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Details
Link-It Detail - Disease - Hypertension, Malignant
Debug Stats
  • ### Total Build Time: 205 ms 20.609 KB
  • CONCEPT_NAME gt=11 ms Completed: 11 ms rowSize= 396 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 406 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=12 ms Completed: 12 ms rowSize= 548 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.500 KB
  • CONCEPT_RELATIONSHIPS gt=162 ms Completed: 162 ms rowSize= 13.655 KB
  • CONCEPT_GENES gt=13 ms Completed: 13 ms rowSize= 2.760 KB
  • CONCEPT_XREFS gt=4 ms Completed: 4 ms rowSize= 1.157 KB
  • CONCEPT_ANCILLARY gt=2 ms Completed: 2 ms rowSize= 14 bytes
  • Reload Stats
Disease (2)
Hypertension, Malignant C0020540
Malignant Hypertension
Definition (1)
A condition of markedly elevated BLOOD PRESSURE with DIASTOLIC PRESSURE usually greater than 120 mm Hg. Malignant hypertension is characterized by widespread vascular damage, PAPILLEDEMA, retinopathy, HYPERTENSIVE ENCEPHALOPATHY, and renal dysfunction.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (1)
img Hypertension C0020538
Ancestral Roots
RootRoot Plus OneDepthParent
img Cardiovascular Diseases C0007222img Vascular Diseases C00423734img Hypertension C0020538
Relationships (87)

Relation Types:
diso_​to_​anat : 2
diso_​to_​chem : 68
diso_​to_​diso : 15
diso_​to_​phen : 1
diso_​to_​phys : 1


Relationships:
none : 17
clinically_​similar : 3
isa : 3
location_​of : 1
may_​treat : 63
Page Size
Current 25
  Page 1 of 4
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO38img Complication Aspects C1171258
DISO_to_DISO29img Complication Aspects C1171258
DISO_to_CHEM14img Antihypertensive Agents C0003364
DISO_to_CHEM11img Antihypertensive Agents C0003364
DISO_to_CHEM11img Renin C0035094
DISO_to_DISO9img Adrenal Gland Neoplasms C0001624
DISO_to_DISO9img Retinal Diseases C0035309
DISO_to_DISO9img chemically induced C0007994
DISO_to_PHYS9img Blood Pressure C0005823
DISO_to_ANAT7img Kidney C0022646
DISO_to_CHEM7img Angiotensin II C0003009
DISO_to_CHEM6img Cytochrome P-450 CYP1A1 C0059735
DISO_to_DISO6img Acute kidney injury C2609414
DISO_to_DISO6img Hypertension due to renovascular disease C0020545
DISO_to_DISO6img Purpura, Thrombotic Thrombocytopenic C0034155
DISO_to_DISO6img Retinal Diseases C0035309
DISO_to_PHEN6img genetic aspects C0017399
DISO_to_ANATlocation_ofimg Cardiovascular System C0007226
DISO_to_CHEMmay_treatimg 1(2H)-Phthalazinone Hydrazone C0020223
DISO_to_CHEMmay_treatimg 1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)- C0060180
DISO_to_CHEMmay_treatimg 2,3-Dihydro-3-hydroxy-2-imino-6-(1-piperidinyl)-4-pyrimidinamine C0026196
DISO_to_CHEMmay_treatimg 2-[N-p'-Tolyl-N-(m'-hydroxyphenyl)aminomethyl]imidazoline Monomethanesulfonate C0733398
DISO_to_CHEMmay_treatimg 2H-1,2,4-Benzothiadiazine, 7-chloro-3-methyl-, 1,1-dioxide C0012022
DISO_to_CHEMmay_treatimg 6-Chloro-2,3,4,5-tetrahydro-1-(p-hydroxyphenyl)-1H-3-benzazepine-7,8-diol methanesulfonate(salt) C0700481
DISO_to_CHEMmay_treatimg 8 ML Labetalol hydrochloride 5 MG/ML Prefilled Syringe C0995031
Genes (2)

Species:
human : 2
SpeciesGeneGeneIdGene NameEvidence
HumanADAMTS1311093ADAM metallopeptidase with thrombospondin type 1 motif, 13
img GENERIF, Score=1000, Pubmed Id: 18332284, UMLKSK CUI: C0020540
HumanAGT183angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
img GENERIF, Score=1000, Pubmed Id: 17921816, UMLKSK CUI: C0020540
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0020540Hypertension, Malignant0self