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Details
Link-It Detail - Disease - Leukemia, Myeloid, Acute
Debug Stats
  • ### Total Build Time: 853 ms 60.302 KB
  • CONCEPT_NAME gt=8 ms Completed: 8 ms rowSize= 403 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 282 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=15 ms Completed: 15 ms rowSize= 553 bytes
  • CONCEPT_CHILDREN gt=36 ms Completed: 36 ms rowSize= 3.168 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=12 ms Completed: 12 ms rowSize= 1.502 KB
  • CONCEPT_RELATIONSHIPS gt=512 ms Completed: 512 ms rowSize= 17.439 KB
  • CONCEPT_GENES gt=265 ms Completed: 265 ms rowSize= 35.615 KB
  • CONCEPT_XREFS gt=4 ms Completed: 4 ms rowSize= 1.158 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
Leukemia, Myeloid, Acute C0023467
Leukemia, Myelocytic, Acute
Definition (1)
acute leukemia arising from myeloid tissue in which the granular, polymorphonuclear leukocytes and their precursors predominate.
Semantic Types (1)
Neoplastic Process (T191)
Parents (1)
img Leukemia, Myeloid C0023470
Children (7)
img Leukemia, Promyelocytic, Acute C0023487
img Leukemia, Erythroblastic, Acute C0023440
img Leukemia, Basophilic, Acute C0023437
img Leukemia, Mast-Cell C0023461
img Leukemia, Megakaryoblastic, Acute C0023462
img Leukemia, Eosinophilic, Acute C0023439
img Leukemia, Monocytic, Acute C0023465
Ancestral Roots
RootRoot Plus OneDepthParent
img Neoplasms C0027651img Neoplasms by Histologic Type C00276525img Leukemia, Myeloid C0023470
Relationships (305)

Relation Types:
diso_​to_​anat : 38
diso_​to_​chem : 130
diso_​to_​diso : 81
diso_​to_​gene : 32
diso_​to_​phen : 3
diso_​to_​phys : 21


Relationships:
none : 191
associated_​with : 2
clinically_​similar : 2
gene_​associated_​with_​disease : 28
gene_​is_​biomarker_​of : 1
gene_​product_​malfunction_​associated_​with_​disease : 8
is_​abnormal_​cell_​of_​disease : 5
is_​associated_​anatomic_​site_​of : 1
is_​normal_​cell_​origin_​of_​disease : 2
is_​normal_​tissue_​origin_​of_​disease : 2
is_​not_​abnormal_​cell_​of_​disease : 1
is_​not_​finding_​of_​disease : 3
is_​not_​normal_​cell_​origin_​of_​disease : 1
is_​primary_​anatomic_​site_​of_​disease : 1
isa : 28
mapped_​to : 1
may_​treat : 20
related_​to : 7
use : 1
Page Size
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Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_PHEN2149img genetic aspects C0017399
DISO_to_PHEN803img genetic aspects C0017399
DISO_to_DISO491img Complication Aspects C1171258
DISO_to_DISO446img Dysmyelopoietic Syndromes C0026986
DISO_to_CHEM393img Antineoplastic Agents C0003392
DISO_to_DISO367img Precursor Cell Lymphoblastic Leukemia Lymphoma C1961102
DISO_to_PHYS360img Mutation C0026882
DISO_to_DISO283img Precursor Cell Lymphoblastic Leukemia Lymphoma C1961102
DISO_to_CHEM254img fms-Like Tyrosine Kinase 3 C0287186
DISO_to_DISO251img Complication Aspects C1171258
DISO_to_DISO212img Chromosomal translocation C0040715
DISO_to_ANAT184img In Blood C0005768
DISO_to_DISO172img Myelodysplastic Syndromes C0026986
DISO_to_CHEM171img Nuclear Proteins C0028589
DISO_to_CHEM148img Chimeric Oncogene Proteins C0029014
DISO_to_PHYS140img GENE EXPRESSION REG LEUKEMIC C0017267
DISO_to_PHYS139img Apoptosis C0162638
DISO_to_DISO128img Neoplasms, Second Primary C0085183
DISO_to_CHEM123img BIOCHEM TUMOR MARKERS C0041366
DISO_to_CHEM122img .beta.-Cytosine arabinoside C0010711
DISO_to_ANAT114img In Blood C0005768
DISO_to_CHEM114img Core Binding Factor Alpha 2 Subunit C0215508
DISO_to_CHEM112img Antineoplastic Agents C0003392
DISO_to_CHEM111img TRANSCRIPTION FACTOR C0040648
DISO_to_CHEM111img Transcription Factors C0040648
Genes (634)

