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Details
Link-It Detail - Disease - Leukemia, Promyelocytic, Acute
Debug Stats
  • ### Total Build Time: 211 ms 63.544 KB
  • CONCEPT_NAME gt=4 ms Completed: 4 ms rowSize= 358 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 297 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 560 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=5 ms Completed: 5 ms rowSize= 1.509 KB
  • CONCEPT_RELATIONSHIPS gt=148 ms Completed: 148 ms rowSize= 17.012 KB
  • CONCEPT_GENES gt=44 ms Completed: 44 ms rowSize= 42.455 KB
  • CONCEPT_XREFS gt=6 ms Completed: 6 ms rowSize= 1.164 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Leukemia, Promyelocytic, Acute C0023487
Definition (1)
An acute myeloid leukemia in which abnormal PROMYELOCYTES predominate. It is frequently associated with DISSEMINATED INTRAVASCULAR COAGULATION.
Semantic Types (1)
Neoplastic Process (T191)
Parents (1)
img Leukemia, Myeloid, Acute C0023467
Ancestral Roots
RootRoot Plus OneDepthParent
img Neoplasms C0027651img Neoplasms by Histologic Type C00276526img Leukemia, Myeloid, Acute C0023467
Relationships (149)

Relation Types:
diso_​to_​anat : 23
diso_​to_​chem : 61
diso_​to_​diso : 35
diso_​to_​gene : 14
diso_​to_​phen : 2
diso_​to_​phys : 14


Relationships:
none : 85
expanded_​form_​of : 1
gene_​associated_​with_​disease : 14
gene_​product_​malfunction_​associated_​with_​disease : 1
is_​abnormal_​cell_​of_​disease : 6
is_​associated_​anatomic_​site_​of : 2
is_​cytogenetic_​abnormality_​of_​disease : 2
is_​finding_​of_​disease : 2
is_​normal_​cell_​origin_​of_​disease : 3
is_​normal_​tissue_​origin_​of_​disease : 2
is_​not_​abnormal_​cell_​of_​disease : 1
is_​not_​finding_​of_​disease : 2
is_​not_​normal_​cell_​origin_​of_​disease : 1
isa : 6
may_​be_​abnormal_​cell_​of_​disease : 1
may_​be_​finding_​of_​disease : 2
may_​treat : 16
used_​for : 2
Page Size
Current 25
  Page 1 of 6
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_PHEN327img genetic aspects C0017399
DISO_to_PHEN250img genetic aspects C0017399
DISO_to_CHEM206img Antineoplastic Agents C0003392
DISO_to_CHEM204img Antineoplastic Agents C0003392
DISO_to_CHEM193img Tretinoin C0040845
DISO_to_CHEM178img Tretinoin C0040845
DISO_to_CHEM137img Arsenicals C0003819
DISO_to_CHEM134img Oxides C0030015
DISO_to_CHEM133img ARSENIC CPDS C0003819
DISO_to_CHEM118img Oxides C0030015
DISO_to_CHEM107img NEOPL PROTEINS C0027642
DISO_to_CHEM105img Oncogene Proteins, Fusion C0029014
DISO_to_DISO102img Complication Aspects C1171258
DISO_to_CHEM87img Chimeric Oncogene Proteins C0029014
DISO_to_PHYS83img Apoptosis C0162638
DISO_to_PHYS81img Apoptosis C0162638
DISO_to_DISO77img Complication Aspects C1171258
DISO_to_PHYS50img Cell Differentiation C0007589
DISO_to_DISO45img Chromosomal translocation C0040715
DISO_to_DISO40img Chromosomal translocation C0040715
DISO_to_ANAT38img In Blood C0005768
DISO_to_ANAT37img Chromosomes, Human, Pair 17 C0008659
DISO_to_CHEM37img TRANSCRIPTION FACTOR C0040648
DISO_to_CHEM37img Transcription Factors C0040648
DISO_to_CHEM36img Nuclear Proteins C0028589
Genes (169)

