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Details
Link-It Detail - Disease - Leukemia, Myeloid
Debug Stats
  • ### Total Build Time: 427 ms 61.729 KB
  • CONCEPT_NAME gt=9 ms Completed: 9 ms rowSize= 332 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 324 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=6 ms Completed: 6 ms rowSize= 544 bytes
  • CONCEPT_CHILDREN gt=7 ms Completed: 7 ms rowSize= 3.212 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.493 KB
  • CONCEPT_RELATIONSHIPS gt=211 ms Completed: 211 ms rowSize= 16.580 KB
  • CONCEPT_GENES gt=190 ms Completed: 190 ms rowSize= 37.911 KB
  • CONCEPT_XREFS gt=3 ms Completed: 3 ms rowSize= 1.151 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Leukemia, Myeloid C0023470
Definition (1)
Form of leukemia characterized by an uncontrolled proliferation of the myeloid lineage and their precursors (MYELOID PROGENITOR CELLS) in the bone marrow and other sites.
Semantic Types (1)
Neoplastic Process (T191)
Parents (1)
img Leukemia C0023418
Children (7)
img Leukemia, Myeloid, Acute C0023467
img Leukemia, Myelomonocytic, Acute C0023479
img Leukemia, Myelomonocytic, Chronic C0023480
img Sarcoma, Myeloid C0152276
img Leukemia, Myelogenous, Chronic, BCR-ABL Positive C0023473
img Leukemia, Myelomonocytic, Juvenile C0349639
img Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative C1292772
Ancestral Roots
RootRoot Plus OneDepthParent
img Neoplasms C0027651img Neoplasms by Histologic Type C00276524img Leukemia C0023418
Relationships (171)

Relation Types:
diso_​to_​anat : 30
diso_​to_​chem : 56
diso_​to_​diso : 52
diso_​to_​gene : 14
diso_​to_​phen : 2
diso_​to_​phys : 17


Relationships:
none : 119
associated_​with : 2
classifies : 1
eo_​disease_​maps_​to_​human_​disease : 6
gene_​associated_​with_​disease : 13
gene_​product_​malfunction_​associated_​with_​disease : 1
is_​abnormal_​cell_​of_​disease : 5
is_​associated_​anatomic_​site_​of : 1
is_​normal_​cell_​origin_​of_​disease : 2
is_​normal_​tissue_​origin_​of_​disease : 2
is_​not_​finding_​of_​disease : 1
is_​not_​normal_​cell_​origin_​of_​disease : 1
is_​primary_​anatomic_​site_​of_​disease : 1
isa : 13
mapped_​to : 1
use : 2
Page Size
Current 25
  Page 1 of 7
Prior Page
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Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_PHEN896img genetic aspects C0017399
DISO_to_PHEN396img genetic aspects C0017399
DISO_to_DISO178img Dysmyelopoietic Syndromes C0026986
DISO_to_DISO169img Complication Aspects C1171258
DISO_to_CHEM152img Antineoplastic Agents C0003392
DISO_to_CHEM132img Cellular Proto Oncogene Proteins C0033712
DISO_to_CHEM124img Binding Protein, DNA C0012940
DISO_to_DISO121img Precursor Cell Lymphoblastic Leukemia Lymphoma C1961102
DISO_to_CHEM120img TRANSCRIPTION FACTOR C0040648
DISO_to_DISO101img Chromosomal translocation C0040715
DISO_to_CHEM97img NEOPL PROTEINS C0027642
DISO_to_CHEM96img Oncogene Proteins, Fusion C0029014
DISO_to_ANAT90img In Blood C0005768
DISO_to_PHYS90img Apoptosis C0162638
DISO_to_DISO84img Chromosome Aberrations C0008625
DISO_to_CHEM77img Receptor Protein-Tyrosine Kinases C0206364
DISO_to_DISO72img Dysmyelopoietic Syndromes C0026986
DISO_to_PHYS70img Mutation C0026882
DISO_to_CHEM67img Antineoplastic Agents C0003392
DISO_to_CHEM66img Antibodies, Monoclonal C0003250
DISO_to_DISO65img Complication Aspects C1171258
DISO_to_DISO61img METACHRONOUS NEOPL C0085183
DISO_to_CHEM56img .beta.-Cytosine arabinoside C0010711
DISO_to_CHEM50img NEOPL PROTEINS C0027642
DISO_to_DISO50img chemically induced C0007994
Genes (960)

