Human | LOC100507436 | 100507436 | | INFERRED, Score=800, UMLKSK CUI: C0020456 |
Human | NCF1 | 653361 | neutrophil cytosolic factor 1 | The kinetics of p47phox activation was investigated by comparing neutrophils from diabetic and healthy subjects, and the mechanism of hyperglycemia-induced changes was studied by using neutrophil-like HL-60 cells as a model |
Human | SUMO4 | 387082 | small ubiquitin-like modifier 4 | INFERRED, Score=800, UMLKSK CUI: C0020456 |
Human | ZFP57 | 346171 | ZFP57 zinc finger protein | |
Human | PTPRVP | 148713 | protein tyrosine phosphatase, receptor type, V, pseudogene | INFERRED, Score=800, UMLKSK CUI: C0020456 |
Human | SPHKAP | 80309 | SPHK1 interactor, AKAP domain containing | Hyperglycemia stimulates SK1 activity via protein kinase C and oxidative stress-dependent pathways, leading to decreased apoptosis in vvascular smooth muscle |
Human | FTO | 79068 | fat mass and obesity associated | INFERRED, Score=800, UMLKSK CUI: C0020456 |
Human | TNMD | 64102 | tenomodulin | INFERRED, Score=800, UMLKSK CUI: C0020456 |
Human | HYMAI | 57061 | hydatidiform mole associated and imprinted (non-protein coding) | |
Human | RETN | 56729 | resistin | INFERRED, Score=800, UMLKSK CUI: C0020456 |
Human | GHRL | 51738 | ghrelin/obestatin prepropeptide | INFERRED, Score=800, UMLKSK CUI: C0020456 |
Human | FOXP3 | 50943 | forkhead box P3 | |
Human | NEUROG3 | 50674 | neurogenin 3 | INFERRED, Score=800, UMLKSK CUI: C0020456 |
Human | PTPN22 | 26191 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | |
Human | PASK | 23178 | PAS domain containing serine/threonine kinase | Results suggest that elevated glucose concentrations rapidly increase Per-Arnt-Sim kinase activity in pancreatic islet beta cells, followed by up-regulation by glucose of preproinsulin and pancreatic duodenum homeobox 1 gene expression |
Human | POLG2 | 11232 | polymerase (DNA directed), gamma 2, accessory subunit | INFERRED, Score=800, UMLKSK CUI: C0020456 |
Human | CAPN10 | 11132 | calpain 10 | detect the association among calpain-10(CAPN-10) gene polymorphism, hypentension and hyperglycemia |
Human | PPARGC1A | 10891 | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | INFERRED, Score=800, UMLKSK CUI: C0020456 |
Human | TXNIP | 10628 | thioredoxin interacting protein | first report to implicate TXNIP in Type 2 diabetes; effect of TXNIP on triglycerides is influenced by plasma glucose concentration, suggesting biological relevance of TXNIP variations may be particularly relevant in recurrent episodes of hyperglycaemia |
Human | ZMPSTE24 | 10269 | zinc metallopeptidase STE24 | |
Human | NAMPT | 10135 | nicotinamide phosphoribosyltransferase | The results indicate that hyperglycemia causes an increase in plasma visfatin levels and, as in people with diabetes mellitus type 2 but not with impaired glucose tolerance, this increase gets more prominent as the glucose intolerance worsens |
Human | SH2B3 | 10019 | SH2B adaptor protein 3 | |
Human | ARHGEF11 | 9826 | Rho guanine nucleotide exchange factor (GEF) 11 | INFERRED, Score=800, UMLKSK CUI: C0020456 |
Human | PRDX6 | 9588 | peroxiredoxin 6 | AOP2 protects hyperglycemia-induced lens epithelial cell apoptosis; this molecule may have the potential to prevent hyperglycemia-mediated complications in diabetes |
Human | ADIPOQ | 9370 | adiponectin, C1Q and collagen domain containing | study concluded that hyperglycaemia &/or hyperinsulinaemi per se regulated concentration & expression of leptin, adiponectin & acylation-stimulating protein in healthy lean young men, suggesting contribution to dysregulation of these hormones in diabetes |