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Details
Link-It Detail - Disease - Hyperkalemia
Debug Stats
  • ### Total Build Time: 319 ms 25.954 KB
  • CONCEPT_NAME gt=6 ms Completed: 6 ms rowSize= 322 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 476 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 232 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=7 ms Completed: 7 ms rowSize= 563 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.526 KB
  • CONCEPT_RELATIONSHIPS gt=280 ms Completed: 280 ms rowSize= 13.667 KB
  • CONCEPT_GENES gt=23 ms Completed: 23 ms rowSize= 8.023 KB
  • CONCEPT_XREFS gt=3 ms Completed: 3 ms rowSize= 1.146 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Hyperkalemia C0020461
Definition (1)
Abnormally high potassium concentration in the blood, most often due to defective renal excretion. It is characterized clinically by electrocardiographic abnormalities (elevated T waves and depressed P waves, and eventually by atrial asystole). In severe cases, weakness and flaccid paralysis may occur. (Dorland, 27th ed)
Semantic Types (2)
Finding (T033)
Pathologic Function (T046)
Parents (1)
img Water-Electrolyte Imbalance C0043065
Ancestral Roots
RootRoot Plus OneDepthParent
img Nutritional and Metabolic Diseases C0028715img Metabolic Diseases C00255174img Water-Electrolyte Imbalance C0043065
Relationships (126)

Relation Types:
diso_​to_​anat : 4
diso_​to_​chem : 77
diso_​to_​diso : 41
diso_​to_​phen : 4


Relationships:
none : 49
associated_​with : 1
classifies : 1
isa : 6
mapped_​to : 10
may_​treat : 59
Page Size
Current 25
  Page 1 of 6
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO127img chemically induced C0007994
DISO_to_DISO117img chemically induced C0007994
DISO_to_ANAT99img In Blood C0005768
DISO_to_CHEM85img Potassium C0032821
DISO_to_DISO85img Complication Aspects C1171258
DISO_to_DISO77img Complication Aspects C1171258
DISO_to_CHEM41img Spironolactone C0037982
DISO_to_ANAT39img In Blood C0005768
DISO_to_CHEM37img Potassium C0032821
DISO_to_DISO32img Kidney Failure, Chronic C0022661
DISO_to_DISO27img Heart Failure C0018801
DISO_to_DISO26img Heart Failure C0018801
DISO_to_DISO26img Hypokalemia C0020621
DISO_to_CHEM24img Angiotensin-Converting Enzyme Inhibitors C0003015
DISO_to_CHEM24img Mineralocorticoid Receptor Antagonists C1579268
DISO_to_DISO24img Kidney Failure, Chronic C0022661
DISO_to_CHEM23img Mineralocorticoid Receptor Antagonists C1579268
DISO_to_CHEM22img Spironolactone C0037982
DISO_to_CHEM19img 720-724 DIURETICS C0012798
DISO_to_DISO18img Kidney Diseases C0022658
DISO_to_DISO17img Cardiac Arrest C0018790
DISO_to_DISO17img Hypokalemia C0020621
DISO_to_CHEM15img Antihypertensive Agents C0003364
DISO_to_DISO15img Cardiac Arrest C0018790
DISO_to_DISO15img Hypertension C0020538
Genes (9)

Species:
human : 9
SpeciesGeneGeneIdGene NameEvidence
HumanWNK465266WNK lysine deficient protein kinase 4
img OMIM, Score=1000, UMLKSK CUI: C0020461
HumanWNK165125WNK lysine deficient protein kinase 1
img OMIM, Score=1000, UMLKSK CUI: C0020461
HumanINVS27130inversin
img OMIM, Score=1000, UMLKSK CUI: C0020461
HumanSCNN1G6340sodium channel, non-voltage-gated 1, gamma subunit
img OMIM, Score=1000, UMLKSK CUI: C0020461
HumanSCNN1B6338sodium channel, non-voltage-gated 1, beta subunit
img OMIM, Score=1000, UMLKSK CUI: C0020461
HumanSCNN1A6337sodium channel, non-voltage-gated 1 alpha subunit
img OMIM, Score=1000, UMLKSK CUI: C0020461
HumanSCN4A6329sodium channel, voltage-gated, type IV, alpha subunit
img OMIM, Score=1000, UMLKSK CUI: C0020461
HumanRYR16261ryanodine receptor 1 (skeletal)
img OMIM, Score=1000, UMLKSK CUI: C0020461
HumanCYP11B21585cytochrome P450, family 11, subfamily B, polypeptide 2
img OMIM, Score=1000, UMLKSK CUI: C0020461
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0020461Hyperkalemia0self