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Details
Link-It Detail - Disease - Immune Complex Diseases
Debug Stats
  • ### Total Build Time: 102 ms 27.280 KB
  • CONCEPT_NAME gt=8 ms Completed: 8 ms rowSize= 344 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 541 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=15 ms Completed: 15 ms rowSize= 552 bytes
  • CONCEPT_CHILDREN gt=14 ms Completed: 14 ms rowSize= 1.843 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.502 KB
  • CONCEPT_RELATIONSHIPS gt=29 ms Completed: 29 ms rowSize= 6.812 KB
  • CONCEPT_GENES gt=33 ms Completed: 33 ms rowSize= 14.353 KB
  • CONCEPT_XREFS gt=3 ms Completed: 3 ms rowSize= 1.157 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Immune Complex Diseases C0020951
Definition (1)
Group of diseases mediated by the deposition of large soluble complexes of antigen and antibody with resultant damage to tissue. Besides SERUM SICKNESS and the ARTHUS REACTION, evidence supports a pathogenic role for immune complexes in many other IMMUNE SYSTEM DISEASES including GLOMERULONEPHRITIS, systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC) and POLYARTERITIS NODOSA.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (1)
img Hypersensitivity C0020517
Children (4)
img Purpura, Schoenlein-Henoch C0034152
img Arthus Reaction C0003907
img Serum Sickness C0036830
img Vasculitis, Leukocytoclastic, Cutaneous C0151436
Ancestral Roots
RootRoot Plus OneDepthParent
img Immune System Diseases C0021053img Hypersensitivity C00205173img Hypersensitivity C0020517
Relationships (15)

Relation Types:
diso_​to_​anat : 3
diso_​to_​chem : 3
diso_​to_​diso : 7
diso_​to_​phen : 2


Relationships:
none : 13
permuted_​term_​of : 1
use : 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO16img Glomerulonephritis C0017658
DISO_to_DISO14img Glomerulonephritis C0017658
DISO_to_DISO9img Complication Aspects C1171258
DISO_to_PHEN8img genetic aspects C0017399
DISO_to_CHEM7img Antigen-Antibody Complex C0003313
DISO_to_CHEM6img Antigen-Antibody Complex C0003313
DISO_to_PHEN6img genetic aspects C0017399
DISO_to_ANAT5img Kidney C0022646
DISO_to_CHEM5img Immunoglobulin G C0020852
DISO_to_ANAT4img In Blood C0005768
DISO_to_ANAT4img Kidney Glomerulus C0022663
DISO_to_DISO4img Glomerulonephritis, Membranoproliferative C0017662
DISO_to_DISO4img Kidney Diseases C0022658
DISO_to_DISOpermuted_term_ofimg Immune Complex Diseases C0020951
DISO_to_DISOuseimg immune inclusion disease C0598653
Genes (23)

Species:
human : 23
SpeciesGeneGeneIdGene NameEvidence
HumanPTPN2226191protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
INFERRED, Score=800, UMLKSK CUI: C0020951
HumanTNFSF13B10673tumor necrosis factor (ligand) superfamily, member 13b
img GENERIF, Score=911, Pubmed Id: 18606652, UMLKSK CUI: C0020951
HumanNPHS27827nephrosis 2, idiopathic, steroid-resistant (podocin)
INFERRED, Score=800, UMLKSK CUI: C0020951
HumanSCGB1A17356secretoglobin, family 1A, member 1 (uteroglobin)
INFERRED, Score=800, UMLKSK CUI: C0020951
HumanSELL6402selectin L
INFERRED, Score=800, UMLKSK CUI: C0020951
HumanSELE6401selectin E
INFERRED, Score=800, UMLKSK CUI: C0020951
HumanPON15444paraoxonase 1
INFERRED, Score=800, UMLKSK CUI: C0020951
HumanPIGR5284polymeric immunoglobulin receptor
INFERRED, Score=800, UMLKSK CUI: C0020951
HumanNOS34846nitric oxide synthase 3 (endothelial cell)
INFERRED, Score=800, UMLKSK CUI: C0020951
HumanNOS24843nitric oxide synthase 2, inducible
INFERRED, Score=800, UMLKSK CUI: C0020951
HumanMMP94318matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
INFERRED, Score=800, UMLKSK CUI: C0020951
HumanMET4233met proto-oncogene
INFERRED, Score=800, UMLKSK CUI: C0020951
HumanIL63569interleukin 6 (interferon, beta 2)
INFERRED, Score=800, UMLKSK CUI: C0020951
HumanIL1B3553interleukin 1, beta
INFERRED, Score=800, UMLKSK CUI: C0020951
HumanHLA-DRB13123
INFERRED, Score=800, UMLKSK CUI: C0020951
HumanHLA-DQA13117
INFERRED, Score=800, UMLKSK CUI: C0020951
HumanHLA-B3106
INFERRED, Score=800, UMLKSK CUI: C0020951
HumanCTLA41493cytotoxic T-lymphocyte-associated protein 4
INFERRED, Score=800, UMLKSK CUI: C0020951
HumanCP1356ceruloplasmin (ferroxidase)
INFERRED, Score=800, UMLKSK CUI: C0020951
HumanCAT847catalase
INFERRED, Score=800, UMLKSK CUI: C0020951
HumanC4B721complement component 4B (Chido blood group)
INFERRED, Score=800, UMLKSK CUI: C0020951
HumanAGT183angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
INFERRED, Score=800, UMLKSK CUI: C0020951
HumanADM133adrenomedullin
INFERRED, Score=800, UMLKSK CUI: C0020951
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0020951Immune Complex Diseases0self