Species:
human : 613
mouse : 21
Page Size
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SpeciesGeneGeneIdGene NameEvidence
MouseTRIB228951tribbles homolog 2 (Drosophila)
img NCI, Score=801, Pubmed Id: 17097562, UMLKSK CUI: C0023467
MouseCCNA18900cyclin A1
Click here to display 3 evidence detail records.
MouseMLLT108028myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
img NCI, Score=801, Pubmed Id: 17329976, UMLKSK CUI: C0023467
img NCI, Score=801, Pubmed Id: 17097559, UMLKSK CUI: C0023467
MouseTCF36929transcription factor 3
img NCI, Score=801, Pubmed Id: 14729970, UMLKSK CUI: C0023467
MouseSSFA26744sperm specific antigen 2
img NCI, Score=801, Pubmed Id: 12673685, UMLKSK CUI: C0023467
MouseSPI16688spleen focus forming virus (SFFV) proviral integration oncogene
Click here to display 7 evidence detail records.
MousePLAGL25326pleiomorphic adenoma gene-like 2
img NCI, Score=801, Pubmed Id: 15585652, UMLKSK CUI: C0023467
MousePBX15087pre-B-cell leukemia homeobox 1
img NCI, Score=801, Pubmed Id: 14729970, UMLKSK CUI: C0023467
img NCI, Score=801, Pubmed Id: 14729970, UMLKSK CUI: C0023467
MouseNUP984928nucleoporin 98kDa
img NCI, Score=801, Pubmed Id: 12032333, UMLKSK CUI: C0023467
MouseMLLT34300myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
img NCI, Score=801, Pubmed Id: 12242306, UMLKSK CUI: C0023467
MouseMLF14291myeloid leukemia factor 1
img NCI, Score=801, Pubmed Id: 10393836, UMLKSK CUI: C0023467
img NCI, Score=801, Pubmed Id: 10393836, UMLKSK CUI: C0023467
MouseMEIS14211Meis homeobox 1
Click here to display 8 evidence detail records.
MouseIL33562interleukin 3 (colony-stimulating factor, multiple)
img NCI, Score=801, Pubmed Id: 11571641, UMLKSK CUI: C0023467
MouseHOXB83218homeobox B8
img NCI, Score=801, Pubmed Id: 11571641, UMLKSK CUI: C0023467
MouseHOXB43214homeobox B4
img NCI, Score=801, Pubmed Id: 8972230, UMLKSK CUI: C0023467
MouseHOXA103206homeobox A10
Click here to display 3 evidence detail records.
MouseHOXA93205homeobox A9
Click here to display 7 evidence detail records.
MouseMECOM2122MDS1 and EVI1 complex locus
img NCI, Score=801, Pubmed Id: 14724585, UMLKSK CUI: C0023467
MouseCSF11435colony stimulating factor 1 (macrophage)
img NCI, Score=801, Pubmed Id: 9116300, UMLKSK CUI: C0023467
MouseCDX41046caudal type homeobox 4
Click here to display 3 evidence detail records.
MouseCD80941CD80 molecule
img NCI, Score=801, Pubmed Id: 15152266, UMLKSK CUI: C0023467
img NCI, Score=801, Pubmed Id: 15152266, UMLKSK CUI: C0023467
HumanPPBPL1728045
INFERRED, Score=800, UMLKSK CUI: C0023467
HumanLOC644165644165
img NCI, Score=801, Pubmed Id: 2678002, UMLKSK CUI: C0023467
HumanCCL3L3414062chemokine (C-C motif) ligand 3-like 3
img NCI, Score=801, Pubmed Id: 2687328, UMLKSK CUI: C0023467
img NCI, Score=801, Pubmed Id: 8843546, UMLKSK CUI: C0023467
HumanFLJ42953400892
img NCI, Score=801, Pubmed Id: 2678002, UMLKSK CUI: C0023467
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0023467Leukemia, Myeloid, Acute0self