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Details
Link-It Detail - Disease - Inappropriate ADH Syndrome
Debug Stats
  • ### Total Build Time: 129 ms 22.913 KB
  • CONCEPT_NAME gt=8 ms Completed: 8 ms rowSize= 350 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 636 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=11 ms Completed: 11 ms rowSize= 999 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=28 ms Completed: 28 ms rowSize= 4.087 KB
  • CONCEPT_RELATIONSHIPS gt=65 ms Completed: 65 ms rowSize= 12.996 KB
  • CONCEPT_GENES gt=8 ms Completed: 8 ms rowSize= 2.513 KB
  • CONCEPT_XREFS gt=7 ms Completed: 7 ms rowSize= 1.160 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Inappropriate ADH Syndrome C0021141
Definition (1)
A condition of HYPONATREMIA and renal salt loss attributed to overexpansion of BODY FLUIDS resulting from sustained release of ANTIDIURETIC HORMONES which stimulates renal resorption of water. It is characterized by normal KIDNEY function, high urine OSMOLALITY, low serum osmolality, and neurological dysfunction. Etiologies include ADH-producing neoplasms, injuries or diseases involving the HYPOTHALAMUS, the PITUITARY GLAND, and the LUNG. This syndrome can also be drug-induced.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (2)
img Pituitary Diseases C0032002
img Water-Electrolyte Imbalance C0043065
Ancestral Roots
RootRoot Plus OneDepthParent
img Nervous System Diseases C0027765img Central Nervous System Diseases C00076826img Pituitary Diseases C0032002
img Endocrine System Diseases C0014130img Pituitary Diseases C00320023img Pituitary Diseases C0032002
img Nutritional and Metabolic Diseases C0028715img Metabolic Diseases C00255174img Water-Electrolyte Imbalance C0043065
Relationships (44)

Relation Types:
diso_​to_​anat : 3
diso_​to_​chem : 22
diso_​to_​diso : 18
diso_​to_​phen : 1


Relationships:
none : 34
entry_​version_​of : 1
is_​primary_​anatomic_​site_​of_​disease : 1
isa : 1
mapped_​to : 1
may_​treat : 6
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO97img Hyponatremia C0020625
DISO_to_DISO75img Hyponatremia C0020625
DISO_to_DISO72img Complication Aspects C1171258
DISO_to_DISO64img chemically induced C0007994
DISO_to_DISO47img chemically induced C0007994
DISO_to_DISO46img Complication Aspects C1171258
DISO_to_CHEM25img Receptors, Vasopressin C0078077
DISO_to_ANAT24img In Blood C0005768
DISO_to_CHEM24img Benzazepine C0005034
DISO_to_CHEM19img Serotonin Uptake Inhibitors C0162758
DISO_to_ANAT15img In Blood C0005768
DISO_to_CHEM14img Serotonin Uptake Inhibitors C0162758
DISO_to_DISO11img Lung Neoplasms C0024121
DISO_to_CHEM10img Sodium C0037473
DISO_to_DISO10img Lung Neoplasms C0024121
DISO_to_DISO9img Carcinoma, Small Cell C0262584
DISO_to_PHEN9img genetic aspects C0017399
DISO_to_CHEM8img 1,3-Dihydro-1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-5-isobenzofurancarbonitrile C0008845
DISO_to_CHEM7img Agents, Second-Generation Antidepressive C0242905
DISO_to_CHEM7img Arginine Vasopressin C0003779
DISO_to_CHEM7img Vasopressins C0042413
DISO_to_DISO7img PARANEOPL SYNDROMES C0030472
DISO_to_DISO7img Pituitary Neoplasms C0032019
DISO_to_CHEM6img (-)-(3S,4R)-4-(p-Fluorophenyl)-3-((3,4-(methylenedioxy)phenoxy)methyl)piperidine C0070122
DISO_to_CHEM6img ANTIPSYCHOTICS C0040615
Genes (2)

Species:
human : 2
SpeciesGeneGeneIdGene NameEvidence
HumanIL63569interleukin 6 (interferon, beta 2)
img GENERIF, Score=1000, Pubmed Id: 12585340, UMLKSK CUI: C0021141
HumanHMBS3145hydroxymethylbilane synthase
img OMIM, Score=1000, UMLKSK CUI: C0021141
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0021141Inappropriate ADH Syndrome0self