Species:
human : 167
mouse : 2
Page Size
Current 25
  Page 1 of 7
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
MouseVCAM17412vascular cell adhesion molecule 1
img NCI, Score=801, Pubmed Id: 11157679, UMLKSK CUI: C0023487
img NCI, Score=801, Pubmed Id: 10453040, UMLKSK CUI: C0023487
MouseSPI16688spleen focus forming virus (SFFV) proviral integration oncogene
img NCI, Score=801, Pubmed Id: 16113082, UMLKSK CUI: C0023487
img NCI, Score=801, Pubmed Id: 16113082, UMLKSK CUI: C0023487
img NCI, Score=801, Pubmed Id: 16113082, UMLKSK CUI: C0023487
HumanRAB7B338382RAB7B, member RAS oncogene family
img NCI, Score=801, Pubmed Id: 15144907, UMLKSK CUI: C0023487
img NCI, Score=801, Pubmed Id: 15144907, UMLKSK CUI: C0023487
img NCI, Score=801, Pubmed Id: 15144907, UMLKSK CUI: C0023487
HumanMYADM91663myeloid-associated differentiation marker
img NCI, Score=801, Pubmed Id: 12075932, UMLKSK CUI: C0023487
HumanPRAM184106PML-RARA regulated adaptor molecule 1
Click here to display 6 evidence detail records.
HumanSH3BGRL383442SH3 domain binding glutamic acid-rich protein like 3
img NCI, Score=801, Pubmed Id: 15907482, UMLKSK CUI: C0023487
HumanTNKS280351tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
img NCI, Score=801, Pubmed Id: 16207594, UMLKSK CUI: C0023487
img NCI, Score=801, Pubmed Id: 16207594, UMLKSK CUI: C0023487
HumanRNF2679102ring finger protein 26
img NCI, Score=801, Pubmed Id: 11352657, UMLKSK CUI: C0023487
HumanMBD353615methyl-CpG binding domain protein 3
img GENERIF, Score=1000, Pubmed Id: 18644863, UMLKSK CUI: C0023487
HumanASB251676ankyrin repeat and SOCS box containing 2
img NCI, Score=801, Pubmed Id: 11682484, UMLKSK CUI: C0023487
img NCI, Score=801, Pubmed Id: 11682484, UMLKSK CUI: C0023487
HumanPIAS451588protein inhibitor of activated STAT, 4
img GENERIF, Score=734, Pubmed Id: 16219678, UMLKSK CUI: C0023487
HumanDBNL28988drebrin-like
img NCI, Score=801, Pubmed Id: 15637062, UMLKSK CUI: C0023487
HumanPPP2R3B28227protein phosphatase 2, regulatory subunit B'', beta
img NCI, Score=801, Pubmed Id: 10924227, UMLKSK CUI: C0023487
HumanZBTB3227033zinc finger and BTB domain containing 32
img NCI, Score=801, Pubmed Id: 15542853, UMLKSK CUI: C0023487
HumanZNF45126036zinc finger protein 451
img GENERIF, Score=734, Pubmed Id: 18656483, UMLKSK CUI: C0023487
HumanSP14011262SP140 nuclear body protein
img NCI, Score=801, Pubmed Id: 8910577, UMLKSK CUI: C0023487
HumanCHEK211200checkpoint kinase 2
Click here to display 7 evidence detail records.
HumanPRDX410549peroxiredoxin 4
img NCI, Score=801, Pubmed Id: 15188461, UMLKSK CUI: C0023487
HumanYAP110413Yes-associated protein 1
img GENERIF, Score=673, Pubmed Id: 19111660, UMLKSK CUI: C0023487
HumanTOPORS10210topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
img NCI, Score=801, Pubmed Id: 12083797, UMLKSK CUI: C0023487
HumanTOB110140transducer of ERBB2, 1
img NCI, Score=801, Pubmed Id: 12435401, UMLKSK CUI: C0023487
HumanZBTB3310009zinc finger and BTB domain containing 33
img NCI, Score=801, Pubmed Id: 10207085, UMLKSK CUI: C0023487
img NCI, Score=801, Pubmed Id: 10207085, UMLKSK CUI: C0023487
HumanMVP9961major vault protein
img NCI, Score=801, Pubmed Id: 10792272, UMLKSK CUI: C0023487
img NCI, Score=801, Pubmed Id: 10792272, UMLKSK CUI: C0023487
img NCI, Score=801, Pubmed Id: 15108169, UMLKSK CUI: C0023487
HumanISG159636ISG15 ubiquitin-like modifier
img NCI, Score=801, Pubmed Id: 14976209, UMLKSK CUI: C0023487
img NCI, Score=801, Pubmed Id: 14976209, UMLKSK CUI: C0023487
img NCI, Score=801, Pubmed Id: 14976209, UMLKSK CUI: C0023487
img NCI, Score=801, Pubmed Id: 14976209, UMLKSK CUI: C0023487
HumanNCOR29612nuclear receptor corepressor 2
img NCI, Score=801, Pubmed Id: 11585900, UMLKSK CUI: C0023487
img NCI, Score=801, Pubmed Id: 11585900, UMLKSK CUI: C0023487
img NCI, Score=801, Pubmed Id: 9256429, UMLKSK CUI: C0023487
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0023487Leukemia, Promyelocytic, Acute0self