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Details
Link-It Detail - Disease - Leukemia
Debug Stats
  • ### Total Build Time: 1,179 ms 67.354 KB
  • CONCEPT_NAME gt=8 ms Completed: 8 ms rowSize= 314 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=1 ms Completed: 1 ms rowSize= 255 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 564 bytes
  • CONCEPT_CHILDREN gt=32 ms Completed: 32 ms rowSize= 3.975 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.513 KB
  • CONCEPT_RELATIONSHIPS gt=724 ms Completed: 724 ms rowSize= 16.790 KB
  • CONCEPT_GENES gt=410 ms Completed: 410 ms rowSize= 42.618 KB
  • CONCEPT_XREFS gt=3 ms Completed: 3 ms rowSize= 1.143 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Leukemia C0023418
Definition (1)
A progressive, proliferative disease of blood cells, originating from myeloid or lymphoid stem cells.
Semantic Types (1)
Neoplastic Process (T191)
Parents (1)
img Neoplasms by Histologic Type C0027652
Children (9)
img Leukemia, Mast-Cell C0023461
img Leukemia, Experimental C0023441
img Leukemia, Radiation-Induced C0023488
img Leukemia, Hairy Cell C0023443
img Leukemia, Myeloid C0023470
img Leukemia, Lymphoid C0023448
img Enzootic Bovine Leukosis C0085165
img Leukemia, Plasma Cell C0023484
img Leukemia, Feline C0085164
Ancestral Roots
RootRoot Plus OneDepthParent
img Neoplasms C0027651img Neoplasms by Histologic Type C00276523img Neoplasms by Histologic Type C0027652
Relationships (410)

Relation Types:
diso_​to_​anat : 31
diso_​to_​chem : 131
diso_​to_​diso : 164
diso_​to_​gene : 49
diso_​to_​phen : 3
diso_​to_​phys : 32


Relationships:
none : 214
allele_​associated_​with_​disease : 1
classified_​as : 83
gene_​associated_​with_​disease : 46
gene_​product_​malfunction_​associated_​with_​disease : 2
is_​abnormal_​cell_​of_​disease : 3
is_​normal_​cell_​origin_​of_​disease : 1
is_​normal_​tissue_​origin_​of_​disease : 1
is_​not_​finding_​of_​disease : 1
is_​primary_​anatomic_​site_​of_​disease : 1
isa : 15
location_​of : 1
mapped_​to : 3
may_​treat : 30
permuted_​term_​of : 1
related_​to : 4
use : 3
Page Size
Current 25
  Page 1 of 17
Prior Page
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Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_PHEN848img genetic aspects C0017399
DISO_to_PHEN673img genetic aspects C0017399
DISO_to_CHEM287img Antineoplastic Agents C0003392
DISO_to_DISO274img Lymphoma C0024299
DISO_to_DISO255img Lymphoma C0024299
DISO_to_PHYS237img Apoptosis C0162638
DISO_to_DISO205img Complication Aspects C1171258
DISO_to_DISO201img Complication Aspects C1171258
DISO_to_CHEM195img Antineoplastic Agents C0003392
DISO_to_PHYS183img Apoptosis C0162638
DISO_to_ANAT119img In Blood C0005768
DISO_to_ANAT108img In Blood C0005768
DISO_to_DISO82img chemically induced C0007994
DISO_to_CHEM80img Chimeric Oncogene Proteins C0029014
DISO_to_DISO79img chemically induced C0007994
DISO_to_CHEM77img Binding Protein, DNA C0012940
DISO_to_PHYS76img GENE EXPRESSION REG LEUKEMIC C0017267
DISO_to_PHYS75img ANTINEOPL AGENT RESISTANCE C0282588
DISO_to_CHEM74img TRANSCRIPTION FACTOR C0040648
DISO_to_CHEM70img Acute Lymphoblastic Leukemia Protein 1 C1571619
DISO_to_DISO70img Myelodysplastic Syndromes C0026986
DISO_to_ANAT69img Cell, Neoplastic Stem C1956421
DISO_to_ANAT68img Hematopoietic Stem Cells C0018956
DISO_to_DISO67img CELL TRANSFORM NEOPL C0007621
DISO_to_DISO66img Dysmyelopoietic Syndromes C0026986
Genes (1590)

