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Details
Link-It Detail - Disease - Hypokalemia
Debug Stats
  • [ From Cache ]
  • ### Total Build Time: 33 ms 81.499 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 320 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 582 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 232 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 563 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.526 KB
  • CONCEPT_RELATIONSHIPS gt=4 ms Completed: 4 ms rowSize= 56.348 KB
  • CONCEPT_GENES gt=21 ms Completed: 21 ms rowSize= 20.787 KB
  • CONCEPT_XREFS gt=8 ms Completed: 8 ms rowSize= 1.146 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Hypokalemia C0020621
Definition (1)
Abnormally low potassium concentration in the blood. It may result from potassium loss by renal secretion or by the gastrointestinal route, as by vomiting or diarrhea. It may be manifested clinically by neuromuscular disorders ranging from weakness to paralysis, by electrocardiographic abnormalities (depression of the T wave and elevation of the U wave), by renal disease, and by gastrointestinal disorders. (Dorland, 27th ed)
Semantic Types (2)
Disease or Syndrome (T047)
Finding (T033)
Parents (1)
img Water-Electrolyte Imbalance C0043065
Ancestral Roots
RootRoot Plus OneDepthParent
img Nutritional and Metabolic Diseases C0028715img Metabolic Diseases C00255174img Water-Electrolyte Imbalance C0043065
Relationships (151)

Relation Types:
diso_​to_​anat : 2
diso_​to_​chem : 93
diso_​to_​diso : 52
diso_​to_​phen : 4


Relationships:
none : 49
associated_​with : 1
classifies : 1
disease_​has_​finding : 3
isa : 4
mapped_​to : 12
may_​prevent : 37
may_​treat : 44
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO117img chemically induced C0007994
DISO_to_DISO106img Complication Aspects C1171258
DISO_to_DISO83img Complication Aspects C1171258
DISO_to_DISO68img chemically induced C0007994
DISO_to_ANAT60img In Blood C0005768
DISO_to_CHEM53img Potassium C0032821
DISO_to_DISO53img Hypertension C0020538
DISO_to_DISO39img ALKALOSIS C0002063
DISO_to_DISO36img Hypertension C0020538
DISO_to_PHEN34img genetic aspects C0017399
DISO_to_ANAT29img In Blood C0005768
DISO_to_CHEM26img Potassium C0032821
DISO_to_DISO26img Hyperkalemia C0020461
DISO_to_DISO26img Paralysis C0522224
DISO_to_DISO25img Paralysed C0522224
DISO_to_DISO24img Kidney Diseases C0022658
DISO_to_DISO22img ALDOSTERONISM C0020428
DISO_to_DISO22img Gitelman Syndrome C0268450
DISO_to_DISO22img Rhabdomyolysis C0035410
DISO_to_DISO21img Arrhythmias, Cardiac C0003811
DISO_to_CHEM18img 720-724 DIURETICS C0012798
DISO_to_DISO18img DEFIC MAGNESIUM C0024473
DISO_to_CHEM17img Magnesium C0024467
DISO_to_DISO17img Hyperkalemia C0020461
DISO_to_DISO17img Hyponatremia C0020625
DISO_to_CHEM16img Symporters C0598849
DISO_to_DISO16img Bartter Disease C0004775
DISO_to_DISO16img RHABDOMYOLYSIS C0035410
DISO_to_DISO15img ALDOSTERONISM C0020428
DISO_to_DISO15img Hyponatremia C0020625
DISO_to_CHEM13img DRUG RECEPT C0034799
DISO_to_CHEM13img Receptors, Drug C0034799
DISO_to_DISO13img Acidosis, Renal Tubular C0001126
DISO_to_DISO13img Quadriplegia C0034372
DISO_to_PHEN13img genetic aspects C0017399
DISO_to_DISO12img ALKALOSIS C0002063
DISO_to_DISO12img Arrhythmias, Cardiac C0003811
DISO_to_CHEM11img Carrier Protein C0007292
DISO_to_DISO11img Quadriplegia C0034372
