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Details
Link-It Detail - Disease - Hypertension, Pulmonary
Debug Stats
  • ### Total Build Time: 101 ms 49.773 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 396 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 267 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 549 bytes
  • CONCEPT_CHILDREN gt=3 ms Completed: 3 ms rowSize= 575 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.500 KB
  • CONCEPT_RELATIONSHIPS gt=78 ms Completed: 78 ms rowSize= 14.475 KB
  • CONCEPT_GENES gt=14 ms Completed: 14 ms rowSize= 30.686 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.157 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
Hypertension, Pulmonary C0020542
Pulmonary Hypertension
Definition (1)
Increased VASCULAR RESISTANCE in the PULMONARY CIRCULATION, usually secondary to HEART DISEASES or LUNG DISEASES.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (1)
img Lung Diseases C0024115
Children (1)
img Persistent Fetal Circulation Syndrome C0031190
Ancestral Roots
RootRoot Plus OneDepthParent
img Respiratory Tract Diseases C0035242img Lung Diseases C00241153img Lung Diseases C0024115
Relationships (253)

Relation Types:
diso_​to_​anat : 16
diso_​to_​chem : 129
diso_​to_​diso : 80
diso_​to_​gene : 2
diso_​to_​phen : 2
diso_​to_​phys : 24


Relationships:
none : 157
clinically_​similar : 1
gene_​associated_​with_​disease : 2
isa : 10
mapped_​to : 5
may_​treat : 77
related_​to : 1
Page Size
Current 25
  Page 1 of 11
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO737img Complication Aspects C1171258
DISO_to_ANAT522img Pulmonary Artery C0034052
DISO_to_CHEM425img Antihypertensive Agents C0003364
DISO_to_DISO407img Complication Aspects C1171258
DISO_to_ANAT321img Pulmonary Artery C0034052
DISO_to_CHEM302img Antihypertensive Agents C0003364
DISO_to_CHEM280img 815-816 VASODILATING AGENTS C0042402
DISO_to_CHEM277img 815-816 VASODILATING AGENTS C0042402
DISO_to_PHEN270img genetic aspects C0017399
DISO_to_DISO254img chemically induced C0007994
DISO_to_DISO241img Pulmonary Embolism C0034065
DISO_to_ANAT234img In Blood C0005768
DISO_to_CHEM220img Piperazines C0031958
DISO_to_CHEM207img Piperazines C0031958
DISO_to_CHEM203img Sulfones C0038761
DISO_to_DISO195img Heart Failure C0018801
DISO_to_DISO194img Anoxia C0003130
DISO_to_CHEM191img Epoprostenol C0033567
DISO_to_DISO185img Scleroderma, Systemic C0036421
DISO_to_DISO183img Anoxia C0003130
DISO_to_PHEN179img genetic aspects C0017399
DISO_to_CHEM174img Sulfonamides C0038760
DISO_to_ANAT170img Lung C0024109
DISO_to_DISO166img Pulmonary Embolism C0034065
DISO_to_DISO164img DYSFUNCTION, RIGHT VENTRICULAR C0242707
Genes (34)

Species:
human : 34
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanUTS2D257313
img GENERIF, Score=1000, Pubmed Id: 18000598, UMLKSK CUI: C0020542
HumanNOX450507NADPH oxidase 4
img GENERIF, Score=1000, Pubmed Id: 17585072, UMLKSK CUI: C0020542
HumanGREM126585gremlin 1, DAN family BMP antagonist
img GENERIF, Score=1000, Pubmed Id: 18469115, UMLKSK CUI: C0020542
HumanUTS210911urotensin 2
img GENERIF, Score=1000, Pubmed Id: 15618545, UMLKSK CUI: C0020542
HumanLYVE110894lymphatic vessel endothelial hyaluronan receptor 1
INFERRED, Score=800, UMLKSK CUI: C0020542
HumanARHGEF69459Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
img GENERIF, Score=1000, Pubmed Id: 15242552, UMLKSK CUI: C0020542
HumanPLA2G77941phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
img GENERIF, Score=861, Pubmed Id: 17509958, UMLKSK CUI: C0020542
HumanVWF7450von Willebrand factor
img GENERIF, Score=673, Pubmed Id: 14507115, UMLKSK CUI: C0020542
HumanAVSD17446atrioventricular septal defect 1
img OMIM, Score=1000, UMLKSK CUI: C0020542
HumanTRPC67225transient receptor potential cation channel, subfamily C, member 6
img GENERIF, Score=734, Pubmed Id: 15358862, UMLKSK CUI: C0020542
HumanTNF7124tumor necrosis factor
INFERRED, Score=800, UMLKSK CUI: C0020542
HumanTGFA7039transforming growth factor, alpha
img GENERIF, Score=1000, Pubmed Id: 12896876, UMLKSK CUI: C0020542
HumanSLC6A46532solute carrier family 6 (neurotransmitter transporter), member 4
img GENERIF, Score=1000, Pubmed Id: 14530202, UMLKSK CUI: C0020542
HumanPTGS25743prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
img GENERIF, Score=1000, Pubmed Id: 12391278, UMLKSK CUI: C0020542
HumanPPARG5468peroxisome proliferator-activated receptor gamma
img GENERIF, Score=861, Pubmed Id: 12714563, UMLKSK CUI: C0020542
img GENERIF, Score=1000, Pubmed Id: 18382765, UMLKSK CUI: C0020542
img GENERIF, Score=1000, Pubmed Id: 18317434, UMLKSK CUI: C0020542
HumanNPPB4879natriuretic peptide B
img GENERIF, Score=1000, Pubmed Id: 18160811, UMLKSK CUI: C0020542
img GENERIF, Score=1000, Pubmed Id: 16236896, UMLKSK CUI: C0020542
HumanNOS34846nitric oxide synthase 3 (endothelial cell)
img GAD, Score=1000, Pubmed Id: 14682408, UMLKSK CUI: C0020542
HumanNOS24843nitric oxide synthase 2, inducible
img GENERIF, Score=1000, Pubmed Id: 16456243, UMLKSK CUI: C0020542
HumanJUN3725jun proto-oncogene
img GENERIF, Score=861, Pubmed Id: 12909593, UMLKSK CUI: C0020542
HumanTNC3371tenascin C
img GENERIF, Score=660, Pubmed Id: 16782755, UMLKSK CUI: C0020542
HumanGJA12697gap junction protein, alpha 1, 43kDa
img OMIM, Score=1000, UMLKSK CUI: C0020542
HumanGBA2629glucosidase, beta, acid
img OMIM, Score=1000, UMLKSK CUI: C0020542
HumanSLC37A42542solute carrier family 37 (glucose-6-phosphate transporter), member 4
img OMIM, Score=1000, UMLKSK CUI: C0020542
HumanFLNA2316filamin A, alpha
img OMIM, Score=1000, UMLKSK CUI: C0020542
HumanEDN11906endothelin 1
img GENERIF, Score=1000, Pubmed Id: 17291632, UMLKSK CUI: C0020542
img GENERIF, Score=861, Pubmed Id: 15979050, UMLKSK CUI: C0020542
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0020542Hypertension, Pulmonary0self