Species:
human : 1524
mouse : 66
Page Size
Current 25
  Page 1 of 64
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
MousePAOX196743polyamine oxidase (exo-N4-amino)
img NCI, Score=801, Pubmed Id: 2495754, UMLKSK CUI: C0023418
img NCI, Score=801, Pubmed Id: 1988107, UMLKSK CUI: C0023418
MouseCLNK116449cytokine-dependent hematopoietic cell linker
img NCI, Score=801, Pubmed Id: 15199160, UMLKSK CUI: C0023418
MousePRDM1663976PR domain containing 16
img NCI, Score=801, Pubmed Id: 16109773, UMLKSK CUI: C0023418
MouseGAS560674growth arrest-specific 5 (non-protein coding)
img NCI, Score=801, Pubmed Id: 1630459, UMLKSK CUI: C0023418
MouseSMOX54498spermine oxidase
img NCI, Score=801, Pubmed Id: 2495754, UMLKSK CUI: C0023418
img NCI, Score=801, Pubmed Id: 1988107, UMLKSK CUI: C0023418
MouseGPR13229933G protein-coupled receptor 132
img NCI, Score=801, Pubmed Id: 12086852, UMLKSK CUI: C0023418
MouseBLNK29760B-cell linker
img NCI, Score=801, Pubmed Id: 15549729, UMLKSK CUI: C0023418
MouseAFF427125AF4/FMR2 family, member 4
img NCI, Score=801, Pubmed Id: 16024815, UMLKSK CUI: C0023418
MouseLAT27040linker for activation of T cells
img NCI, Score=801, Pubmed Id: 15549729, UMLKSK CUI: C0023418
MouseKLF110661Kruppel-like factor 1 (erythroid)
img NCI, Score=801, Pubmed Id: 10468560, UMLKSK CUI: C0023418
MouseMRVI110335murine retrovirus integration site 1 homolog
img NCI, Score=801, Pubmed Id: 10321731, UMLKSK CUI: C0023418
img NCI, Score=801, Pubmed Id: 10321731, UMLKSK CUI: C0023418
MouseSOCS39021suppressor of cytokine signaling 3
img NCI, Score=801, Pubmed Id: 9811457, UMLKSK CUI: C0023418
MouseCCNA18900cyclin A1
img NCI, Score=801, Pubmed Id: 15829981, UMLKSK CUI: C0023418
img NCI, Score=801, Pubmed Id: 12536081, UMLKSK CUI: C0023418
MouseTCL1A8115T-cell leukemia/lymphoma 1A
img NCI, Score=801, Pubmed Id: 9520462, UMLKSK CUI: C0023418
img NCI, Score=801, Pubmed Id: 9520462, UMLKSK CUI: C0023418
MouseMLLT108028myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
img NCI, Score=801, Pubmed Id: 17097559, UMLKSK CUI: C0023418
img NCI, Score=801, Pubmed Id: 17329976, UMLKSK CUI: C0023418
MouseTYK27297tyrosine kinase 2
img NCI, Score=801, Pubmed Id: 15578097, UMLKSK CUI: C0023418
MouseTEC7006transient erythroblastopenia of childhood
img NCI, Score=801, Pubmed Id: 11358387, UMLKSK CUI: C0023418
MouseTCF126938transcription factor 12
Click here to display 3 evidence detail records.
MouseTAL16886T-cell acute lymphocytic leukemia 1
img NCI, Score=801, Pubmed Id: 7718483, UMLKSK CUI: C0023418
MouseSTAT5B6777signal transducer and activator of transcription 5B
Click here to display 4 evidence detail records.
MouseSTAT36774signal transducer and activator of transcription 3 (acute-phase response factor)
img NCI, Score=801, Pubmed Id: 12444555, UMLKSK CUI: C0023418
MouseST146768suppression of tumorigenicity 14 (colon carcinoma)
img NCI, Score=801, Pubmed Id: 10199918, UMLKSK CUI: C0023418
MouseSRM6723spermidine synthase
img NCI, Score=801, Pubmed Id: 7116328, UMLKSK CUI: C0023418
img NCI, Score=801, Pubmed Id: 7116328, UMLKSK CUI: C0023418
MouseSPI16688spleen focus forming virus (SFFV) proviral integration oncogene
img NCI, Score=801, Pubmed Id: 16113082, UMLKSK CUI: C0023418
img NCI, Score=801, Pubmed Id: 9354675, UMLKSK CUI: C0023418
MousePTPN115781protein tyrosine phosphatase, non-receptor type 11
img NCI, Score=801, Pubmed Id: 15710330, UMLKSK CUI: C0023418
img NCI, Score=801, Pubmed Id: 15710330, UMLKSK CUI: C0023418
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0023418Leukemia0self