DISO_to_CHEM10img 720-724 DIURETICS C0012798
DISO_to_CHEM10img Calcium C0006675
DISO_to_DISO10img Acidosis, Renal Tubular C0001126
DISO_to_DISO10img Kidney Diseases C0022658
DISO_to_DISO10img Renal Tubular Transport, Inborn Errors C0035091
DISO_to_CHEM9img Antihypertensive Agents C0003364
DISO_to_DISO9img DEFIC MAGNESIUM C0024473
DISO_to_DISO9img Long QT Syndrome C0023976
DISO_to_DISO9img Sjogren's Syndrome C1527336
DISO_to_DISO9img Thyrotoxicosis C0040156
DISO_to_CHEMmay_treatimg 2,4,7-Pteridinetriamine, 6-phenyl- C0040869
DISO_to_CHEMmay_treatimg AMILORIDE C0002502
DISO_to_CHEMmay_treatimg AMILORIDE HCL 5MG ORAL TABLET C0687831
DISO_to_CHEMmay_treatimg AMILORIDE HYDROCHLORIDE C0546849
DISO_to_CHEMmay_preventimg Acetate, Potassium C0137984
DISO_to_CHEMmay_preventimg CHLORIDE (AS POTASSIUM) C0032825
DISO_to_CHEMmay_treatimg Dibasic potassium phosphate C0138037
DISO_to_CHEMmay_preventimg Dibasic potassium phosphate 1.66 MEQ/ML / Monobasic potassium phosphate 1.65 MEQ/ML Injectable Solution C0994978
DISO_to_CHEMmay_treatimg K+ Acetate 0.2 MEQ/ML Injectable Solution C0979617
DISO_to_CHEMmay_preventimg K+ Acetate 2 MEQ/ML Injectable Solution C0772994
DISO_to_CHEMmay_preventimg K+ Acetate 4 MEQ/ML Injectable Solution C0772995
DISO_to_CHEMmay_treatimg K+ Chloride 0.125 MEQ/ML Oral Solution C0979641
DISO_to_CHEMmay_preventimg K+ Chloride 0.4 MEQ/ML Injectable Solution C0979659
DISO_to_CHEMmay_treatimg K+ Chloride 0.67 MEQ/ML Injectable Solution C0979632
DISO_to_CHEMmay_treatimg K+ Chloride 1 MEQ/ML Oral Solution C0979640
DISO_to_CHEMmay_preventimg K+ Chloride 1.5 MEQ/ML Injectable Solution C0703805
DISO_to_CHEMmay_treatimg K+ Chloride 10 MEQ Extended Release Tablet [K-Dur] C0710555
DISO_to_CHEMmay_treatimg K+ Chloride 13 MEQ Enteric Coated Tablet C0979639
DISO_to_CHEMmay_treatimg K+ Chloride 2 MEQ/ML Injectable Solution C0703807
DISO_to_CHEMmay_preventimg K+ Chloride 2 MEQ/ML Oral Solution C0979657
DISO_to_CHEMmay_preventimg K+ Chloride 2.4 MEQ Enteric Coated Tablet C0979642
DISO_to_CHEMmay_preventimg K+ Chloride 2.4 MEQ/ML Injectable Solution C0784029
DISO_to_CHEMmay_treatimg K+ Chloride 2.67 MEQ/ML Oral Solution C0981676
DISO_to_CHEMmay_treatimg K+ Chloride 20 MEQ Extended Release Tablet [K-Dur] C0979644
DISO_to_CHEMmay_treatimg K+ Chloride 25 MEQ Oral Tablet C0979652
DISO_to_CHEMmay_treatimg K+ Chloride 3 MEQ/ML Injectable Solution C0784030
DISO_to_CHEMmay_treatimg K+ Chloride 3.2 MEQ/ML Injectable Solution C0982846
DISO_to_CHEMmay_treatimg K+ Chloride 4 MEQ Enteric Coated Tablet C0979661
DISO_to_CHEMmay_treatimg K+ Chloride 4 MEQ/ML Oral Solution C0982496
DISO_to_CHEMmay_treatimg K+ Chloride 6.7 MEQ Enteric Coated Tablet C0979662
DISO_to_CHEMmay_preventimg K+ Chloride 6.7 MEQ Extended Release Tablet C0979663
DISO_to_CHEMmay_treatimg K+ Chloride 8 MEQ Enteric Coated Tablet C0979664
DISO_to_CHEMmay_treatimg K+ bicarbonate 20 MEQ Oral Tablet C0979622
DISO_to_CHEMmay_preventimg K+ bicarbonate 6.5 MEQ Oral Tablet C0979628
DISO_to_CHEMmay_preventimg K+ citrate 260 MG Oral Tablet C0979666
DISO_to_CHEMmay_treatimg K+ gluconate 2 MEQ Oral Tablet C0773014
DISO_to_CHEMmay_preventimg K+ gluconate 2.2 MEQ Oral Tablet C0982848
DISO_to_CHEMmay_preventimg K+ gluconate 2.35 MEQ Oral Tablet C0691739
DISO_to_CHEMmay_preventimg K+ gluconate 2.5 MEQ Oral Tablet C0777470
DISO_to_CHEMmay_preventimg K+ gluconate 2.6 MEQ Oral Tablet C0982849
