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Details
Link-It Detail - Disease - Immune System Diseases
Debug Stats
  • ### Total Build Time: 425 ms 39.382 KB
  • CONCEPT_NAME gt=7 ms Completed: 7 ms rowSize= 342 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 1.142 KB
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=2 ms Completed: 2 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 7 bytes
  • CONCEPT_CHILDREN gt=6 ms Completed: 6 ms rowSize= 4.042 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 15 bytes
  • CONCEPT_RELATIONSHIPS gt=136 ms Completed: 136 ms rowSize= 13.912 KB
  • CONCEPT_GENES gt=272 ms Completed: 272 ms rowSize= 18.563 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.156 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Immune System Diseases C0021053
Definition (1)

When your body encounters a germ, its first line of defense is your immune system. Specialized cells and organs help your body recognize and respond to foreign invaders. Your immune system even has its own circulatory system, called the lymphatic system.

If your immune system cannot do its job, the results can be serious. Disorders of the immune system include

  • Allergy and asthma - inappropriate immune responses to substances that are usually harmless
  • Graft-vs.-host disease - a life-threatening reaction in people receiving organ transplants
  • Immune deficiency diseases - disorders in which your resistance to disease becomes dangerously low
  • Autoimmune diseases - diseases causing your immune system to attack your own body's cells and tissues by mistake
Semantic Types (1)
Disease or Syndrome (T047)
Children (9)
img Immunologic Deficiency Syndromes C0021051
img Purpura, Thrombocytopenic C0857305
img Hypersensitivity C0020517
img Immunoproliferative Disorders C0021070
img Autoimmune Diseases C0004364
img Graft vs Host Disease C0018133
img Glomerulonephritis, Membranoproliferative C0017662
img Immune Reconstitution Inflammatory Syndrome C1619738
img Blood Group Incompatibility C0005806
Relationships (86)

Relation Types:
diso_​to_​anat : 10
diso_​to_​chem : 13
diso_​to_​diso : 53
diso_​to_​phen : 2
diso_​to_​phys : 8


Relationships:
none : 56
associated_​with : 2
classified_​as : 16
isa : 5
mapped_​to : 3
may_​diagnose : 1
permuted_​term_​of : 1
related_​to : 1
used_​for : 1
Page Size
Current 25
  Page 1 of 4
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_PHEN70img genetic aspects C0017399
DISO_to_DISO62img Complication Aspects C1171258
DISO_to_DISO38img chemically induced C0007994
DISO_to_PHEN36img genetic aspects C0017399
DISO_to_DISO35img Complication Aspects C1171258
DISO_to_DISO32img Inflammation C0021368
DISO_to_ANAT31img Immune System C0020962
DISO_to_ANAT26img Immune System C0020962
DISO_to_DISO19img Neoplasms C0027651
DISO_to_DISO18img Hypersensitivity C0020517
DISO_to_DISO18img chemically induced C0007994
DISO_to_DISO17img Inflammation C0021368
DISO_to_DISO17img Neoplasms C0027651
DISO_to_ANAT16img In Blood C0005768
DISO_to_CHEM15img Immunologic Factors C0021054
DISO_to_DISO15img HIV Infections C0019693
DISO_to_ANAT14img Regulatory T-Lymphocytes C0039198
DISO_to_CHEM14img Antibodies, Monoclonal C0003250
DISO_to_PHYS14img Immune state C0020964
DISO_to_DISO13img Nervous System Diseases C0027765
DISO_to_ANAT12img T-Lymphocyte C0039194
DISO_to_PHYS12img Immune state C0020964
DISO_to_CHEM11img Cytokines C0079189
DISO_to_DISO11img Communicable Diseases C0009450
DISO_to_DISO11img Hypersensitivity C0020517
Genes (2209)

Species:
human : 2209
Page Size
Current 25
  Page 1 of 89
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanLOC100507436100507436
INFERRED, Score=800, UMLKSK CUI: C0021053
HumanSLEB5100188798Systemic lupus erythematosus, susceptibility to, 5
INFERRED, Score=800, UMLKSK CUI: C0021053
HumanCD24100133941CD24 molecule
INFERRED, Score=800, UMLKSK CUI: C0021053
HumanLOC100133284100133284striatin, calmodulin binding protein pseudogene
INFERRED, Score=800, UMLKSK CUI: C0021053
HumanKIR2DS2100132285killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
INFERRED, Score=800, UMLKSK CUI: C0021053
HumanCTAGE4100128553CTAGE family, member 4
INFERRED, Score=800, UMLKSK CUI: C0021053
HumanCCR2729230chemokine (C-C motif) receptor 2
INFERRED, Score=800, UMLKSK CUI: C0021053
HumanSPANXB1728695SPANX family, member B1
INFERRED, Score=800, UMLKSK CUI: C0021053
HumanCSAG2728461CSAG family, member 2
INFERRED, Score=800, UMLKSK CUI: C0021053
HumanGGT2728441gamma-glutamyltransferase 2
INFERRED, Score=800, UMLKSK CUI: C0021053
HumanPPBPL1728045
INFERRED, Score=800, UMLKSK CUI: C0021053
HumanMUC5B727897mucin 5B, oligomeric mucus/gel-forming
INFERRED, Score=800, UMLKSK CUI: C0021053
HumanSFTPA1653509surfactant protein A1
INFERRED, Score=800, UMLKSK CUI: C0021053
HumanNCF1653361neutrophil cytosolic factor 1
INFERRED, Score=800, UMLKSK CUI: C0021053
HumanNOS2P1645740nitric oxide synthase 2 pseudogene 1
INFERRED, Score=800, UMLKSK CUI: C0021053
HumanLOC644165644165
INFERRED, Score=800, UMLKSK CUI: C0021053
HumanNPS594857neuropeptide S
INFERRED, Score=800, UMLKSK CUI: C0021053
HumanCLLU1574028chronic lymphocytic leukemia up-regulated 1
INFERRED, Score=800, UMLKSK CUI: C0021053
HumanERVK7449619
INFERRED, Score=800, UMLKSK CUI: C0021053
HumanASTL431705astacin-like metallo-endopeptidase (M12 family)
INFERRED, Score=800, UMLKSK CUI: C0021053
HumanMIR17HG407975miR-17-92 cluster host gene (non-protein coding)
INFERRED, Score=800, UMLKSK CUI: C0021053
HumanMIR181B2406956microRNA 181b-2
INFERRED, Score=800, UMLKSK CUI: C0021053
HumanMIR181B1406955microRNA 181b-1
INFERRED, Score=800, UMLKSK CUI: C0021053
HumanMIR181A2406954microRNA 181a-2
INFERRED, Score=800, UMLKSK CUI: C0021053
HumanMIR17406952microRNA 17
INFERRED, Score=800, UMLKSK CUI: C0021053
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0021053Immune System Diseases0self