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Details
Link-It Detail - Disease - Leishmaniasis
Debug Stats
  • ### Total Build Time: 354 ms 38.443 KB
  • CONCEPT_NAME gt=6 ms Completed: 6 ms rowSize= 324 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 1.135 KB
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=15 ms Completed: 15 ms rowSize= 999 bytes
  • CONCEPT_CHILDREN gt=9 ms Completed: 9 ms rowSize= 1,003 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=42 ms Completed: 42 ms rowSize= 5.351 KB
  • CONCEPT_RELATIONSHIPS gt=250 ms Completed: 250 ms rowSize= 13.390 KB
  • CONCEPT_GENES gt=26 ms Completed: 26 ms rowSize= 14.938 KB
  • CONCEPT_XREFS gt=4 ms Completed: 4 ms rowSize= 1.147 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Leishmaniasis C0023281
Definition (1)

Leishmaniasis is a parasitic disease spread by the bite of infected sand flies. There are several different forms of leishmaniasis. The most common are cutaneous and visceral. The cutaneous type causes skin sores. The visceral type affects internal organs such as the spleen, liver and bone marrow. People with this form usually have fever, weight loss and an enlarged spleen and liver.

Leishmaniasis is found in parts of about 88 countries. Most of these countries are in the tropics and subtropics. It is possible but very unlikely that you would get this disease in the United States. But you should be aware of it if you are traveling to the Middle East or parts of Central America, South American, Asia, Africa or southern Europe.

The best way to prevent the disease is to protect yourself from sand fly bites. If not treated, leishmaniasis can be serious. Visceral disease can be deadly.

Centers for Disease Control and Prevention

Semantic Types (1)
Disease or Syndrome (T047)
Parents (2)
img Skin Diseases, Parasitic C0037280
img Euglenozoa Infections C2717956
Children (2)
img Leishmaniasis, Cutaneous C0023283
img Leishmaniasis, Visceral C0023290
Ancestral Roots
RootRoot Plus OneDepthParent
img Parasitic Diseases C0030499img Skin Diseases, Parasitic C00372803img Skin Diseases, Parasitic C0037280
img Skin and Connective Tissue Diseases C0175166img Skin Diseases C00372745img Skin Diseases, Parasitic C0037280
img Bacterial Infections and Mycoses C0004615img Infection C00213115img Skin Diseases, Parasitic C0037280
img Parasitic Diseases C0030499img Protozoan Infections C00337404img Euglenozoa Infections C2717956
Relationships (78)

Relation Types:
diso_​to_​anat : 6
diso_​to_​chem : 35
diso_​to_​diso : 32
diso_​to_​phen : 5


Relationships:
none : 47
classifies : 1
expanded_​form_​of : 1
isa : 8
mapped_​to : 7
may_​treat : 13
related_​to : 1
Page Size
Current 25
  Page 1 of 4
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO117img Dog Diseases C0012979
DISO_to_CHEM88img Antiprotozoal Agents C0003416
DISO_to_DISO55img CANINE DIS C0012979
DISO_to_CHEM50img ANTIPROTOZOALS C0003416
DISO_to_DISO38img Complication Aspects C1171258
DISO_to_CHEM31img Leishmaniasis Vaccine C1548483
DISO_to_DISO29img Complication Aspects C1171258
DISO_to_ANAT27img In Blood C0005768
DISO_to_CHEM22img Antibodies, Protozoan C0003252
DISO_to_CHEM21img Plant Extracts C0032081
DISO_to_CHEM20img Protozoan Vaccines C0080067
DISO_to_CHEM19img Antigens, Protozoan C0003338
DISO_to_ANAT17img Macrophages C0024432
DISO_to_CHEM15img Antigens, Protozoan C0003338
DISO_to_DISO15img Chagas Disease C0041234
DISO_to_CHEM14img Chloride, Choline Phosphate C0031716
DISO_to_CHEM14img Phosphorylcholine C0031716
DISO_to_DISO14img Trypanosomiasis C0041227
DISO_to_CHEM13img DNA, Protozoan C0079250
DISO_to_CHEM13img Organometallic Compounds C0029252
DISO_to_DISO13img Cat Diseases C0007350
DISO_to_DISO13img HIV Infections C0019693
DISO_to_PHEN13img genetic aspects C0017399
DISO_to_CHEM12img Agents, Trypanocidal C0041214
DISO_to_ANAT11img Dendritic Cells C0011306
Genes (18)

Species:
human : 18
SpeciesGeneGeneIdGene NameEvidence
HumanFOXP350943forkhead box P3
INFERRED, Score=800, UMLKSK CUI: C0023281
HumanTNF7124tumor necrosis factor
INFERRED, Score=800, UMLKSK CUI: C0023281
HumanTGFB17040transforming growth factor, beta 1
INFERRED, Score=800, UMLKSK CUI: C0023281
HumanSLC11A16556solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
INFERRED, Score=800, UMLKSK CUI: C0023281
HumanNOS24843nitric oxide synthase 2, inducible
INFERRED, Score=800, UMLKSK CUI: C0023281
HumanMBL24153mannose-binding lectin (protein C) 2, soluble
INFERRED, Score=800, UMLKSK CUI: C0023281
HumanIL153600interleukin 15
INFERRED, Score=800, UMLKSK CUI: C0023281
HumanIL103586interleukin 10
img GENERIF, Score=694, Pubmed Id: 16364177, UMLKSK CUI: C0023281
HumanIL2RB3560interleukin 2 receptor, beta
INFERRED, Score=800, UMLKSK CUI: C0023281
HumanIL2RA3559interleukin 2 receptor, alpha
INFERRED, Score=800, UMLKSK CUI: C0023281
HumanIFNGR13459interferon gamma receptor 1
INFERRED, Score=800, UMLKSK CUI: C0023281
HumanIFNG3458interferon, gamma
img GENERIF, Score=1000, Pubmed Id: 17456233, UMLKSK CUI: C0023281
HumanHLA-DQB13119
img GAD, Score=1000, Pubmed Id: 15041165, UMLKSK CUI: C0023281
HumanHLA-DQA13117
img GAD, Score=1000, Pubmed Id: 15041165, UMLKSK CUI: C0023281
HumanHLA-DPB13115
img GAD, Score=1000, Pubmed Id: 15041165, UMLKSK CUI: C0023281
HumanHLA-DPA13113
img GAD, Score=1000, Pubmed Id: 15041165, UMLKSK CUI: C0023281
HumanFASLG356Fas ligand (TNF superfamily, member 6)
INFERRED, Score=800, UMLKSK CUI: C0023281
HumanFAS355Fas cell surface death receptor
INFERRED, Score=800, UMLKSK CUI: C0023281
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0023281Leishmaniasis0self