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Details
Link-It Detail - Disease - Giant Cell Tumors
Debug Stats
  • ### Total Build Time: 174 ms 61.170 KB
  • CONCEPT_NAME gt=7 ms Completed: 7 ms rowSize= 332 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 338 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=5 ms Completed: 5 ms rowSize= 564 bytes
  • CONCEPT_CHILDREN gt=6 ms Completed: 6 ms rowSize= 562 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=6 ms Completed: 6 ms rowSize= 2.814 KB
  • CONCEPT_RELATIONSHIPS gt=99 ms Completed: 99 ms rowSize= 13.325 KB
  • CONCEPT_GENES gt=44 ms Completed: 44 ms rowSize= 41.915 KB
  • CONCEPT_XREFS gt=5 ms Completed: 5 ms rowSize= 1.151 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Giant Cell Tumors C0017525
Definition (1)
Tumors of bone tissue or synovial or other soft tissue characterized by the presence of giant cells. The most common are giant cell tumor of tendon sheath and GIANT CELL TUMOR OF BONE.
Semantic Types (1)
Neoplastic Process (T191)
Parents (1)
img Neoplasms, Connective Tissue C0027656
Children (1)
img Giant Cell Tumor of Bone C0206638
Ancestral Roots
RootRoot Plus OneDepthParent
img Neoplasms C0027651img Neoplasms by Histologic Type C00276525img Neoplasms, Connective Tissue C0027656
img Skin and Connective Tissue Diseases C0175166img Connective Tissue Diseases C00097824img Neoplasms, Connective Tissue C0027656
Relationships (44)

Relation Types:
diso_​to_​anat : 17
diso_​to_​diso : 25
diso_​to_​phen : 2


Relationships:
none : 24
is_​abnormal_​cell_​of_​disease : 5
is_​normal_​cell_​origin_​of_​disease : 2
is_​normal_​tissue_​origin_​of_​disease : 2
is_​not_​abnormal_​cell_​of_​disease : 1
is_​not_​normal_​cell_​origin_​of_​disease : 1
isa : 8
permuted_​term_​of : 1
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO54img Soft Tissue Neoplasms C0037579
DISO_to_DISO46img Soft Tissue Neoplasms C0037579
DISO_to_ANAT43img Tendons C0039508
DISO_to_ANAT41img Tendon structure C0039508
DISO_to_DISO28img Bone Neoplasms C0005967
DISO_to_DISO21img Bone Neoplasms C0005967
DISO_to_DISO19img Complication Aspects C1171258
DISO_to_DISO16img Pancreatic Neoplasms C0030297
DISO_to_PHEN16img genetic aspects C0017399
DISO_to_ANAT14img Osteoclasts C0029431
DISO_to_DISO13img Complication Aspects C1171258
DISO_to_DISO13img Spinal Neoplasms C0037939
DISO_to_ANAT12img Fingers C0016129
DISO_to_DISO12img Pigmented villonodular synovitis C0039106
DISO_to_DISO10img Pancreatic Neoplasm C0030297
DISO_to_DISO10img Skin Neoplasms C0037286
DISO_to_DISO9img Neoplasm Recurrence, Local C0027643
DISO_to_DISO9img Spinal Neoplasms C0037939
DISO_to_ANAT8img Osteoclast C0029431
DISO_to_DISO8img LOCAL NEOPL RECURRENCE C0027643
DISO_to_DISO8img Muscle Neoplasms C0282606
DISO_to_ANAT7img Synovial Membrane C0039099
DISO_to_DISO7img Dermatofibrosarcoma C0206647
DISO_to_PHEN7img genetic aspects C0017399
DISO_to_ANATis_abnormal_cell_of_diseaseimg Abnormal numbers of nuclei C0017526
Genes (27)

