: 18467597, UMLKSK CUI: C0023493
HumanTFRC7037transferrin receptor (p90, CD71)
img NCI, Score=801, Pubmed Id: 1585922, UMLKSK CUI: C0023493
HumanTERF27014telomeric repeat binding factor 2
img GENERIF, Score=1000, Pubmed Id: 16786598, UMLKSK CUI: C0023493
HumanTERF17013telomeric repeat binding factor (NIMA-interacting) 1
img GENERIF, Score=1000, Pubmed Id: 16786598, UMLKSK CUI: C0023493
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0023493Leukemia-Lymphoma, Adult T-Cell0self