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Details
Link-It Detail - Disease - Hypertension
Debug Stats
  • ### Total Build Time: 406 ms 46.400 KB
  • CONCEPT_NAME gt=4 ms Completed: 4 ms rowSize= 322 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 1.558 KB
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 240 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 553 bytes
  • CONCEPT_CHILDREN gt=1 ms Completed: 1 ms rowSize= 1.414 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.505 KB
  • CONCEPT_RELATIONSHIPS gt=341 ms Completed: 341 ms rowSize= 16.433 KB
  • CONCEPT_GENES gt=57 ms Completed: 57 ms rowSize= 23.229 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.146 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Hypertension C0020538
Definition (1)

Blood pressure is the force of your blood pushing against the walls of your arteries. Each time your heart beats, it pumps out blood into the arteries. Your blood pressure is highest when your heart beats, pumping the blood. This is called systolic pressure. When your heart is at rest, between beats, your blood pressure falls. This is the diastolic pressure.

Your blood pressure reading uses these two numbers, the systolic and diastolic pressures. Usually they are written one above or before the other. A reading of

  • 120/80 or lower is normal blood pressure
  • 140/90 or higher is high blood pressure
  • Between 120 and 139 for the top number, or between 80 and 89 for the bottom number is prehypertension

High blood pressure usually has no symptoms, but it can cause serious problems such as stroke, heart failure, heart attack and kidney failure. You can control high blood pressure through healthy lifestyle habits and taking medicines, if needed.

NIH: National Heart, Lung, and Blood Institute

Semantic Types (2)
Disease or Syndrome (T047)
Sign or Symptom (T184)
Parents (1)
img Vascular Diseases C0042373
Children (3)
img Hypertension, Malignant C0020540
img Hypertension, Pregnancy-Induced C0340274
img Hypertension, Renal C0020544
Ancestral Roots
RootRoot Plus OneDepthParent
img Cardiovascular Diseases C0007222img Vascular Diseases C00423733img Vascular Diseases C0042373
Relationships (1023)

Relation Types:
diso_​to_​anat : 45
diso_​to_​chem : 656
diso_​to_​diso : 257
diso_​to_​gene : 20
diso_​to_​phen : 6
diso_​to_​phys : 39


Relationships:
none : 357
associated_​with : 56
classifies : 2
disease_​has_​finding : 2
disease_​may_​have_​finding : 35
gene_​associated_​with_​disease : 18
gene_​product_​malfunction_​associated_​with_​disease : 3
isa : 28
location_​of : 1
mapped_​to : 7
may_​treat : 505
parent_​is_​cdrh : 1
permuted_​term_​of : 1
related_​to : 3
use : 4
Page Size
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Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO4473img Complication Aspects C1171258
DISO_to_CHEM4007img Antihypertensive Agents C0003364
DISO_to_DISO3690img Complication Aspects C1171258
DISO_to_PHYS3426img Blood Pressure C0005823
DISO_to_CHEM3351img Antihypertensive Agents C0003364
DISO_to_PHYS2030img Blood Pressure C0005823
DISO_to_PHEN1749img genetic aspects C0017399
DISO_to_PHEN1594img genetic aspects C0017399
DISO_to_ANAT1524img In Blood C0005768
DISO_to_ANAT1220img In Blood C0005768
DISO_to_DISO955img Cardiovascular Diseases C0007222
DISO_to_DISO867img chemically induced C0007994
DISO_to_CHEM822img Angiotensin-Converting Enzyme Inhibitors C0003015
DISO_to_DISO808img Diabetes Mellitus, Non-Insulin-Dependent C0011860
DISO_to_DISO773img Obesity C0028754
DISO_to_CHEM728img Angiotensin II Type 1 Receptor Blockers C1449680
DISO_to_DISO708img Cardiovascular Diseases C0007222
DISO_to_DISO698img chemically induced C0007994
DISO_to_DISO657img Hypertrophy, Left Ventricular C0149721
DISO_to_DISO633img Hypertrophy, Left Ventricular C0149721
DISO_to_DISO631img Diabetes Mellitus, Non-Insulin-Dependent C0011860
DISO_to_CHEM620img Tetrazoles C0039703
DISO_to_CHEM584img Angiotensin-Converting Enzyme Inhibitors C0003015
DISO_to_DISO580img Obesity C0028754
DISO_to_ANAT542img Kidney C0022646
Genes (416)