Species:
human : 27
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanSP7121340Sp7 transcription factor
INFERRED, Score=800, UMLKSK CUI: C0017525
HumanC1QTNF3114899C1q and tumor necrosis factor related protein 3
img NCI, Score=801, Pubmed Id: 14654242, UMLKSK CUI: C0017525
HumanUSP69098ubiquitin specific peptidase 6 (Tre-2 oncogene)
img NCI, Score=801, Pubmed Id: 15509545, UMLKSK CUI: C0017525
HumanTNFRSF11A8792tumor necrosis factor receptor superfamily, member 11a, NFKB activator
INFERRED, Score=800, UMLKSK CUI: C0017525
HumanTP638626tumor protein p63
img GENERIF, Score=1000, Pubmed Id: 18311114, UMLKSK CUI: C0017525
HumanTNFSF118600tumor necrosis factor (ligand) superfamily, member 11
img NCI, Score=801, Pubmed Id: 10574572, UMLKSK CUI: C0017525
img NCI, Score=801, Pubmed Id: 12419159, UMLKSK CUI: C0017525
img NCI, Score=801, Pubmed Id: 12865629, UMLKSK CUI: C0017525
img NCI, Score=801, Pubmed Id: 11336917, UMLKSK CUI: C0017525
img NCI, Score=801, Pubmed Id: 12419159, UMLKSK CUI: C0017525
HumanFGF238074fibroblast growth factor 23
img NCI, Score=801, Pubmed Id: 12970268, UMLKSK CUI: C0017525
img NCI, Score=801, Pubmed Id: 12970268, UMLKSK CUI: C0017525
img NCI, Score=801, Pubmed Id: 12970268, UMLKSK CUI: C0017525
HumanADAM128038ADAM metallopeptidase domain 12
img NCI, Score=801, Pubmed Id: 12456779, UMLKSK CUI: C0017525
img NCI, Score=801, Pubmed Id: 12456779, UMLKSK CUI: C0017525
img NCI, Score=801, Pubmed Id: 12456779, UMLKSK CUI: C0017525
img NCI, Score=801, Pubmed Id: 12456779, UMLKSK CUI: C0017525
HumanTERT7015telomerase reverse transcriptase
img GENERIF, Score=1000, Pubmed Id: 18204433, UMLKSK CUI: C0017525
HumanSRC6714v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
img GENERIF, Score=1000, Pubmed Id: 16465417, UMLKSK CUI: C0017525
HumanPDGFB5155platelet-derived growth factor beta polypeptide
img NCI, Score=801, Pubmed Id: 3442409, UMLKSK CUI: C0017525
HumanTNFRSF11B4982tumor necrosis factor receptor superfamily, member 11b
img NCI, Score=801, Pubmed Id: 12419159, UMLKSK CUI: C0017525
img NCI, Score=801, Pubmed Id: 12419159, UMLKSK CUI: C0017525
img NCI, Score=801, Pubmed Id: 11336917, UMLKSK CUI: C0017525
img NCI, Score=801, Pubmed Id: 11336917, UMLKSK CUI: C0017525
HumanNME14830NME/NM23 nucleoside diphosphate kinase 1
img NCI, Score=801, Pubmed Id: 9888669, UMLKSK CUI: C0017525
img NCI, Score=801, Pubmed Id: 11825445, UMLKSK CUI: C0017525
img NCI, Score=801, Pubmed Id: 11825445, UMLKSK CUI: C0017525
img NCI, Score=801, Pubmed Id: 9888669, UMLKSK CUI: C0017525
img NCI, Score=801, Pubmed Id: 14734076, UMLKSK CUI: C0017525
img NCI, Score=801, Pubmed Id: 14734076, UMLKSK CUI: C0017525
img NCI, Score=801, Pubmed Id: 9888669, UMLKSK CUI: C0017525
HumanMET4233met proto-oncogene
img NCI, Score=801, Pubmed Id: 10867643, UMLKSK CUI: C0017525
HumanHLA-DRB13123
img NCI, Score=801, Pubmed Id: 10674041, UMLKSK CUI: C0017525
HumanGRID22895glutamate receptor, ionotropic, delta 2
img NCI, Score=801, Pubmed Id: 10963968, UMLKSK CUI: C0017525
HumanFLI12313Fli-1 proto-oncogene, ETS transcription factor
img NCI, Score=801, Pubmed Id: 11519035, UMLKSK CUI: C0017525
HumanCTSK1513cathepsin K
img NCI, Score=801, Pubmed Id: 9028530, UMLKSK CUI: C0017525
img NCI, Score=801, Pubmed Id: 9028530, UMLKSK CUI: C0017525
HumanCDH111009cadherin 11, type 2, OB-cadherin (osteoblast)
img NCI, Score=801, Pubmed Id: 15509545, UMLKSK CUI: C0017525
HumanCD68968CD68 molecule
img NCI, Score=801, Pubmed Id: 7907656, UMLKSK CUI: C0017525
HumanCD36948CD36 molecule (thrombospondin receptor)
img NCI, Score=801, Pubmed Id: 10772961, UMLKSK CUI: C0017525
HumanCALCR799calcitonin receptor
INFERRED, Score=800, UMLKSK CUI: C0017525
HumanBSG682basigin (Ok blood group)
img GENERIF, Score=1000, Pubmed Id: 12898514, UMLKSK CUI: C0017525
HumanBMP6654bone morphogenetic protein 6
img NCI, Score=801, Pubmed Id: 11450699, UMLKSK CUI: C0017525
HumanAMFR267autocrine motility factor receptor, E3 ubiquitin protein ligase
img NCI, Score=801, Pubmed Id: 16325507, UMLKSK CUI: C0017525
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0017525Giant Cell Tumors0self