Species:
human : 929
mouse : 31
Page Size
Current 25
  Page 1 of 39
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
MouseBCL11A53335B-cell CLL/lymphoma 11A (zinc finger protein)
img NCI, Score=801, Pubmed Id: 10757802, UMLKSK CUI: C0023470
img NCI, Score=801, Pubmed Id: 11161790, UMLKSK CUI: C0023470
MouseBATF10538basic leucine zipper transcription factor, ATF-like
img NCI, Score=801, Pubmed Id: 12444555, UMLKSK CUI: C0023470
MouseMRVI110335murine retrovirus integration site 1 homolog
img NCI, Score=801, Pubmed Id: 10321731, UMLKSK CUI: C0023470
img NCI, Score=801, Pubmed Id: 10321731, UMLKSK CUI: C0023470
MouseSOCS39021suppressor of cytokine signaling 3
img NCI, Score=801, Pubmed Id: 9266833, UMLKSK CUI: C0023470
MouseCCNA18900cyclin A1
img NCI, Score=801, Pubmed Id: 11381140, UMLKSK CUI: C0023470
MouseSOCS28835suppressor of cytokine signaling 2
img NCI, Score=801, Pubmed Id: 9266833, UMLKSK CUI: C0023470
MouseWNT5A7474wingless-type MMTV integration site family, member 5A
img NCI, Score=801, Pubmed Id: 14667502, UMLKSK CUI: C0023470
MouseVIS17435viral integration site 1
Click here to display 3 evidence detail records.
MouseVCAM17412vascular cell adhesion molecule 1
img NCI, Score=801, Pubmed Id: 11746860, UMLKSK CUI: C0023470
MouseTFRC7037transferrin receptor (p90, CD71)
img NCI, Score=801, Pubmed Id: 6291530, UMLKSK CUI: C0023470
MouseTEC7006transient erythroblastopenia of childhood
img NCI, Score=801, Pubmed Id: 7678927, UMLKSK CUI: C0023470
MouseSTAT36774signal transducer and activator of transcription 3 (acute-phase response factor)
img NCI, Score=801, Pubmed Id: 12444555, UMLKSK CUI: C0023470
MouseSPI16688spleen focus forming virus (SFFV) proviral integration oncogene
img NCI, Score=801, Pubmed Id: 15304397, UMLKSK CUI: C0023470
MouseNME14830NME/NM23 nucleoside diphosphate kinase 1
img NCI, Score=801, Pubmed Id: 8896423, UMLKSK CUI: C0023470
img NCI, Score=801, Pubmed Id: 7612661, UMLKSK CUI: C0023470
MouseMPL4352myeloproliferative leukemia virus oncogene
img NCI, Score=801, Pubmed Id: 15234571, UMLKSK CUI: C0023470
img NCI, Score=801, Pubmed Id: 8898102, UMLKSK CUI: C0023470
MouseMLLT34300myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
img NCI, Score=801, Pubmed Id: 9418860, UMLKSK CUI: C0023470
MouseMIF4282macrophage migration inhibitory factor (glycosylation-inhibiting factor)
img NCI, Score=801, Pubmed Id: 6989921, UMLKSK CUI: C0023470
MouseMEIS14211Meis homeobox 1
Click here to display 9 evidence detail records.
MouseJUNB3726jun B proto-oncogene
img NCI, Score=801, Pubmed Id: 8275499, UMLKSK CUI: C0023470
MouseIL33562interleukin 3 (colony-stimulating factor, multiple)
Click here to display 4 evidence detail records.
MouseHSPA83312heat shock 70kDa protein 8
img NCI, Score=801, Pubmed Id: 7796466, UMLKSK CUI: C0023470
MouseHOXB83218homeobox B8
img NCI, Score=801, Pubmed Id: 2564662, UMLKSK CUI: C0023470
MouseHOXA93205homeobox A9
Click here to display 7 evidence detail records.
MouseHOXA73204homeobox A7
Click here to display 3 evidence detail records.
MouseHMGB23148high mobility group box 2
img NCI, Score=801, Pubmed Id: 6219031, UMLKSK CUI: C0023470
img NCI, Score=801, Pubmed Id: 6219031, UMLKSK CUI: C0023470
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0023470Leukemia, Myeloid0self