DISO_to_CHEMmay_preventimg K+ gluconate 5 MEQ Oral Tablet C0979672
DISO_to_CHEMmay_preventimg K+ gluconate 6.66 MEQ Oral Tablet C0994983
DISO_to_CHEMmay_treatimg K+ phosphate 1450 MG Oral Capsule C0979687
DISO_to_CHEMmay_treatimg K+,CHELATED 99 MG Oral Tablet C0979691
DISO_to_CHEMmay_preventimg KHCO3 C0071751
DISO_to_CHEMmay_preventimg Monobasic K+ phosphate 0.0408 MEQ/ML Oral Solution C0775824
DISO_to_CHEMmay_preventimg Monobasic potassium phosphate C0138038
DISO_to_CHEMmay_treatimg POTASSIUM (AS PHOSPHATE) C0071778
DISO_to_CHEMmay_preventimg POTASSIUM BICARBONATE @ @ POWDER (GM) C0979629
DISO_to_CHEMmay_preventimg POTASSIUM BITARTRATE @ @ POWDER (GM) C0979630
DISO_to_CHEMmay_treatimg POTASSIUM TRIPOLYPHOSPHATE C0982356
DISO_to_CHEMmay_preventimg POTASSIUM,CHELATED C0872910
DISO_to_CHEMassociated_withimg Potassium C0032821
DISO_to_CHEMmay_treatimg Potassium Acetate C0137984
DISO_to_CHEMmay_treatimg Potassium Chloride C0032825
DISO_to_CHEMmay_treatimg Potassium Chloride 0.1 MEQ/ML Injectable Solution C0979637
DISO_to_CHEMmay_preventimg Potassium Chloride 0.167 MEQ/ML Oral Solution C0981677
DISO_to_CHEMmay_preventimg Potassium Chloride 0.2 MEQ/ML Injectable Solution C0979645
DISO_to_CHEMmay_preventimg Potassium Chloride 0.3 MEQ/ML Injectable Solution C0979656
DISO_to_CHEMmay_treatimg Potassium Chloride 1.33 MEQ/ML Oral Solution C0979646
DISO_to_CHEMmay_preventimg Potassium Chloride 10 MEQ Extended Release Capsule C1162087
DISO_to_CHEMmay_preventimg Potassium Chloride 10 MEQ Extended Release Tablet C1693611
DISO_to_CHEMmay_preventimg Potassium Chloride 10 MEQ Oral Tablet C1298318
DISO_to_CHEMmay_treatimg Potassium Chloride 20 MEQ Extended Release Tablet C0690058
DISO_to_CHEMmay_treatimg Potassium Chloride 8 MEQ Extended Release Capsule C0982847
DISO_to_CHEMmay_preventimg Potassium Chloride 8 MEQ Extended Release Tablet C0979665
DISO_to_CHEMmay_preventimg Potassium Chloride 8 MEQ Oral Tablet C0981654
DISO_to_CHEMmay_preventimg Potassium Citrate C0137996
DISO_to_CHEMmay_preventimg Potassium bitartrate C0727538
DISO_to_CHEMmay_treatimg Potassium gluconate C0301527
DISO_to_CHEMmay_treatimg Potassium gluconate 1.33 MEQ/ML Oral Solution C0979671
DISO_to_CHEMmay_treatimg SPIRONOLACTONE 100 MG ORAL TABLET C0690395
DISO_to_CHEMmay_treatimg SPIRONOLACTONE 25 MG ORAL TABLET C0980346
DISO_to_CHEMmay_treatimg SPIRONOLACTONE 50 MG ORAL TABLET C0690397
DISO_to_CHEMmay_treatimg SPIRONOLACTONE @ @ POWDER (GM) C0980347
DISO_to_CHEMmay_treatimg Spironolactone C0037982
DISO_to_CHEMmay_treatimg TRIAMTERENE 100 MG ORAL CAPSULE C0690636
DISO_to_CHEMmay_treatimg TRIAMTERENE 50 MG ORAL CAPSULE C0690637
DISO_to_CHEMmay_treatimg Triamterene C0040869
DISO_to_CHEMmay_preventimg potassium bicarbonate 0.208 MEQ/ML Oral Solution C0979624
DISO_to_CHEMmay_treatimg potassium citrate 10 MEQ Extended Release Tablet C0692842
DISO_to_CHEMmay_preventimg potassium citrate 5 MEQ Extended Release Tablet C0692836
DISO_to_DISOclassifiesimg (Disorders of fluid, electrolyte and acid-base balance) or (electrolyte disorders) C0267994
DISO_to_DISOmapped_toimg Acute hypokalaemia C0268015
DISO_to_DISOmapped_toimg Chronic hypokalaemia C0268016
DISO_to_DISOisaimg Gitelman Syndrome C0268450
DISO_to_DISOmapped_toimg Hyperkaluria C0268018
DISO_to_DISOisaimg Hypokalaemia with normal acid-base balance C0342590
DISO_to_DISOmapped_toimg Hypokalaemia, ECF to ICF shifts C0268020
