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Details
Link-It Detail - Disease - Leprosy
Debug Stats
  • ### Total Build Time: 279 ms 51.181 KB
  • CONCEPT_NAME gt=5 ms Completed: 5 ms rowSize= 312 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 375 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 560 bytes
  • CONCEPT_CHILDREN gt=10 ms Completed: 10 ms rowSize= 1,002 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.523 KB
  • CONCEPT_RELATIONSHIPS gt=234 ms Completed: 234 ms rowSize= 13.548 KB
  • CONCEPT_GENES gt=27 ms Completed: 27 ms rowSize= 32.561 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.142 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Leprosy C0023343
Definition (1)
A bacterial granulomatous infection caused by Mycobacterium leprae. It is a progressive disease affecting the skin, peripheral nerves, and limbs. If untreated, it causes permanent tissue damage leading to autoamputations.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (1)
img Mycobacterium Infections C0026918
Children (2)
img Leprosy, Multibacillary C1562585
img Leprosy, Paucibacillary C1562908
Ancestral Roots
RootRoot Plus OneDepthParent
img Bacterial Infections and Mycoses C0004615img Bacterial Infections C00046236img Mycobacterium Infections C0026918
Relationships (82)

Relation Types:
diso_​to_​anat : 7
diso_​to_​chem : 33
diso_​to_​diso : 33
diso_​to_​gene : 1
diso_​to_​phen : 2
diso_​to_​phys : 6


Relationships:
none : 53
classifies : 1
isa : 11
location_​of : 2
mapped_​to : 6
may_​treat : 9
Page Size
Current 25
  Page 1 of 4
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO204img Complication Aspects C1171258
DISO_to_DISO156img Complication Aspects C1171258
DISO_to_CHEM127img Agents, Antileprotic C0023342
DISO_to_CHEM94img Agents, Antileprotic C0023342
DISO_to_PHEN80img genetic aspects C0017399
DISO_to_PHEN49img genetic aspects C0017399
DISO_to_CHEM48img ANTIGENS BACT C0003321
DISO_to_DISO47img Peripheral Nervous System Diseases C0031117
DISO_to_CHEM36img ANTIBODIES BACT C0003244
DISO_to_ANAT34img Skin C1123023
DISO_to_DISO33img Peripheral Nervous System Diseases C0031117
DISO_to_ANAT32img Skin C1123023
DISO_to_ANAT29img In Blood C0005768
DISO_to_DISO29img HIV Infections C0019693
DISO_to_CHEM27img Glycolipid C0017950
DISO_to_CHEM27img Glycolipids C0017950
DISO_to_DISO27img Disease, Endemic C0277550
DISO_to_PHYS27img GENET PREDISPOSITION C0314657
DISO_to_PHYS25img GENET PREDISPOSITION C0314657
DISO_to_GENE23img Polymorphism, Single Nucleotide C0752046
DISO_to_DISO20img Tuberculosis C0041296
DISO_to_CHEM18img ANTIGENS BACT C0003321
DISO_to_CHEM18img Rifampin C0035608
DISO_to_DISO18img Disease, Endemic C0277550
DISO_to_CHEM17img BACT DNA C0012924
Genes (22)

Species:
human : 22
SpeciesGeneGeneIdGene NameEvidence
HumanLOC100507436100507436
img GENERIF, Score=694, Pubmed Id: 16923796, UMLKSK CUI: C0023343
HumanPACRG135138PARK2 co-regulated
img GAD, Score=1000, Pubmed Id: 16391553, UMLKSK CUI: C0023343
img GENERIF, Score=1000, Pubmed Id: 14737177, UMLKSK CUI: C0023343
img GAD, Score=1000, Pubmed Id: 14737177, UMLKSK CUI: C0023343
HumanBTNL256244butyrophilin-like 2 (MHC class II associated)
img GENERIF, Score=1000, Pubmed Id: 17493147, UMLKSK CUI: C0023343
HumanCD20930835CD209 molecule
img GENERIF, Score=861, Pubmed Id: 15880118, UMLKSK CUI: C0023343
HumanVDR7421vitamin D (1,25- dihydroxyvitamin D3) receptor
img GAD, Score=666, Pubmed Id: 9841838, UMLKSK CUI: C0023343
HumanTNF7124tumor necrosis factor
img GAD, Score=1000, Pubmed Id: 12486602, UMLKSK CUI: C0023343
HumanTLR27097toll-like receptor 2
img GENERIF, Score=861, Pubmed Id: 12646604, UMLKSK CUI: C0023343
img OMIM, Score=770, UMLKSK CUI: C0023343
img GAD, Score=1000, Pubmed Id: 15726416, UMLKSK CUI: C0023343
HumanTLR17096toll-like receptor 1
img OMIM, Score=770, UMLKSK CUI: C0023343
HumanSLC11A16556solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
img GAD, Score=666, Pubmed Id: 11791966, UMLKSK CUI: C0023343
img GAD, Score=1000, Pubmed Id: 11791966, UMLKSK CUI: C0023343
img GENERIF, Score=1000, Pubmed Id: 17955444, UMLKSK CUI: C0023343
img GAD, Score=1000, Pubmed Id: 12486602, UMLKSK CUI: C0023343
img GENERIF, Score=1000, Pubmed Id: 15755200, UMLKSK CUI: C0023343
HumanSLAMF16504signaling lymphocytic activation molecule family member 1
img GENERIF, Score=1000, Pubmed Id: 15356162, UMLKSK CUI: C0023343
HumanCCL116356chemokine (C-C motif) ligand 11
img GENERIF, Score=694, Pubmed Id: 17827376, UMLKSK CUI: C0023343
HumanPARK25071parkinson protein 2, E3 ubiquitin protein ligase (parkin)
img GAD, Score=1000, Pubmed Id: 14737177, UMLKSK CUI: C0023343
img GENERIF, Score=1000, Pubmed Id: 14737177, UMLKSK CUI: C0023343
img GAD, Score=1000, Pubmed Id: 16391553, UMLKSK CUI: C0023343
HumanNINJ14814ninjurin 1
img GENERIF, Score=1000, Pubmed Id: 17825431, UMLKSK CUI: C0023343
HumanMBL24153mannose-binding lectin (protein C) 2, soluble
img GENERIF, Score=1000, Pubmed Id: 17922403, UMLKSK CUI: C0023343
HumanLTA4049lymphotoxin alpha
img GENERIF, Score=827, Pubmed Id: 17353895, UMLKSK CUI: C0023343
img GAD, Score=1000, Pubmed Id: 12486602, UMLKSK CUI: C0023343
HumanLAMA23908laminin, alpha 2
img GAD, Score=1000, Pubmed Id: 12100448, UMLKSK CUI: C0023343
HumanIL12RB23595interleukin 12 receptor, beta 2
img GAD, Score=1000, Pubmed Id: 15976343, UMLKSK CUI: C0023343
HumanIL12RB13594interleukin 12 receptor, beta 1
img GAD, Score=1000, Pubmed Id: 12743658, UMLKSK CUI: C0023343
HumanIL12B3593interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
img GENERIF, Score=1000, Pubmed Id: 17445208, UMLKSK CUI: C0023343
HumanIL103586interleukin 10
img GENERIF, Score=694, Pubmed Id: 15306847, UMLKSK CUI: C0023343
HumanHLA-DRB13123
img GENERIF, Score=1000, Pubmed Id: 17396103, UMLKSK CUI: C0023343
HumanHLA-A3105
img GENERIF, Score=694, Pubmed Id: 15072129, UMLKSK CUI: C0023343
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0023343Leprosy0self