Species:
human : 416
Page Size
Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanCD24100133941CD24 molecule
INFERRED, Score=800, UMLKSK CUI: C0020538
HumanCCR2729230chemokine (C-C motif) receptor 2
Click here to display 4 evidence detail records.
HumanNCF1C654817neutrophil cytosolic factor 1C pseudogene
img GENERIF, Score=1000, Pubmed Id: 15775784, UMLKSK CUI: C0020538
HumanLOC391533391533
INFERRED, Score=800, UMLKSK CUI: C0020538
HumanSLC6A18348932solute carrier family 6 (neutral amino acid transporter), member 18
img GENERIF, Score=1000, Pubmed Id: 18554081, UMLKSK CUI: C0020538
HumanSLC6A19340024solute carrier family 6 (neutral amino acid transporter), member 19
img GENERIF, Score=1000, Pubmed Id: 18671945, UMLKSK CUI: C0020538
HumanSTOX1219736storkhead box 1
INFERRED, Score=800, UMLKSK CUI: C0020538
HumanBBS12166379Bardet-Biedl syndrome 12
img OMIM, Score=1000, UMLKSK CUI: C0020538
HumanTRPM6140803transient receptor potential cation channel, subfamily M, member 6
img GENERIF, Score=1000, Pubmed Id: 18192217, UMLKSK CUI: C0020538
HumanBBS5129880Bardet-Biedl syndrome 5
img OMIM, Score=1000, UMLKSK CUI: C0020538
HumanTTC8123016tetratricopeptide repeat domain 8
img OMIM, Score=1000, UMLKSK CUI: C0020538
HumanKIR3DL3115653killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
INFERRED, Score=800, UMLKSK CUI: C0020538
HumanTMEM6791147transmembrane protein 67
img OMIM, Score=1000, UMLKSK CUI: C0020538
HumanARL684100ADP-ribosylation factor-like 6
img OMIM, Score=1000, UMLKSK CUI: C0020538
HumanCEP29080184centrosomal protein 290kDa
img OMIM, Score=1000, UMLKSK CUI: C0020538
HumanBBS1079738Bardet-Biedl syndrome 10
img OMIM, Score=1000, UMLKSK CUI: C0020538
HumanWNK465266WNK lysine deficient protein kinase 4
Click here to display 7 evidence detail records.
HumanWNK165125WNK lysine deficient protein kinase 1
Click here to display 5 evidence detail records.
HumanXYLT264132xylosyltransferase II
INFERRED, Score=800, UMLKSK CUI: C0020538
HumanXYLT164131xylosyltransferase I
INFERRED, Score=800, UMLKSK CUI: C0020538
HumanNOD264127nucleotide-binding oligomerization domain containing 2
INFERRED, Score=800, UMLKSK CUI: C0020538
HumanPAPPA260676pappalysin 2
INFERRED, Score=800, UMLKSK CUI: C0020538
HumanACE259272angiotensin I converting enzyme 2
Click here to display 6 evidence detail records.
HumanRETN56729resistin
img GENERIF, Score=1000, Pubmed Id: 17785630, UMLKSK CUI: C0020538
img GAD, Score=1000, Pubmed Id: 12629116, UMLKSK CUI: C0020538
HumanSUCNR156670succinate receptor 1
img GENERIF, Score=827, Pubmed Id: 15141213, UMLKSK CUI: C0020538
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0020538Hypertension0self