DISO_to_DISOmapped_toimg Hypokalaemia, gastrointestinal losses C0268019
DISO_to_DISOmapped_toimg Hypokalaemia, inadequate intake C0268017
DISO_to_DISOmapped_toimg Hypokalemia C0020621
DISO_to_DISOisaimg Hypokalemic alkalosis C0085570
DISO_to_DISOdisease_has_findingimg Juxtaglomerular Cell Tumor C0334331
DISO_to_DISOdisease_has_findingimg Malignant Pancreatic Vipoma C1881586
DISO_to_DISOmapped_toimg POTASSIUM SERUM DECREASED C0595885
DISO_to_DISOdisease_has_findingimg Pancreatic Vipoma C2033037
DISO_to_DISOmapped_toimg Paraneoplastic hypokalaemia C1321136
DISO_to_DISOmapped_toimg Potassium Deficiency C0032827
DISO_to_DISOmapped_toimg Potassium depletion C1971021
DISO_to_PHENmapped_toimg Drug-induced hypokalaemia C0342591
DISO_to_PHENisaimg Hypokalaemic acidosis C0342589
Genes (20)

Species:
human : 20
SpeciesGeneGeneIdGene NameEvidence
HumanSLC26A7115111solute carrier family 26 (anion exchanger), member 7
img GENERIF, Score=1000, Pubmed Id: 16524946, UMLKSK CUI: C0020621
HumanKCNE310008potassium voltage-gated channel, Isk-related family, member 3
img OMIM, Score=1000, UMLKSK CUI: C0020621
img OMIM, Score=1000, UMLKSK CUI: C0020621
HumanAIP9049aryl hydrocarbon receptor interacting protein
img OMIM, Score=1000, UMLKSK CUI: C0020621
HumanBSND7809Bartter syndrome, infantile, with sensorineural deafness (Barttin)
img OMIM, Score=1000, UMLKSK CUI: C0020621
HumanSLC12A36559solute carrier family 12 (sodium/chloride transporter), member 3
img OMIM, Score=1000, UMLKSK CUI: C0020621
HumanSLC12A16557solute carrier family 12 (sodium/potassium/chloride transporter), member 1
img OMIM, Score=1000, UMLKSK CUI: C0020621
HumanSLC2A26514solute carrier family 2 (facilitated glucose transporter), member 2
img OMIM, Score=1000, UMLKSK CUI: C0020621
HumanSCNN1G6340sodium channel, non-voltage-gated 1, gamma subunit
img OMIM, Score=1000, UMLKSK CUI: C0020621
HumanSCNN1B6338sodium channel, non-voltage-gated 1, beta subunit
img OMIM, Score=1000, UMLKSK CUI: C0020621
HumanSCN4A6329sodium channel, voltage-gated, type IV, alpha subunit
img OMIM, Score=1000, UMLKSK CUI: C0020621
img OMIM, Score=1000, UMLKSK CUI: C0020621
HumanPTEN5728phosphatase and tensin homolog
img OMIM, Score=1000, UMLKSK CUI: C0020621
HumanSMAD44089SMAD family member 4
img OMIM, Score=1000, UMLKSK CUI: C0020621
HumanKCNJ23759potassium inwardly-rectifying channel, subfamily J, member 2
img OMIM, Score=1000, UMLKSK CUI: C0020621
img OMIM, Score=761, UMLKSK CUI: C0020621
HumanKCNJ13758potassium inwardly-rectifying channel, subfamily J, member 1
img OMIM, Score=1000, UMLKSK CUI: C0020621
HumanCYP11B11584cytochrome P450, family 11, subfamily B, polypeptide 1
img OMIM, Score=1000, UMLKSK CUI: C0020621
HumanCLCNKB1188chloride channel, voltage-sensitive Kb
img OMIM, Score=1000, UMLKSK CUI: C0020621
HumanCLCNKA1187chloride channel, voltage-sensitive Ka
img OMIM, Score=1000, UMLKSK CUI: C0020621
HumanCACNA1S779calcium channel, voltage-dependent, L type, alpha 1S subunit
img OMIM, Score=1000, UMLKSK CUI: C0020621
img OMIM, Score=1000, UMLKSK CUI: C0020621
img OMIM, Score=1000, UMLKSK CUI: C0020621
HumanBMPR1A657bone morphogenetic protein receptor, type IA
img OMIM, Score=1000, UMLKSK CUI: C0020621
HumanADRB2154adrenoceptor beta 2, surface
img GENERIF, Score=1000, Pubmed Id: 17292646, UMLKSK CUI: C0020621
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0020621Hypokalemia0self